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Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
| (1) | Registration Statement (Form S-8 No. 333-248996) pertaining to the Amended and Restated 2015 Equity Incentive Plan, 2020 Equity Incentive Plan, and the 2020 Employee Stock Purchase Plan of Metacrine, Inc., and |
| (2) | Registration Statement (Form S-3 No. 333-260023) of Metacrine, Inc.; |
of our report dated March 30, 2022, with respect to the consolidated financial statements of Metacrine, Inc., included in this Annual Report (Form 10-K) of Metacrine, Inc. for the year ended December 31, 2021.
/s/ Ernst & Young LLP
San Diego, California
March 30, 2022