Certification Pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002; provided by the Chief Executive Officer and Chief Financial Officer, based on each such officer’s knowledge and belief.
The undersigned officers of Nuveen Multi-Strategy Income and Growth Fund (the “Fund”) certify that, to the best of each such officer’s knowledge and belief:
| 1. | The Form N-CSR of the Fund for the period ended December 31, 2008 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and | ||
| 2. | The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Fund. |
Date: March 9, 2009
| s/ Gifford R. Zimmerman | ||||
| Gifford R. Zimmerman | ||||
| Chief Administrative Officer (principal executive officer) | ||||
| s/ Stephen D. Foy | ||||
| Stephen D. Foy | ||||
| Vice President, Controller (principal financial officer) | ||||