GENOMIC HEALTH, INC.
301 Penobscot Drive
Redwood City, California 94063
April 24, 2007
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
Office of Emerging Growth Companies
100 F Street, NE
Washington, D.C. 20549-6010
Attn: John D. Reynolds, Assistant Director
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Re: | | Genomic Health, Inc. |
| | Registration Statement on Form S-3 (File No. 333-141946) |
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Genomic Health, Inc. hereby requests that the Registration Statement referred to above be declared effective at 4:00 p.m. (Washington D.C. time) on Thursday, April 26, 2007, or as soon thereafter as practicable.
Please call Gabriella A. Lombardi of Pillsbury Winthrop Shaw Pittman LLP at (650) 233-4670 to confirm the effectiveness of the Registration Statement.
Very truly yours,
GENOMIC HEALTH, INC.
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By: | | /s/ G. Bradley Cole | |
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| | G. Bradley Cole | | |
| | Executive Vice President | | |
| | and Chief Financial Officer | | |
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cc: | | Randal W. Scott, Ph.D. |
| | Stanton D. Wong |
| | Gabriella A. Lombardi |