Ridgeback Capital Investments SC 13G BICYCLE THERAPEUTICS / Ridgeback Capital Investments ownership change

Exhibit 99.1

JOINT FILING AGREEMENT

The undersigned hereby agree that statements on Schedules 13G and/or 13D and Forms 3, 4 and 5 with respect to the securities of Bicycle Therapeutics plc and any amendments thereto signed by each of the undersigned shall be filed on behalf of each of the undersigned pursuant to and in accordance with the provisions of Rule 13d-1(k) promulgated under the Securities Exchange Act of 1934, as amended. The undersigned hereby further agree that this Joint Filing Agreement may be included as an exhibit to such statements or amendments. This Joint Filing Agreement may be executed in any number of counterparts, all of which taken together shall constitute one and the same instrument.

Dated: July 13, 2020

	Ridgeback Capital Investments L.P.
By:	Ridgeback Capital Investments Ltd., Its General Partner
By:	/s/ Bud Holman
	Name: Bud Holman
	Title: Director

	Ridgeback Capital Investments Ltd.
By:	/s/ Bud Holman
	Name: Bud Holman
	Title: Director

	Ridgeback Capital Management LLC
By:	/s/ Bud Holman
	Name: Bud Holman
	Title: Authorized Signatory