Exhibit 3.1
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| | DUPLICATE | | Number: BC0712851 |
CERTIFICATE
OF
CHANGE OF NAME
BUSINESS CORPORATIONS ACT
I Hereby Certify that PROTOX THERAPEUTICS INC. changed its name to SOPHIRIS BIO INC. on April 2, 2012 at 12:01 AM Pacific Time.
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 | | Issued under my hand at Victoria, British Columbia On April 2, 2012 
RON TOWNSHEND Registrar of Companies Province of British Columbia Canada |
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 | | Ministry of Finance Corporate and Personal Property Registries | | Number: BC0712851 |
CERTIFICATE
OF
AMALGAMATION
BUSINESS CORPORATIONS ACT
I Hereby Certify that PROTOX THERAPEUTICS INC., incorporation number BC0669876 and 0706490 B.C. LTD., incorporation number C0706490 were amalgamated as one company under the name PROTOX THERAPEUTICS INC. on January 1, 2005 at 12:01 AM Pacific Time.
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| | Issued under my hand at Victoria, British Columbia On January 1, 2005 /s/ JOHN S. POWELL JOHN S. POWELL Registrar of Companies Province of British Columbia Canada | | |
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 | | NUMBER:669876 |
CERTIFICATE
OF
AMALGAMATION
COMPANY ACT
I Hereby CertifythatStratos Biotechnologies Inc., incorporation number 588146,Nucleus Bioscience Inc., incorporation number 591725, andBrightwave Ventures Inc., continuation number C-668948, are amalgamated as one company under the nameSNB CAPITAL CORP.
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| | Issued under my hand at Victoria, British Columbia, on May 20, 2003 /s/ JOHN S. POWELL JOHN S. POWELL Registrar of Companies PROVINCE OF BRITISH COLUMBIA CANADA | | |
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| | Ministry of Finance Corporate and Personal Property Registries | | Number: BC0669876 |
CERTIFICATE
OF
CHANGE OF NAME
BUSINESS CORPORATIONS ACT
I Hereby Certify that SNB CAPITAL CORP. changed its name to PROTOX THERAPEUTICS INC. on July 9, 2004, at 06:32 AM Pacific Time.
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| | Issued under my hand at Victoria, British Columbia On July 9, 2004 /s/ JOHN S. POWELL JOHN S. POWELL Registrar of Companies Province of British Columbia Canada | | |
