Syros Pharmaceuticals, Inc.
35 CambridgePark Drive, 4th Floor
Cambridge, MA 02140
April 26, 2023
VIA EDGAR SUBMISSION
U.S. Securities and Exchange Commission
Division of Corporation Finance, Office of Life Sciences
100 F Street, N.E.
Washington, D.C. 20549
Attention: James McNamara
| Re: | Syros Pharmaceuticals, Inc. |
Registration Statement on Form S-3
File No. 333-271160
Request for Acceleration
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Syros Pharmaceuticals, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-271160), so that it may become effective at 4:00 p.m., Eastern time, on April 28, 2023, or as soon as practicable thereafter, or at such later time as the Registrant or its counsel may orally request via telephone call to the staff.
Very truly yours, | ||
SYROS PHARMACEUTICALS, INC. | ||
By: | /s/ Gerald Quirk | |
Name: Gerald E. Quirk | ||
Title: Chief Legal Officer | ||
