Exhibit 99.2
Dear Principians,
We built Principia with one goal in mind: to help patients lead better, healthier lives. We have built an amazing company that has accomplished a lot over the last nine years. Not surprisingly, others have started to pay attention to us.
Today marks an important day in the history of Principia as we announce that Sanofi has expressed its intention to acquire Principia. This proposed merger will bring significant resources to expand and accelerate the potential benefits of these therapies for patients all over the world. The ability to develop several BTK inhibitors will allow us to target specific organ systems for optimal patient benefit. A combination with Sanofi will provide global resources to get these novel therapies to patients. Attached is a copy of the press release announcing the proposed transaction.
Together we have built an incredible company that you should be extremely proud of. Our hard work, combined with our special culture, have produced an enviable portfolio and track record. Our company and therapies are successful because we always focused on science, asked questions and took the risks of breaking new ground to help patients in need. We have a commonality with Sanofi in our endeavor to improve the lives of people with immune mediated diseases.
We have been very successful not only because of what we did scientifically, but how we did it. We pushed boundaries, achieved what seemed impossible and did it in our own, unconventional way. This is the special sauce that has led to the tremendous success of Principia. The proposed merger with Sanofi gives us reach and impact that we cannot have alone. We know rilzabrutinib, PRN473 Topical and PRN2246/SAR442168 have tremendous potential, but to help the greatest number of patients, Sanofi’s global leadership and long, successful track record – not to mention financial resources — will allow them to develop our pipeline and platform to the benefit of many in need.
Looking to next steps, we expect the transaction to close in the fourth quarter of 2020, subject to customary closing conditions and regulatory approvals. We will be making the required filings with the SEC regarding the transaction, and as soon as we have additional information to share, we will be in touch with you. We greatly appreciate your understanding of the situation, as we are limited in what we can communicate at this point, but please rest assured that we will provide you with additional information as the process unfolds.
I know and understand that this announcement will lead to many emotions and feelings and will take some time for all of us to digest. We will feel uncertainty and wonder what the future will bring. In times like this it is important to come back to our first principles, which are to help patients. To do this, I hope we can all focus with intensity on execution and making sure that our projects move forward. Today’s announcement should not have a significant impact on your daily work life, at least for the foreseeable future. Until the closing of the proposed transaction, we will continue to operate as an independent company and will continue to focus on our key objectives for our pipeline and technology platform.
Our unwavering commitment to designing and building therapeutics and a new generation of transformative medicines is what has made this tremendous opportunity possible.
I believe this opportunity is important for all of us and the patients we serve. This was a decision that management and the board of directors did not enter into casually. I would like to thank you for your continued dedication, support, and contribution, particularly over the last year, which has resulted in tremendous progress and success for our company. The success that we have experienced has allowed us to become a pioneer in our industry and has made this transaction possible.