GENOMIC HEALTH, INC.
301 Penobscot Drive
Redwood City, California 94063
301 Penobscot Drive
Redwood City, California 94063
April 24, 2007
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
Office of Emerging Growth Companies
100 F Street, NE
Washington, D.C. 20549-6010
Attn: John D. Reynolds, Assistant Director
Securities and Exchange Commission
Division of Corporation Finance
Office of Emerging Growth Companies
100 F Street, NE
Washington, D.C. 20549-6010
Attn: John D. Reynolds, Assistant Director
| Re: | Genomic Health, Inc. | |
| Registration Statement on Form S-3 (File No. 333-141946) |
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Genomic Health, Inc. hereby requests that the Registration Statement referred to above be declared effective at 4:00 p.m. (Washington D.C. time) on Thursday, April 26, 2007, or as soon thereafter as practicable.
Please call Gabriella A. Lombardi of Pillsbury Winthrop Shaw Pittman LLP at (650) 233-4670 to confirm the effectiveness of the Registration Statement.
Very truly yours,
GENOMIC HEALTH, INC.
| By: | /s/ G. Bradley Cole | | ||
| G. Bradley Cole | ||||
| Executive Vice President | ||||
| and Chief Financial Officer |
| cc: | Randal W. Scott, Ph.D. | |
| Stanton D. Wong | ||
| Gabriella A. Lombardi |