Exhibit 12.1
Certification by the Principal Executive Officer pursuant to
Securities Exchange Act Rules13a-14(a) and15d-14(a)
as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
I, André Choulika, certify that:
| 1. | I have reviewed this Amendment No. 1 to Annual Report on Form20-F of Cellectis S.A.; and |
| 2. | Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report. |
Date: April 25, 2019
/s/ André Choulika |
| Name: André Choulika |
| Title: Chief Executive Officer (Principal Executive Officer) |
