AnaptysBio (ANAB) SC 13G Anaptysbio Inc

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934
(Amendment No.     )*

AnaptysBio, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

032724106

(CUSIP Number)

January 26, 2017

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

o Rule 13d-1(b)

x Rule 13d-1(c)

o Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP No. 032724106						13G
	1.	Names of Reporting Persons HBM Healthcare Investments (Cayman) Ltd.
	2.	Check the Appropriate Box if a Member of a Group (See Instructions)
		(a)		o
		(b)		o
	3.	SEC Use Only
	4.	Citizenship or Place of Organization Cayman Islands, British West Indies
Number of Shares Beneficially Owned by Each Reporting Person With:			5.		Sole Voting Power 942,835 (1)
			6.		Shared Voting Power 0
			7.		Sole Dispositive Power 942,835 (1)
			8.		Shared Dispositive Power 0
	9.	Aggregate Amount Beneficially Owned by Each Reporting Person942,835 (1)
	10.	Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions)  o
	11.	Percent of Class Represented by Amount in Row 94.67%(2)
	12.	Type of Reporting Person (See Instructions) CO

(1)

Voting and investment power over the shares held by HBM Healthcare Investments (Cayman) Ltd. is exercised by the board of directors of HBM Healthcare Investments (Cayman) Ltd. The board of directors of HBM Healthcare Investments (Cayman) Ltd. consists of Jean Marc Lesieur, Sophia Harris, Richard Coles, Dr. Andreas Wicki and Paul Woodhouse, none of whom has individual voting or investment power with respect to the shares.

(2)

This percentage is based upon 20,173,740 shares of the Issuer’s Common Stock, par value $0.001 per share (“Shares”), as set forth in the Issuer’s 10-K, dated March 8, 2017, and filed with the Securities and Exchange Commission on March 8, 2017 .

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Item 1(a).		Name of Issuer: AnaptysBio, Inc.
Item 1(b).		Address of Issuer’s Principal Executive Offices: 10421 Pacific Center Ct., Ste. 200 San Diego, CA 92121
Item 2(a).		Name of Person Filing: HBM Healthcare Investments (Cayman) Ltd.
Item 2(b).		Address of Principal Business Office or, if none, Residence: Governors Square Suite #4-212-2 23 Lime Tree Bay Avenue West Bay Grand Cayman, Cayman Islands
Item 2(c).		Citizenship: Cayman Islands, British West Indies
Item 2(d).		Title of Class of Securities: Common Stock
Item 2(e).		CUSIP Number: 032724106
Item 3.	If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:
	Not applicable

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Item 4.	Ownership
	(a)	Amount beneficially owned:    942,835(1)
	(b)	Percent of class:    4.67%(2)
	(c)	Number of shares as to which the person has:
		(i)	Sole power to vote or to direct the vote    942,835(1)
		(ii)	Shared power to vote or to direct the vote:     0
		(iii)	Sole power to dispose or to direct the disposition of:    942,835(1)
		(iv)	Shared power to dispose or to direct the disposition of:    0
Item 5.	Ownership of 5 Percent or Less of a Class
If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following  x.
Item 6.	Ownership of More than 5 Percent on Behalf of Another Person
Not applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.
Not applicable
Item 8.	Identification and Classification of Members of the Group
Not applicable
Item 9.	Notice of Dissolution of a Group
Not applicable

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Item 10.	Certification
By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and as not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in conneciton with or as a participant in any transaction having that purpose or effect.

(1)           Voting and investment power over the shares held by HBM Healthcare Investments (Cayman) Ltd. is exercised by the board of directors of HBM Healthcare Investments (Cayman) Ltd. The board of directors of HBM Healthcare Investments (Cayman) Ltd. consists of Jean Marc Lesieur, Sophia Harris, Richard Coles, Dr. Andreas Wicki and Paul Woodhouse, none of whom has individual voting or investment power with respect to the shares.

(2)           This percentage is based upon 20,173,740  shares of the Issuer’s Common Stock, par value $0.001 per share (“Shares”), as set forth in  the Issuer’s 10-K, dated March 8, 2017, and filed with the Securities and Exchange Commission on March 8, 2017.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

March 13, 2017
HBM HEALTHCARE INVESTMENTS (CAYMAN) LTD.
By:	/s/Jean-Marc Lesieur
	Jean-Marc Lesieur
	Director

	ATTENTION:
Intentional misstatements or omissions of fact constitute Federal Criminal Violations (See 18 U.S.C. 1001)

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