EXHIBIT 99.1
JOINT FILING AGREEMENT
In accordance with Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that this Statement on Schedule 13G relating to the Common Stock of aTyr Pharma, Inc. is being filed with the Securities and Exchange Commission on behalf of each of them.
February 16, 2016
| BAKER BROS. ADVISORS LP |
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| By: Baker Bros. Advisors (GP) LLC, its general partner |
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| By: | /s/ Scott L. Lessing |
| | Name: Scott L. Lessing |
| | Title: President |
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| BAKER BROS. ADVISORS (GP) LLC |
| | |
| By: | /s/ Scott L. Lessing |
| | Name: Scott L. Lessing |
| | Title: President |
| | |
| /s/ Julian C. Baker |
| Julian C. Baker |
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| /s/ Felix J. Baker |
| Felix J. Baker |