vTv Therapeutics (VTVT) 10-K 29 Mar 22 2021 FY Annual report Financial data

Document and Entity Information

Document and Entity Information - USD ($)	12 Months Ended
	Dec. 31, 2021	Mar. 29, 2022	Jun. 30, 2021
Document Information [Line Items]
Document Type	10-K
Amendment Flag	false
Document Period End Date	Dec. 31, 2021
Document Fiscal Year Focus	2021
Document Fiscal Period Focus	FY
Trading Symbol	VTVT
Entity Registrant Name	vTv Therapeutics Inc.
Entity Central Index Key	0001641489
Current Fiscal Year End Date	--12-31
Entity Well-known Seasoned Issuer	No
Entity Current Reporting Status	Yes
Entity Voluntary Filers	No
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Shell Company	false
Document Annual Report	true
Document Transition Report	false
Entity File Number	001-37524
Entity Tax Identification Number	47-3916571
Entity Incorporation, State or Country Code	DE
Entity Address, Address Line One	3980 Premier Dr
Entity Address, Address Line Two	Suite 310
Entity Address, Postal Zip Code	27265
Entity Address, City or Town	High Point
Entity Address, State or Province	NC
Entity Public Float			$ 69,158,248
Title of 12(b) Security	Class A Common Stock (Par Value $0.01)
Security Exchange Name	NASDAQ
City Area Code	336
Local Phone Number	841-0300
Entity Interactive Data Current	Yes
ICFR Auditor Attestation Flag	false
Documents Incorporated by Reference	Portions of the registrant’s Definitive Proxy Statement relating to its 2022 Annual Meeting of Stockholders to be filed within 120 days after December 31, 2021, are incorporated by reference into Part III of this Annual Report on Form 10-K where indicated.
Auditor Firm ID	42
Auditor Name	Ernst & Young LLP
Auditor Location	Raleigh, North Carolina
Class A Common Stock [Member]
Document Information [Line Items]
Entity Common Stock, Shares Outstanding		66,942,777
Class B Common Stock [Member]
Document Information [Line Items]
Entity Common Stock, Shares Outstanding		23,093,860

Consolidated Balance Sheets

Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 13,415	$ 5,747
Accounts receivable, net	57	158
Prepaid expenses and other current assets	2,049	939
Current deposits	100	371
Total current assets	15,621	7,215
Property and equipment, net	278	367
Operating lease right-of-use assets	402	482
Long-term investments	9,173	6,725
Total assets	25,474	14,789
Current liabilities:
Accounts payable and accrued expenses	8,023	6,120
Current portion of operating lease liabilities	184	155
Current portion of contract liabilities	35	31
Current portion of notes payable	256	84
Total current liabilities	8,498	6,390
Contract liabilities, net of current portion		1,009
Operating lease liabilities, net of current portion	492	676
Warrant liability, related party	1,262	2,871
Other liabilities		50
Total liabilities	10,252	10,996
Commitments and contingencies
Redeemable noncontrolling interest	24,962	83,895
Stockholders’ deficit:
Additional paid-in capital	238,193	209,161
Accumulated deficit	(248,834)	(290,036)
Total stockholders’ deficit attributable to vTv Therapeutics Inc.	(9,740)	(80,102)
Total liabilities, redeemable noncontrolling interest and stockholders’ deficit	25,474	14,789
Class A Common Stock [Member]
Stockholders’ deficit:
Common stock value	669	541
Class B Common Stock [Member]
Stockholders’ deficit:
Common stock value	$ 232	$ 232

Consolidated Balance Sheets (Pa

Consolidated Balance Sheets (Parenthetical) - $ / shares	Dec. 31, 2021	May 04, 2021	Dec. 31, 2020	Jul. 29, 2015
Class A Common Stock [Member]
Common stock par value	$ 0.01		$ 0.01	$ 0.01
Common stock, shares authorized	200,000,000	200,000,000	100,000,000	100,000,000
Common stock, shares outstanding	66,942,777		54,050,710
Class B Common Stock [Member]
Common stock par value	$ 0.01		$ 0.01	$ 0.01
Common stock, shares authorized	100,000,000		100,000,000	100,000,000
Common stock, shares outstanding	23,093,860		23,094,221

Consolidated Statements of Oper

Consolidated Statements of Operations - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue	$ 4,005,000	$ 6,414,000	$ 2,764,000
Operating expenses:
Research and development	13,324,000	11,015,000	15,119,000
General and administrative	12,343,000	7,251,000	8,537,000
Total operating expenses	25,667,000	18,266,000	23,656,000
Operating loss	(21,662,000)	(11,852,000)	(20,892,000)
Other income	2,448,000		1,000
Other income (expense) – related party	1,609,000	(270,000)	827,000
Interest income	1,000	12,000	53,000
Interest expense	(12,000)	(692,000)	(1,827,000)
Loss before income taxes and noncontrolling interest	(17,616,000)	(12,802,000)	(21,838,000)
Income tax provision	115,000	0	100,000
Net loss before noncontrolling interest	(17,731,000)	(12,802,000)	(21,938,000)
Less: net loss attributable to noncontrolling interest	(4,744,000)	(4,303,000)	(8,894,000)
Net loss attributable to vTv Therapeutics Inc.	(12,987,000)	(8,499,000)	(13,044,000)
Net loss attributable to vTv Therapeutics Inc. common shareholders	$ (12,987,000)	$ (8,499,000)	$ (17,913,000)
Class A Common Stock [Member]
Operating expenses:
Net loss per share of vTv Therapeutics Inc. Class A Common Stock, basic and diluted	$ (0.21)	$ (0.18)	$ (0.59)
Weighted average number of vTv Therapeutics Inc. Class A Common Stock, basic and diluted	60,732,636	47,137,917	30,292,030

Consolidated Statements of Chan

Consolidated Statements of Changes in Redeemable Noncontrolling Interest and Stockholders' Deficit - USD ($) $ in Thousands	Total	Redeemable Noncontrolling Interest [Member]	Class A Common Stock [Member]	Class B Common Stock [Member]	Common Stock [Member]Class A Common Stock [Member]	Common Stock [Member]Class B Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2018	$ (82,853)				$ 203	$ 232	$ 150,595	$ (233,883)
Beginning balance, redeemable noncontrolling interest at Dec. 31, 2018		$ 62,482
Beginning balance, shares at Dec. 31, 2018					20,347,065	23,094,221
Net loss	(13,044)	(8,894)						(13,044)
Share-based compensation	1,518						1,518
Issuance of Class A Common Stock under registered direct offering	5,443				$ 37		5,406
Issuance of Class A Common Stock under registered direct offering, shares					3,636,364
Issuance of Class A Common Stock to a related party under the Letter Agreements	27,500				$ 169		27,331
Issuance of Class A Common Stock to a related party under the Letter Agreements, shares					16,923,427
Issuance of Letter Agreement and warrants to purchase Class A Common Stock - related party	(992)						(992)
Vesting of restricted stock units, shares					11,666
Change in redemption value of noncontrolling interest		(13,405)
Change in redemption value of noncontrolling interest	13,405							13,405
Ending balance at Dec. 31, 2019	(49,023)				$ 409	$ 232	183,858	(233,522)
Ending balance, redeemable noncontrolling interest at Dec. 31, 2019		40,183
Ending balance, shares at Dec. 31, 2019					40,918,522	23,094,221
Net loss	(8,499)	(4,303)						(8,499)
Share-based compensation	1,009						1,009
Issuance of Class A Common Stock under ATM offering	12,496				$ 55		12,441
Issuance of Class A common stock under ATM offering shares					5,480,941
Issuance of Class A Common Stock to a related party under the Letter Agreements	10,000				$ 63		9,937
Issuance of Class A Common Stock to a related party under the Letter Agreements, shares					6,250,000
Issuance of Class A Common Stock under LPC Agreement	1,930				$ 14		1,916
Issuance of Class A Common Stock under LPC agreement shares					1,389,580
Vesting of restricted stock units, shares					11,667
Change in redemption value of noncontrolling interest		48,015
Change in redemption value of noncontrolling interest	(48,015)							(48,015)
Ending balance at Dec. 31, 2020	(80,102)				$ 541	$ 232	209,161	(290,036)
Ending balance, redeemable noncontrolling interest at Dec. 31, 2020	83,895	83,895
Ending balance, shares at Dec. 31, 2020			54,050,710	23,094,221	54,050,710	23,094,221
Net loss	(12,987)	(4,744)						(12,987)
Share-based compensation	2,356						2,356
Issuance of Class A Common Stock under ATM offering	17,670				$ 89		17,581
Issuance of Class A common stock under ATM offering shares					8,929,147
Exchange of Class B Common Stock for Class A Common Stock, shares					361	(361)
Exercise of stock options	$ 47						47
Exercise of stock options, shares	20,833				20,833
Issuance of Class A Common Stock under LPC Agreement	$ 9,087				$ 39		9,048
Issuance of Class A Common Stock under LPC agreement shares					3,941,726
Change in redemption value of noncontrolling interest		(54,189)
Change in redemption value of noncontrolling interest	54,189							54,189
Ending balance at Dec. 31, 2021	(9,740)				$ 669	$ 232	$ 238,193	$ (248,834)
Ending balance, redeemable noncontrolling interest at Dec. 31, 2021	$ 24,962	$ 24,962
Ending balance, shares at Dec. 31, 2021			66,942,777	23,093,860	66,942,777	23,093,860

Consolidated Statements of Cash

Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Cash flows from operating activities:
Net loss before noncontrolling interest	$ (17,731)	$ (12,802)	$ (21,938)
Adjustments to reconcile net loss before noncontrolling interest to net cash used in operating activities:
(Gain) on disposal of property and equipment, net			(288)
Depreciation expense	89	94	39
Share-based compensation expense	2,356	1,009	1,518
Change in fair value of investments	(2,448)	(4,245)
Change in fair value of warrants, related party	(1,609)	270	(827)
Amortization of debt discount		380	532
Changes in assets and liabilities:
Accounts receivable	101	(153)	(5)
Prepaid expenses and other assets	(839)	(254)	732
Long-term deposits		444	(408)
Accounts payable and accrued expenses	1,828	(997)	(618)
Accreted interest on debt		(1,512)
Contract liabilities	(1,005)	(24)	(1,755)
Other liabilities	(50)	(210)
Net cash used in operating activities	(19,308)	(18,000)	(23,018)
Cash flows from investing activities:
Proceeds from sale of assets			312
Purchases of property and equipment			(70)
Net cash provided by investing activities			242
Cash flows from financing activities:
Proceeds from issuance of Class A Common Stock to a related party under the Letter Agreements		10,000	27,500
Proceeds from issuance of Class A Common Stock, net of offering costs	26,757	14,426	5,443
Proceeds from exercise of stock options	47
Proceeds from debt issuance	887	500	500
Repayment of notes payable	(715)	(5,456)	(10,573)
Net cash provided by financing activities	26,976	19,470	22,870
Net increase in cash, cash equivalents and restricted cash and cash equivalents	7,668	1,470	94
Total cash, cash equivalents and restricted cash and cash equivalents, beginning of year	5,747	4,277	4,183
Total cash, cash equivalents and restricted cash and cash equivalents, end of year	13,415	5,747	4,277
Supplemental cash flow information:
Cash paid for interest	11	623	1,295
Cash paid for income taxes	115		100
Non-cash activities:
Right-of-use assets obtained in exchange for lease obligations			548
Leasehold improvements obtained in exchange for lease obligations			384
Issuance of Letter Agreements and warrants to purchase vTv Therapeutics Inc. Class A Common Stock to a related party			992
Redeemable Noncontrolling Interest [Member]
Non-cash activities:
Change in redemption value of noncontrolling interest	$ (54,189)	$ 48,015	$ (13,405)

Description of Business and Bas

Description of Business and Basis of Presentation	12 Months Ended
	Dec. 31, 2021
Accounting Policies [Abstract]
Description of Business and Basis of Presentation	Note 1: Description of Business and Basis of Presentation Description of Business vTv Therapeutics Inc. (the “Company,” the “Registrant,” “we” or “us”), was incorporated in the state of Delaware in April 2015. The Company is a clinical stage pharmaceutical company focused on treating metabolic diseases to minimize their long-term complications through end-organ protection. Principles of Consolidation vTv Therapeutics Inc. is a holding company, and its principal asset is a controlling equity interest in vTv Therapeutics LLC (“vTv LLC”), the Company’s principal operating subsidiary, which is a clinical stage biopharmaceutical company engaged in the discovery and development of orally administered small molecule drug candidates to fill significant unmet medical needs. The Company has determined that vTv LLC is a variable-interest entity (“VIE”) for accounting purposes and that vTv Therapeutics Inc. is the primary beneficiary of vTv LLC because (through its managing member interest in vTv LLC and the fact that the senior management of vTv Therapeutics Inc. is also the senior management of vTv LLC) it has the power and benefits to direct all of the activities of vTv LLC, which include those that most significantly impact vTv LLC’s economic performance. vTv Therapeutics Inc. has therefore consolidated vTv LLC’s results pursuant to Accounting Standards Codification Topic 810, “Consolidation” in its Consolidated Financial Statements. Various holders own non-voting interests in vTv LLC, representing a 25.6% economic interest in vTv LLC, effectively restricting vTv Therapeutics Inc.’s interest to 74.4% of vTv LLC’s economic results, subject to increase in the future, should vTv Therapeutics Inc. purchase additional nonvoting common units (“vTv Units”) of vTv LLC or should the holders of vTv Units decide to exchange such units (together with shares of the Company’s Class B common stock, par value $0.01 (“Class B Common Stock”)) for shares of Class A Common Stock (or cash) pursuant to the Exchange Agreement among the Company, vTv LLC and the holders of vTv Units party thereto (the “Exchange Agreement”). vTv Therapeutics Inc. has provided financial and other support to vTv LLC in the form of its purchase of vTv Units with the net proceeds of the IPO in 2015, its agreeing to be a co-borrower under the Venture Loan and Security Agreement (the “Loan Agreement”) with Horizon Technology Finance Corporation and Silicon Valley Bank (together, the “Lenders”) which was entered into in 2016, its entrance into the letter agreements with MacAndrews and Forbes Group LLC (“M&F Group”), a related party and an affiliate of MacAndrews & Forbes Incorporated (together with its affiliates “MacAndrews”), in December 2017, July 2018, December 2018, March 2019, September 2019 and December 2019 (the “Letter Agreements”), the Controlled Equity Offering SM Sales Agreement (the “Sales Agreement”) with Cantor Fitzgerald & Co. (“Cantor Fitzgerald”) (the “ATM Offering”), and the purchase agreement with Lincoln Park Capital Fund, LLC (“ Lincoln Park ”) (the “LPC Purchase Agreement ”) Going Concern and Liquidity To date, the Company has not generated any product revenue and has not achieved profitable operations. The continuing development of our drug candidates will require additional financing. From its inception through December 31, 2021, the Company has funded its operations primarily through a combination of private placements of common and preferred equity, research collaboration agreements, upfront and milestone payments for license agreements, debt and equity financings and the completion of its IPO in August 2015. As of December 31, 2021, the Company had an accumulated deficit of $248.8 million and has generated net losses in each year of its existence. As of December 31, 2021, the Company had cash and cash equivalents of $13.4 million. To meet our future funding requirements into the fourth quarter of 2022, based on our current operating plans, the Company plans to rely primarily on its remaining availability of $37.3 million under our Controlled Equity Offering SM the ability to sell an additional 9,437,376 shares of Class A Common Stock under the LPC Purchase Agreement based on the remaining number of registered shares. However, the ability to use these sources of capital is dependent on a number of factors, including the prevailing market price of and the volume of trading in the Company’s Class A Common Stock. F-8 These conditions raise substantial doubt about the Company’s ability to continue as a going concern. If we are unable to raise additional capital as and when needed, or upon acceptable terms, such failure would have a significant negative impact on our financial condition. The Company’s financial statements have been prepared assuming the Company will continue as a going concern, which contemplates, among other things, the realization of assets and satisfaction of liabilities in the normal course of business. The Consolidated Financial Statements do not include adjustments to reflect the possible future effects on the recoverability and classification of recorded assets or the amounts of liabilities that might be necessary should the Company be unable to continue as a going concern.

Summary of Significant Accounti

Summary of Significant Accounting Policies	12 Months Ended
	Dec. 31, 2021
Accounting Policies [Abstract]
Summary of Significant Accounting Policies	Note 2: Summary of Significant Accounting Policies Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires the Company to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. On an ongoing basis, the Company evaluates its estimates, including those related to the grant date fair value of equity awards, the fair value of warrants to purchase shares of its Class A Common Stock, the fair value of its Class B Common Stock, the useful lives of property and equipment and the fair value of the Company’s debt, among others. The Company bases its estimates on historical experience and on various other assumptions that it believes to be reasonable, the results of which form the basis for making judgments about the carrying value of assets and liabilities. Concentration of Credit Risk Financial instruments that potentially expose the Company to concentrations of credit risk consist principally of cash on deposit with multiple financial institutions. The balances of these cash accounts frequently exceed insured limits. Three customers represented 100% of the revenue earned during the year ended December 31, 2021, and 2020. Four customers represented 100% of the revenue earned during the year ended December 31, 2019. Cash and Cash Equivalents The Company considers any highly liquid investments with an original maturity of three months or less to be cash and cash equivalents. Collaboration Revenue and Accounts Receivable The majority of the Company’s collaboration revenue and accounts receivable relates to its agreements to license certain of its potential drug products for development. See Note 3 for further discussion of the Company’s collaboration agreements. Accounts receivable are stated at net realizable value. On a periodic basis, the Company evaluates its accounts receivable and establishes an allowance based on its history of collections and write-offs and the current status of all receivables. Property and Equipment and other Long-lived Assets The Company records property and equipment at cost less accumulated depreciation. Costs of renewals and improvements that extend the useful lives of the assets are capitalized. Maintenance and repairs are expensed as incurred. Depreciation is determined on a straight-line basis over the estimated useful lives of the assets, which generally range from three to ten years. Leasehold improvements are depreciated over the shorter of the useful life of the asset or the term of the related lease. Upon retirement or disposition of assets, the costs and related accumulated depreciation are removed from the accounts with the resulting gains or losses, if any, reflected in results of operations. F-9 The estimated useful lives of property and equipment are as follows: Asset Category Useful Life (in years) Laboratory equipment 7 Computers and hardware 3-5 Furniture and office equipment 3-7 Software 3 Leasehold improvements Shorter of useful life or remaining term of lease The Company periodically assesses it property and equipment and other long-lived assets for impairment in accordance with the relevant accounting guidance. No such charges were recognized during the years ended December 31, 2021, 2020 or 2019. There were no assets held for sale at December 31, 2021, or 2020. Investments Investments in entities in which the Company has no control or significant influence, is not the primary beneficiary, and have a readily determinable fair value are classified as equity investments with readily determinable fair value. The investments are measured at fair value based on a quoted market price per unit in active markets multiplied by the number of units held without consideration of transaction costs (Level 1). Gains and losses are recorded in other income (expense), net on the Consolidated Statements of Operations. Equity investments without readily determinable fair value include ownership rights that do not provide the Company with control or significant influence and these investments do not have readily determinable fair values. The Company has elected to measure its equity investments without readily determinable fair values at cost minus impairment, if any, plus or minus changes resulting from observable price changes in orderly transactions for the identical or similar investment . Revenue Recognition The Company uses the revenue recognition guidance established by ASC Topic 606, “Revenue From Contracts With Customers” (“ASC Topic 606”). The majority of the Company’s revenue results from its license and collaboration agreements associated with the development of investigational drug products. The Company accounts for a contract when it has approval and commitment from both parties, the rights of the parties are identified, payment terms are identified, the contract has commercial substance and collectability of consideration is probable. The transaction price under the contract is determined based on the value of the consideration expected to be received in exchange for the transferred assets or services. Development, regulatory and sales milestones included in the Company’s collaboration agreements are considered to be variable consideration. The amount of variable consideration expected to be received is included in the transaction price when it becomes probable that the milestone will be met. For contracts with multiple performance obligations, the contract’s transaction price is allocated to each performance obligation using the Company’s best estimate of the standalone selling price of each distinct good or service in the contract. The primary method used to estimate standalone selling price is the expected cost plus margin approach. Revenue is recognized over the related period over which the Company expects the services to be provided using a proportional performance model or a straight-line method of recognition if there is no discernable pattern over which the services will be provided. F-10 Fair Value of Financial Instruments The Company uses a three-tier fair value hierarchy to classify and disclose all assets and liabilities measured at fair value on a recurring basis, as well as assets and liabilities measured at fair value on a non-recurring basis, in periods subsequent to their initial measurement. The hierarchy requires the Company to use observable inputs when available, and to minimize the use of unobservable inputs, when determining fair value. The three tiers are defined as follows: • Level 1—Observable inputs that reflect quoted market prices (unadjusted) for identical assets or liabilities in active markets; • Level 2—Observable inputs other than quoted prices in active markets that are observable either directly or indirectly in the marketplace for identical or similar assets and liabilities; and • Level 3—Unobservable inputs that are supported by little or no market data, which require the Company to develop its own assumptions. Research and Development Major components of research and development costs include cash compensation, depreciation expense on research and development property and equipment, costs of preclinical studies, clinical trials and related clinical manufacturing, costs of drug development, costs of materials and supplies, facilities cost, overhead costs, regulatory and compliance costs, and fees paid to consultants and other entities that conduct certain research and development activities on the Company’s behalf. Research and development costs are expensed as incurred. The Company records accruals based on estimates of the services received, efforts expended and amounts owed pursuant to contracts with numerous contract research and manufacturing organizations. In the normal course of business, the Company contracts with third parties to perform various clinical study activities in the ongoing development of potential products. The financial terms of these agreements are subject to negotiation and variation from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events and the completion of portions of the clinical study or similar conditions. The objective of the Company’s accrual policy is to match the recording of expenses in its financial statements to the actual services received and efforts expended. As such, expense accruals related to clinical studies are recognized based on the Company’s estimate of the degree of completion of the event or events specified in the specific clinical study. The Company records nonrefundable advance payments it makes for future research and development activities as prepaid expenses. Prepaid expenses are recognized as expense in the Consolidated Statements of Operations as the Company receives the related goods or services. Research and development costs that are reimbursed under a cost-sharing arrangement are reflected as a reduction of research and development expense. Patent Costs Patent costs, including related legal costs, are expensed as incurred and recorded within general and administrative operating expenses on the Consolidated Statements of Operations. Income Taxes From its formation on August 1, 2015, vTv Therapeutics Inc. has been subject to corporate level income taxes. Prior to July 30, 2015, the Company’s predecessor entities were taxed as partnerships and all their income and deductions flowed through and were subject to tax at the partner level. vTv Therapeutics Inc. is required to recognize deferred tax assets and liabilities for the difference between the financial reporting and tax basis of its investment in vTv LLC. The Company’s income tax expense, deferred tax assets and liabilities and reserves for unrecognized tax benefits reflect management’s best assessment of estimated future taxes to be paid. The Company is subject to income taxes in both the United States and various state jurisdictions. Significant judgments and estimates are required in determining the consolidated income tax expense. The Company accounts for income taxes under the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events included in the financial statements. Under this method, the Company determines deferred tax assets and liabilities on the basis of differences between the financial statement and tax bases of assets and liabilities by using enacted tax rates in effect for the year in which the differences are expected to reverse. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in income in the period in which the enactment date occurs. F-11 The Company recognizes deferred tax assets to the extent it believes these assets are more-likely-than-not to be realized. In making such a determination, the Company considers all available positive and negative evidence, including future reversals of existing taxable temporary differences, projected future taxable income, tax planning strategies and recent results of operations. The Company records uncertain tax positions on the basis of a two-step process in which (1) it determines whether it is more-likely-than-not that the tax positions will be sustained on the basis of the technical merits of the position and (2) for those tax positions meeting the more-likely-than-not recognition threshold, it recognizes the largest amount of tax benefit that is more than 50% likely to be realized upon ultimate settlement with the related tax authority. Interest and penalties related to income taxes are included in the benefit (provision) for income taxes in the Company’s Consolidated Statements of Operations. The Company has not incurred any significant interest or penalties related to income taxes in any of the periods presented. Noncontrolling Interest The Company records the redeemable noncontrolling interest represented by the vTv Units and the Class B Common stock at the higher of (1) its initial fair value plus accumulated earnings/losses associated with the noncontrolling interest or (2) the redemption value as of the balance sheet date. See discussion and additional detail of the redeemable noncontrolling interest at Note 13. Segment and Geographic Information Operating segments are defined as an enterprise’s components (business activities from which it earns revenue and incurs expenses) for which discrete financial information is (1) available; and (2) is regularly reviewed by the chief operating decision maker (“CODM”) in deciding how to allocate resources and in assessing performance. The Company’s CODM is its President and Chief Executive Officer. The Company’s business operates in one reportable segment comprised of one operating segment. Leases The Company determines if an arrangement is a lease at inception. Balances recognized related to operating leases are included in operating lease right-of-use assets and operating lease liabilities in the Consolidated Balance Sheets. Operating lease right-of-use assets and operating lease liabilities are recognized based on the present value of the future minimum lease payments over the lease term at commencement date. Lease terms may include options to extend of terminate the lease if it is reasonably certain that the Company will exercise the option. As most of the Company’s leases do not provide an implicit rate, the Company uses its incremental borrowing rate based on the information available at the commencement date in determining the present value of future payments. The operating lease right-of-use asset also includes any lease payments made and excludes lease incentives and initial direct costs incurred. The Company has elected a practical expedient to not separate its lease and non-lease components and instead account for them as a single lease component. Lease expense for minimum lease payments is recognized on a straight-line basis over the lease term. Lease payments for short-term leases are recorded to operating expense on a straight-line basis and variable lease payments are recorded in the period in which the obligation for those payments is incurred. Share-Based Compensation Compensation expense for share-based compensation awards issued is based on the fair value of the award at the date of grant, and compensation expense is recognized for those awards earned over the service period. The grant date fair value of stock option awards is estimated using the Black-Scholes option pricing formula. Expected volatility is based on the historical volatility of the Company’s common stock over the most recent period commensurate with the estimated expected term of the Company’s stock options offering period which is derived from historical experience. In the event the participant’s employment by or engagement with (as a director or otherwise) the Company terminates before exercise of the options granted, the stock options granted to the participant shall immediately expire and all rights to purchase shares there under shall immediately cease and expire and be of no further force or effect, other than applicable exercise rights for vested shares that may extend past the termination date as provided for in the participant’s applicable option award agreement. The Company entered into a retirement agreement with its former CEO Steve Holcombe in October 2021, and separation agreements with certain key employees in December 2021. The retirement and separation agreements provide for accelerated vesting and extend the exercise period for certain outstanding equity awards. F-12 The fair value of restricted stock units (“RSU”) grants are based on the market value of the Class A Common Stock on the date of grant. The Company also estimates the amount of share-based awards that are expected to be forfeited based on historical employee turnover rates. Comprehensive Income The Company does not have any components of other comprehensive income recorded within its Consolidated Financial Statements, and, therefore, does not separately present a statement of comprehensive income in its Consolidated Financial Statements. Recently Issued Accounting Pronouncements There have been no recently issued accounting pronouncements which are expected to have a material impact on the Company’s financial statements.

Collaboration Agreements

Collaboration Agreements	12 Months Ended
	Dec. 31, 2021
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Collaboration Agreements	Note 3: Collaboration Agreements Reneo License Agreement On December 21, 2017, the Company entered into the Reneo License Agreement, under which Reneo obtained an exclusive, worldwide, sublicensable license to develop and commercialize the Company’s peroxisome proliferation activated receptor delta (PPAR- δ HPP593 Pursuant to the terms of the Reneo License Agreement, the Company is required to provide technology transfer services for a defined period after the effective date. In accordance with ASC Topic 606, the Company identified all of the performance obligations at the inception of the Reneo License Agreement. The significant obligations were determined to be the license and the technology transfer services. The Company has determined that the license and technology transfer services represent a single performance obligation because they were not capable of being distinct on their own. The transaction price has been fully allocated to this combined performance obligation. The Company determined that there was no discernable pattern in which the technology services would be provided during the transfer services period. As such, the Company determined that the straight-line method would be used to recognize revenue over the transfer service period. The Company recognized $1.7 million of revenue related to this combined performance obligation for the year ended December 31, 2019. As of December 31, 2019, revenue allocated to this performance obligation had been fully recognized. During the year ended December 31, 2021, $2.0 million of revenue was recognized due to the satisfaction of a development milestone under the license agreement. This amount was fully recognized as revenue during the year ended December 31, 2021, as the related performance obligation was fully satisfied. Huadong License Agreement On December 21, 2017, the Company entered into a License Agreement with Huadong (the “Huadong License Agreement”), under which Huadong obtained an exclusive and sublicensable license to develop and commercialize the Company’s glucagon-like peptide-1 receptor agonist (“GLP-1r”) program, including the compound TTP273 F-13 On January 14, 2021, the Company entered into the First Huadong Amendment which eliminated the Company’s obligation to sponsor a Prior to the First Amendment, the Company had allocated a portion of the transaction price to the obligation to sponsor and conduct a portion of the Phase 2 MRCT. Upon the removal of this performance obligation, the Company evaluated the impact of the modification under the provisions of ASC Topic 606 and performed a reallocation of the transaction price among the remaining performance obligations. This resulted in the recognition of approximately $1.0 million of revenue on a cumulative catch up basis during the year ended December 31, 2021. The majority of the transaction price originally allocated to the Phase 2 MRCT performance obligation was reallocated to the license and technology transfer services combined performance obligation discussed below, which had already been completed. The reallocation of the purchase price in connection with the First Huadong Amendment was made based on the relative estimated selling prices of the remaining performance obligations. The significant performance obligations under this license agreement, as amended, were determined to be (i) the exclusive license to develop and commercialize the Company’s GLP-1r program, (ii) technology transfer services related to the chemistry and manufacturing know-how for a defined period after the effective date, (iii) the Company’s obligation to participate on a joint development committee (the “JDC”), and (iv) other obligations considered to be de minimis in nature. The Company has determined that the license and technology transfer services related to the chemistry and manufacturing know-how represent a combined performance obligation because they were not capable of being distinct on their own. The Company also determined that there was no discernable pattern in which the technology transfer services would be provided during the transfer service period. As such, the Company recognized the revenue related to this combined performance obligation using the straight-line method over the transfer service period. This combined performance obligation was considered complete as of December 31, 2018. In connection with the First Huadong Amendment, the Company recognized approximately $1.0 million of revenue related to this performance obligation during the year ended December 31, 2021 due to the reallocation of the transaction price among the performance obligations remaining after the First Huadong Amendment. The Company also determined that the obligation to participate in the joint development committee (the “JDC”) to oversee the development of products should be treated as a separate performance obligation. A portion of the total consideration received under the Huadong License Agreement was allocated to this performance obligation based on its estimated standalone selling price. A portion of this amount remains deferred as of December 31, 2021, and revenue will be recognized using the proportional performance model over the period of the Company’s participation on the JDC. The unrecognized amount of the transaction price allocated to this performance obligation as of December 31, 2021, was $0.1 million. An immaterial amount of revenue was recognized for this performance obligation for the years ended December 31, 2021, 2020 and 2019. The remaining milestone payments that the Company is eligible to receive have not been included in the transaction price as of December 31, 2021, as it is not considered probable that such payments will be received. Newsoara License Agreement On May 31, 2018, the Company entered into a license agreement with (“Newsoara”) (the “Newsoara License Agreement”) phosphodiesterase type 4 inhibitors (“PDE4”) program, including the compound HPP737 , in China and other Pacific Rim territories Pursuant to the terms of the Newsoara License Agreement, the Company is required to provide technology transfer services for a defined period after the effective date. In accordance with ASC Topic 606, the Company identified all of the performance obligations at the inception of the Newsoara License Agreement. The significant obligations were determined to be the license and the technology transfer services. The Company has determined that the license and technology transfer services represent a single performance obligation because they were not capable of being distinct on their own. The transaction price has been fully allocated to this combined performance obligation and the related revenue was recognized during the year ended December 31, 2018. F-14 During each of the year s ended December 31, 2021 , and 2019 , the transaction price for this performance obligation was increased by $ 1.0 million due to the satisfaction of development milestone s under the license agreement. Th ese amount s w ere fully recognized as revenue during the year s ended December 31, 2021 , and 2019 , as the related performance obligation s ha ve been fully satisfied . The remaining milestone payments that the Company is eligible to receive have not been included in the transaction price as of December 31, 2021, as it is not considered probable that such payments will be received. Anteris License Agreement On December 11, 2020, the Company entered into a license agreement with Anteris Bio, Inc. (“Anteris”) (the “Anteris License Agreement”) HPP971 Under the terms of the Anteris License Agreement, Anteris paid the Company an initial license fee of $2.0 million. The Company is eligible to receive additional potential development, regulatory, and sales-based milestone payments totaling up to $151.0 million. Anteris is also obligated to pay vTv royalty payments at a double-digit rate based on annual net sales of licensed products. Such royalties will be payable on a licensed product-by-licensed product basis until the latest of expiration of the licensed patents covering a licensed product in a country, expiration of data exclusivity rights for a licensed product in a country, or a specified number of years after the first commercial sale of a licensed product in a country. As additional consideration, the Company received preferred stock representing a minority ownership interest in Anteris. Pursuant to the terms of the Anteris License Agreement, the Company was required to provide technology transfer services for a 30 day period after the effective date. In accordance with ASC Topic 606, the Company identified all of the performance obligations at the inception of the Anteris License Agreement. The significant obligations were determined to be the license and the technology transfer services. The Company has determined that the license and technology transfer services represent a single performance obligation because they were not capable of being distinct on their own. The transaction price has been fully allocated to this combined performance obligation and consisted of the $2.0 million initial license payment as well as the fair value of the equity interest received in Anteris of $4.2 million. The revenue related to this performance obligation was fully recognized during the year ended December 31, 2020, as the technology transfer services were considered complete as of that date. No revenue was recognized related to the Anteris License Agreement during the year ended December 31, 2021. JDRF Agreement In August 2017, the Company entered into the JDRF Agreement to support the funding of the Simplici-T1 Study, an adaptive Phase 1b/2 study to explore the effects of TTP399 The JDRF Agreement was amended in June 2021 to provide additional funding for the Company’s mechanistic study exploring the effects of TTP399 on ketone body formation during a period of insulin withdrawal in people with type 1 diabetes. According to the terms of the JDRF Agreement, as amended, JDRF will provide research funding of up to $3.4 million based on the achievement of research and development milestones, with the total funding provided by JDRF not to exceed approximately one-half TTP399 Payments that the Company receives from JDRF under this agreement are recorded as restricted cash and current liabilities and recognized as an offset to research and development expense, based on the progress of the project, and only to the extent that the restricted cash is utilized to fund such development activities. As of December 31, 2021, the Company had received funding under this agreement of $3.4 million, and research and development costs were offset by $3.4 million. Contract Liabilities Contract liabilities related to the Company’s collaboration agreements consisted of the following (in thousands): December 31, 2021 December 31, 2020 Current portion of contract liabilities $ 35 $ 31 Contract liabilities, net of current portion — 1,009 Total contract liabilities $ 35 $ 1,040 F-15 The change in the Company’s contract liabilities for the year ended December 31, 2021, was due to the recognition of amounts included in the contract liability at the beginning of the period caused by the reallocation of the transaction price in connection with the First Huandong Amendment discussed above.

Share-Based Compensation

Share-Based Compensation	12 Months Ended
	Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Share-Based Compensation	Note 4: Share-Based Compensation In conjunction with the Company’s initial public offering (“IPO”), the board of directors of vTv Therapeutics Inc. (the “Board of Directors”) and sole stockholder adopted a long-term equity incentive plan, the vTv Therapeutics Inc. 2015 Omnibus Equity Incentive Plan (the “Plan”). The Plan provides for the grant of stock options, restricted stock, restricted stock units and other awards based on our Class A Common Stock to management, other key employees, consultants and non-employee directors on terms and subject to conditions as established by our Compensation Committee. In settlement of its obligations under this plan, the Company will issue new shares of Class A Common Stock. Following an amendment to increase the number of shares available under the plan in 2020, the maximum number of shares of the Company’s Class A Common Stock that has been approved and may be subject to awards under the Plan is 7.0 million, subject to adjustment in accordance with terms of the Plan. The Company has issued non-qualified stock option awards and restricted stock units to certain employees, consultants and non-employee directors of the Company. These awards generally vest ratably over a three-year The Company entered into a retirement agreement on October 19, 2021, with its former CEO Steve Holcombe which included provisions for him to retire from full-time service as CEO as of October 19, 2021. As part of the retirement agreement, Mr. Holcombe’s remaining unvested awards will continue to vest and be fully vested on December 31, 2022. In light of this change, the Company entered into an employment and Inducement Agreement with Deepa Prasad, who was appointed President and CEO as of October 19, 2021. The Inducement Agreement provided the grant of 2,498,635 options to purchase the Company's Class A common stock at a strike price of $1.47 per share. The grants have varying service and performance vesting requirements depending on the grantee's status as an employee. The awards subject to the Inducement Agreement were not charged against the Plan’s share reserve and are being granted outside of the Plan as an Inducement Award. The Company also entered into separation agreements with several other key employees in December 2021 who had a combination of unvested and vested stock options at the termination date. As a result of the retirement and separation agreements, 1,190,263 stock options to purchase shares of common stock were modified to increase the time period to exercise the options and 616,667 stock options to purchase shares of common stock were modified to accelerate vesting at the termination date. Additionally, 375,000 stock options were canceled for the year ended December 31, 2021, related to the separation agreements. The Company incurred $0.5 million of additional stock compensation expense for the modifications for the year ended December 31, 2021. The aggregate intrinsic value of the in-the-money awards outstanding as well as those exercisable as of December 31, 2021, was an insignificant amount. The Company uses the Black-Scholes option pricing model to calculate the fair value of stock options granted. The fair value of stock options granted was estimated using the following assumptions during the years ended December 31, 2021, 2020 and 2019: For the Year Ended December 31, 2021 2020 2019 Expected volatility 118.75% - 122.17% 120.37% - 121.43% 115.29% - 120.15% Expected life of option, in years 5.8 - 6.0 5.7 - 6.0 5.3 - 6.0 Risk-free interest rate 1.00% - 1.34% 0.39% - 0.53% 1.58% - 2.64% Expected dividend yield 0.00% 0.00% 0.00% F-16 The following table summarizes the activity related to the stock option awards for the year ended December 31, 2021 (in thousands, except per share amounts): Number of Shares Weighted Average Exercise Price Awards outstanding at December 31, 2020 4,453,357 $ 4.41 Granted 3,368,635 1.43 Exercised (20,833 ) 2.24 Forfeited (745,124 ) 2.60 Awards outstanding at December 31, 2021 7,056,035 $ 3.19 Options exercisable at December 31, 2021 2,908,180 $ 5.50 Weighted average remaining contractual term 6.3 Years Options vested and expected to vest at December 31, 2021 5,960,235 $ 3.50 Weighted average remaining contractual term 7.9 Years Compensation expense related to the grants of stock options is included in research and development and general and administrative expense as follows (in thousands): 2021 2020 2019 Research and development $ 599 $ 348 $ 522 General and administrative 1,757 661 996 Total share-based compensation expense $ 2,356 $ 1,009 $ 1,518

Prepaid Expenses and Other Curr

Prepaid Expenses and Other Current Assets	12 Months Ended
	Dec. 31, 2021
Prepaid Expense And Other Assets Current [Abstract]
Prepaid Expenses and Other Current Assets	Note 5: Prepaid Expenses and Other Current Assets Prepaid expenses and other current assets consist of the following (in thousands): December 31, 2021 2020 Prepaid insurance $ 863 $ 771 Prepaid taxes 97 129 Deferred financing costs 135 — Prepaid - other 954 39 Total $ 2,049 $ 939

Property and Equipment

Property and Equipment	12 Months Ended
	Dec. 31, 2021
Property Plant And Equipment [Abstract]
Property and Equipment	Note 6: Property and Equipment Property and equipment consists of the following (in thousands): December 31, 2021 2020 Leasehold improvements $ 406 $ 406 Computers and hardware 48 48 Software 80 80 Furniture and office equipment 49 49 Total property and equipment 583 583 Less: accumulated depreciation and amortization (305 ) (216 ) Property and equipment, net $ 278 $ 367 Depreciation expense was $0.1

Investments

Investments	12 Months Ended
	Dec. 31, 2021
Investments Debt And Equity Securities [Abstract]
Investments	F-17 Note 7: Investments In connection with the Reneo and Anteris License Agreements, the Company has received equity ownership interests of less than of the voting equity of the investee. Further, the Company does not have the ability to exercise significant influence over the investees. Reneo completed its initial public offering in April 2021. Prior to Reneo becoming a publicly-traded company, the Company’s investment in Reneo did not have a readily determinable fair value and was measured at cost less impairment, adjusted for any changes in observable prices, under the measurement alternative. Subsequent to Reneo’s initial public offering, the Company’s investment in Reneo is considered to have a readily determinable fair value and, as such, is adjusted to its fair value each period with changes in fair value recognized as a component of net loss. The Company’s investment in Anteris does not have a readily determinable fair value and is measured at cost less impairment, adjusted for any changes in observable prices. T he Company’s investments consist of the following: December 31, 2021 December 31, 2020 Equity investment with readily determinable fair value: Reneo common stock $ 4,928 $ — Equity investment without readily determinable fair values assessed under the measurement alternative: Reneo common stock — 2,480 Anteris preferred stock 4,245 4,245 Total $ 9,173 $ 6,725 The Company received its investment in Anteris preferred stock as consideration under the Anteris License Agreement entered into on December 11, 2020. The fair value of the investment was derived from the transaction prices of other securities sold using a market approach. The investment qualifies as Level 3 under the fair value hierarchy as it was valued using unobservable inputs including volatility and risk-free rate assumptions which were 125.0% and 0.37%, respectively. No adjustments have been made to the value of the Company’s investment in Anteris since its initial measurement either due to impairment or based on observable price changes. The Company recognized an unrealized gain on its investment in Reneo of $2.4 million for the year ended December 31, 2021. These adjustments were recognized as a component of other (expense) income in the Company’s Consolidated Statements of Operations.

Accounts Payable and Accrued Ex

Accounts Payable and Accrued Expenses	12 Months Ended
	Dec. 31, 2021
Payables And Accruals [Abstract]
Accounts Payable and Accrued Expenses	Note 8: Accounts Payable and Accrued Expenses Accounts payable and accrued expenses consist of the following (in thousands): December 31, 2021 2020 Accounts payable $ 1,876 $ 1,925 Accrued development costs 2,790 2,581 Accrued compensation and related costs 3,202 1,594 Accrued other 155 20 Total $ 8,023 $ 6,120

Leases

Leases	12 Months Ended
	Dec. 31, 2021
Leases [Abstract]
Leases	Note 9: Leases In August 2019, the Company leased new office space for its headquarters location under an operating lease. This lease commenced in November 2019 after the completion of certain tenant improvements made by the lessor. The lease includes an option to renew for a five-year term as well as an option to terminate after three years, neither of which have been recognized as part of its related right of use assets or lease liabilities as their election is not considered reasonably certain. Further, this lease does not include any material residual value guarantee or restrictive covenants. At December 31, 2021, and 2020, the weighted average incremental borrowing rate for operating leases held by the Company were 13.1%. At December 31, 2021, and 2020, the weighted average remaining lease terms for the operating leases held by the Company were 3.1 years F-18 Maturities of lease liabilities for the Company’s operating leases as of December 31, 2021, were as follows (in thousands): 2022 $ 261 2023 268 2024 275 2025 23 2026 — Thereafter — Total lease payments 827 Less: imputed interest (151 ) Present value of lease liabilities $ 676 Operating lease cost was $0.2 million, $0.2 million and $0.4 million for the years ended December 31, 2021, 2020 and 2019, respectively. During the year ended December 31, 2021, cash paid for operating leases was $0.3 million. The Company had recognized an asset retirement obligation for an obligation in its former facility lease, which expired in December 2019, that required the Company to return the property to the same or similar condition at the end of the lease as existed when the Company began using the facility. As no amounts were required to be paid upon exit of the lease, the asset retirement obligation of $ 0.3 million was reversed during the year ended December 31, 2020.

Notes Payable

Notes Payable	12 Months Ended
	Dec. 31, 2021
Debt Disclosure [Abstract]
Notes Payable	Note 10: Notes Payable Notes payable consist of the following (in thousands): December 31, 2021 December 31, 2020 Notes payable under the Loan Agreement $ — $ — Short-term financing 256 84 Total notes payable 256 84 Less: Current portion (256 ) (84 ) Total notes payable, net of current portion $ — $ — In October 2016, the Company entered into the Loan Agreement with Horizon Technology Finance Corporation and Silicon Valley Bank, under which the Company and vTv LLC borrowed $20.0 million. On April 1, 2020, the Company entered into an amendment to the Loan Agreement (the “Second Amendment”) and on July 29, 2020, the Company entered into the Third Amendment to the Loan Agreement. These amendments extended the maturity dates of the loans and adjusted the minimum cash balance requirements and their impacts have been incorporated into these disclosures and are more fully described below. Each loan tranche bore interest at a floating rate equal to 10.5% plus the amount by which the one-month LIBOR exceeds 0.5%. The Company borrowed the first tranche of $12.5 million upon close of the Loan Agreement in October 2016. The first tranche required only monthly interest payments until May 1, 2018, followed by equal monthly payments of principal plus accrued interest through the scheduled maturity date on May 1, 2020. In connection with the Third Amendment, the maturity date of the first tranche was extended to September 1, 2020. In addition, a final payment for the first tranche loan equal to $0.8 million originally due on May 1, 2020, was extended to September 1, 2020, as part of the Third Amendment, or such earlier date specified in the Loan Agreement. The Company borrowed the second tranche of $7.5 million in March 2017. The second tranche requires only monthly interest payments until October 1, 2018, followed by equal monthly payments of principal plus accrued interest through the scheduled maturity date on October 1, 2020. In connection with the Second Amendment, the maturity date of the second tranche was extended to January 1, 2021. In addition, a final payment for the second tranche loan equal to $0.5 million was originally due on October 1, 2020, or such earlier date specified in the Loan Agreement. In connection with the Second Amendment, the due date for this final payment was extended to January 1, 2021, or such earlier date specified in the Loan Agreement. The total amount of the payment was increased to $0.8 million as a result of the Second and Third Amendments. For each of the first and second tranches, the combined Second and Third Amendment required only monthly interest payments on the outstanding principal balance for the amounts due from April 1, 2020, through August 1, 2020. F-19 In connection with the Loan Agreement, the Company has issued to the Lenders warrants to purchase shares of the Company’s Class A Common Stock (the “Warrants”). On October 28, 2016, the Company issued Warrants to purchase 152,580 shares of its Class A Common Stock at a per share exercise price of $6.39 per share, which aggregate exercise price represents 6.0% of the principal amount borrowed under the first tranche of the Loan Agreement and 3.0% of the principal amount available under the second tranche of the Loan Agreement. On March 24, 2017, in connection with the funding of the second tranche, the Company issued Warrants to purchase 38,006 shares of its Class A Common Stock at a per share exercise price of $5.92 per share, which aggregate exercise price represents 3.0% of the principal amount of the second tranche of the Loan Agreement. In each instance, the Warrants have an exercise price equal to the lower of (a) the volume weighted average price per share of the Company’s Class A Common Stock, as reported on the principal stock exchange on which the Company’s Class A Common Stock is listed, for 10 trading days prior to the issuance of the applicable Warrants or (b) the closing price of a share of the Company’s Class A Common Stock on the trading day prior to the issuance of the applicable Warrants. The Warrants will expire seven years from their date of issuance. The Company’s obligations under the Loan Agreement were secured by a first priority security interest in substantially all of its assets. As a result of the termination of the STEADFAST Study, the Company granted the Lenders a first priority security interest in all of the Company’s intellectual property, subject to certain limited exceptions. The Company agreed not to pledge or otherwise encumber its intellectual property assets, subject to certain exceptions. Upon full repayment and termination of the Loan Agreement in December 2020, these security interests and pledges have been extinguished. The Loan Agreement included customary affirmative and restrictive covenants, including, but not limited to, restrictions on the payment of dividends or other equity distributions and the incurrence of debt or liens upon the assets of the Company or its subsidiaries. The Loan Agreement The Company recorded interest expense related to the Loan Agreement of $0.7 million and $1.8 million for the years ended December 31, 2020, and 2019, respectively. The Company did not recognize any interest expense related to the Loan Agreement during the year ended December 31, 2021, as the Loan Agreement was paid in full and terminated during December 2020.

Commitments and Contingencies

Commitments and Contingencies	12 Months Ended
	Dec. 31, 2021
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies	Note 11: Commitments and Contingencies Legal Matters From time to time, the Company is involved in various legal proceedings arising in the normal course of business. If a specific contingent liability is determined to be probable and can be reasonably estimated, the Company accrues and discloses the amount. The Company is not currently a party to any material legal proceedings. Novo Nordisk In February 2007, the Company entered into an Agreement Concerning Glucokinase Activator Project with Novo Nordisk A/S (the “Novo License Agreement”) whereby the Company obtained an exclusive, worldwide, sublicensable license under certain Novo Nordisk intellectual property rights to discover, develop, manufacture, have manufactured, use and commercialize products for the prevention, treatment, control, mitigation or palliation of human or animal diseases or conditions. As part of this license grant, the Company obtained certain worldwide rights to Novo Nordisk’s GKA program, including rights to preclinical and clinical compounds such as TTP399 TTP399

Stockholders' Equity

Stockholders' Equity	12 Months Ended
	Dec. 31, 2021
Equity [Abstract]
Stockholders' Equity	Note 12: Stockholders’ Equity On July 29, 2015, the Company amended and restated its certificate of incorporation to authorize 100,000,000 shares of Class A Common Stock, 100,000,000 shares of Class B Common Stock and 50,000,000 shares of preferred stock, par value $0.01 per share. On May 4, 2021, the Company filed an amendment to its Amended and Restated Certificate of Incorporation (the “Charter Amendment”) to increase the number of shares of Class A Common Stock that the Company is authorized to issue from F-20 which includes Class A Common Stock and Class B Common Stock, from 200,000,000 to 300,000,000 , and a corresponding increase in the total authorized capital stock, which includes Common Stock and preferred stock, from 250,000,000 shares to 350,000,000 shares. Holders of Class A Common Stock and Class B Common Stock will be entitled to one vote for each share held on all matters submitted to stockholders for their vote or approval. The holders of Class A Common Stock and Class B Common Stock will vote together as a single class on all matters submitted to stockholders for their vote or approval, except with respect to the amendment of certain provisions of the Company’s amended and restated certificate of incorporation that would alter or change the powers, preferences or special rights of the Class B Common Stock so as to affect them adversely, which amendments must be approved by a majority of the votes entitled to be cast by the holders of the shares affected by the amendment, voting as a separate class, or as otherwise required by applicable law. The voting power of the outstanding Class B Common Stock (expressed as a percentage of the total voting power of all common stock) will be equal to the percentage of vTv Units not held by the Company. Holders of Class B Common Stock are not entitled to receive dividends and will not be entitled to receive any distributions upon the liquidation, dissolution or winding up of the Company. ATM Offering In April 2020, the Company entered into the Sales Agreement with Cantor as the sales agent, pursuant to which the Company may offer and sell, from time to time, through Cantor, shares of its Class A common stock, par value $0.01 per share, having an aggregate offering price of up to $13.0 million by any method deemed to be an “at the market offering” as defined in Rule 415(a)(4) under the Securities Act (the “ATM Offering”). The shares are offered and sold pursuant to the Company’s shelf registration statement on Form S-3. On January 14, 2021, and June 25, 2021, the Company filed a prospectus supplement in connection with the ATM Offering to increase the size of the at-the-market offering pursuant to which the Company may offer and sell, from time to time, through or to Cantor, as sales agent or principal, shares of the Company’s Class A Common Stock, by an aggregate offering price of $5.5 million and $50.0 million, respectively. During the years ended December 31, 2021, and 2020, the Company sold 8,929,147 shares and 5,480,941 shares of Class A common stock under the ATM Offering at then-market prices for total gross proceeds of approximately $18.2 million and $13.0 million, respectively. After offering costs and sales commissions owed in connection with the ATM Offering, the Company’s aggregate net proceeds for the years ended December 31, 2021, and 2020 were approximately $17.7 million and $12.5 million, respectively. Lincoln Park Capital Transaction On November 24, 2020, the Company entered into the LPC Purchase Agreement and a registration rights agreement (the “Registration Rights Agreement”), pursuant to which the Company has the right to sell to Lincoln Park shares of the Company’s Class A common stock having an aggregate value of up to $47.0 million, subject to certain limitations and conditions set forth in the LPC Purchase Agreement. The Company will control the timing and amount of any sales of shares to Lincoln Park. pursuant to the Purchase Agreement. The Company filed a registration statement to register As a result, on November 24, 2020, 425,725 newly issued shares of the Company’s common stock, equal to 1.5% percent of the $47.0 million availability, were issued to Lincoln Park as consideration for Lincoln Park’s commitment to purchase shares of the Company’s Class A common stock under the agreement. Upon effectiveness of the registration statement, 963,855 newly issued shares of Class A common stock, valued at $2.08 per share, were sold to Lincoln Park in an initial purchase for an aggregate gross purchase price of $2.0 million in 2020. During 2021, 3,941,726 shares of Class A common stock were sold to Lincoln Park for an aggregate gross purchase price of $9.1 million. Over the 36-month term of the LPC Purchase Agreement, for up to an aggregate amount of $47,000,000 of shares of Class A common stock (subject to certain limitations and conditions), the Company has the right, but not the obligation, from time to time, in its sole discretion, to direct Lincoln Park to purchase up to 250,000 shares per day (the “Regular Purchase Share Limit”) of the Class A common stock (each such purchase, a “Regular Purchase”). The Regular Purchase Share Limit will increase to 275,000 shares per day if the closing price of the Class A common stock on the applicable purchase date is not below $4.00 per share and will further increase to 300,000 shares per day if the closing price of the Class A common stock on the applicable purchase date is not below $5.00 per share. In any case, Lincoln Park’s maximum obligation under any single Regular Purchase will not exceed $2,000,000. The purchase price for shares of Class A common stock to be purchased by Lincoln Park under a Regular Purchase will be equal to the lower of (in each case, subject to the adjustments described in the LPC Purchase Agreement): (i) the lowest sale price for the Class A common stock on the applicable purchase date and (ii) the arithmetic average of the three lowest closing sales prices for the Class A common stock during the 10 consecutive trading days prior to the purchase date. F-21 If the Company directs Lincoln Park to purchase the maximum number of shares of Class A common stock that the Company may sell in a Regular Purchase, then in addition to such Regular Purchase, and subject to certain conditions and limitations in the LPC Purchase Agreement, the Company may direct Lincoln Park to make an “accelerated purchase” and an “additional accelerated purchase”, each of an additional number of shares of Class A common stock which may not exceed the lesser of: (i) 300% of the number of shares purchased pursuant to the corresponding Regular Purchase and (ii) 30% of the total number of shares of the Common Stock traded during a specified period on the applicable purchase date as set forth in the LPC Purchase Agreement. The purchase price for such shares will be the lesser of (i) 97% of the volume weighted average price of the Class A common stock over a certain portion of the date of sale as set forth in the LPC Purchase Agreement and (ii) the closing sale price of the Class A common Stock on the date of sale (an “Accelerated Purchase”). Under certain circumstances and in accordance with the LPC Purchase Agreement, the Company may direct Lincoln Park to purchase shares in multiple Accelerated Purchases on the same trading day. The LPC Purchase Agreement also prohibits the Company from directing Lincoln Park to purchase any shares of its Class A common stock if those shares, when aggregated with all other shares of Class A common stock then beneficially owned by Lincoln Park and its affiliates, would result in Lincoln Park and its affiliates having beneficial ownership, at any single point in time, of more than 9.99% of the then total outstanding shares of Class A common stock as calculated pursuant to Section 13(d) of the Securities Exchange Act of 1934, as amended, and Rule 13d-3 thereunder. Under applicable rules of the Nasdaq Global Select Market, the Company may not issue or sell to Lincoln Park under the LPC Purchase Agreement more than 19.99% of the shares of the Class A common stock outstanding immediately prior to the execution of the LPC Purchase Agreement (the “Exchange Cap”) (or 14,768,682 shares, based on 73,880,351 shares outstanding immediately prior to the execution of the LPC Purchase Agreement), unless (i) stockholder approval is obtained or (ii) the issuances and sales of Class A common stock pursuant to the LPC Purchase Agreement are not deemed to be “below market” in accordance with the applicable rules of Nasdaq. The LPC Purchase Agreement does not limit the Company’s ability to raise capital from other sources at its sole discretion, except that, subject to certain exceptions, the Company may not enter into another “equity line” or similar transaction. The LPC Purchase Agreement and Registration Rights Agreement each contain customary representations, warranties, and agreements of the Company and Lincoln Park, indemnification rights and other obligations of the parties. The offering of Class A common stock pursuant to the LPC Purchase Agreement will terminate on the date that all shares offered by the LPC Purchase Agreement have been sold or, if earlier, the expiration or termination of the LPC Purchase Agreement. The Company has the right to terminate the LPC Purchase Agreement at any time, without fee, penalty or cost to the Company. The net proceeds under the LPC Purchase Agreement to the Company will depend on the frequency and prices at which shares of Class A common stock are sold to Lincoln Park. Actual sales of shares of Class A common stock to Lincoln Park under the LPC Purchase Agreement and the amount of such net proceeds will depend on a variety of factors to be determined by the Company from time to time, including (among others) market conditions, the trading price of the Class A common stock and determinations by the Company as to other available and appropriate sources of funding for the Company. Lincoln Park has covenanted not to cause or engage in any manner whatsoever, any direct or indirect short selling or hedging of Class A common stock. Letter Agreement Warrants The Company has entered into the Letter Agreements with MacAndrews. Under the terms of the Letter Agreements, the Company has or had the right to sell to MacAndrews shares of its Class A Common Stock at a specified price per share , and MacAndrews has or had the right (exercisable up to three times) to require the Company to sell to it shares of Class A Common Stock at the same price. The Letter Agreement Warrants were recorded as warrant liability, related party within the Company’s Consolidated Balance Sheets based on their fair value. The issuance of the Letter Agreement Warrants was considered to be a cost of equity recorded as a reduction to additional paid-in capital. During the years ended December 31, 2021, 2020, and 2019 the Company recognized income/(expense) of $1.6 million, $(0.3) million and $0.8 million, respectively, related to the change in fair value of the Letter Agreement Warrants. These amounts were recognized as a component of other income (expense), related party in the Consolidated Statements of Operations. F-22 Fair value of the Letter Agreement Warrants was calculated as of their issuance date using the methods described in Note 19 using the following assumptions: December 5, 2017 July 30, 2018 December 11, 2018 September 26, 2019 December 23, 2019 Expected volatility 90.00% 95.29% 104.46% 110.35% 110.41% Expected life of option, in years 7.0 7.0 7.0 7.0 7.0 Risk-free interest rate 2.80% 2.94% 2.77% 1.65% 1.84% Expected dividend yield 0.00% 0.00% 0.00% 0.00% 0.00% Loan Agreement Warrants On October 28, 2016, the Company entered into the Loan Agreement as discussed in Note 10. In connection with the Loan Agreement, the Company issued to the Lenders Warrants to purchase a total of 152,580 shares of the Company’s Class A Common Stock at an exercise price of $6.39 per share. Additionally, upon funding of the second tranche on March 24, 2017, the Company issued Warrants to purchase 38,006 shares of its Class A Common Stock at a per share exercise price of $5.92 per share, which aggregate exercise price represents 3.0% of the amount available under the second tranche of the Loan Agreement. The Warrants will expire seven years from their date of issuance.

Redeemable Noncontrolling Inter

Redeemable Noncontrolling Interest	12 Months Ended
	Dec. 31, 2021
Noncontrolling Interest [Abstract]
Redeemable Noncontrolling Interest	Note 13: Redeemable Noncontrolling Interest The Company is subject to the Exchange Agreement with respect to the vTv Units representing the outstanding 25.6% noncontrolling interest in vTv LLC (see Note 1). The Exchange Agreement requires the surrender of an equal number of vTv Units and Class B Common Stock for (i) shares of Class A Common Stock on a one The redeemable noncontrolling interest is recognized at the higher of (1) its initial fair value plus accumulated earnings/losses associated with the noncontrolling interest or (2) the redemption value as of the balance sheet date. At December 31, 2021, and 2020, the redeemable noncontrolling interest was recorded based on the redemption value as of the balance sheet date of $25.0 million and $83.9 million, respectively. Changes in the Company’s ownership interest in vTv LLC while the Company retains its controlling interest in vTv LLC are accounted for as equity transactions, and the Company is required to adjust noncontrolling interest and equity for such changes. The following is a summary of net income attributable to vTv Therapeutics Inc. and transfers to noncontrolling interest: December 31, 2021 2020 2019 Net loss attributable to vTv Therapeutics Inc. common shareholders $ (12,987 ) $ (8,499 ) $ (17,913 ) Increase in vTv Therapeutics Inc. accumulated deficit for purchase of LLC Units as a result of common stock issuances (5,084 ) (8,943 ) (17,971 ) Change from net loss attributable to vTv Therapeutics Inc. common shareholders and transfers to noncontrolling interest $ (18,071 ) $ (17,442 ) $ (35,884 )

Related-Party Transactions

Related-Party Transactions	12 Months Ended
	Dec. 31, 2021
Related Party Transactions [Abstract]
Related-Party Transactions	Note 14: Related-Party Transactions MacAndrews & Forbes Incorporated MacAndrews directly or indirectly controls 23,084,267 shares of Class B Common Stock. Further, as of December 31, 2021, MacAndrews directly or indirectly holds 36,519,212 shares of the Company’s Class A Common Stock. As a result, MacAndrews’ holdings represent approximately 66.2% of the combined voting power of the Company’s outstanding common stock. The Company has entered into several agreements with MacAndrews or its affiliates as further detailed below: F-23 Letter Agreements The Company has entered into the Letter Agreements with MacAndrews. Under the terms of the Letter Agreements, the Company has the right to sell to MacAndrews shares of its Class A Common Stock at a specified price per share , and MacAndrews has the right (exercisable up to three times) to require the Company to sell to it shares of Class A Common Stock at the same price. Certain terms of these Letter Agreements are set forth in the tables below: December 5, 2017 Letter Agreement July 30 11, 2018 Letter Agreement December 11, 2018 Letter Agreement March 18, 2019 Letter Agreement September 26, 2019 Letter Agreement December 23, 2019 Letter Agreement Aggregate dollar value to be sold under agreement $10.0 million $10.0 million $10.0 million $9.0 million $10.0 million $10.0 million Specified purchase price per share $ 4.38 $ 1.33 $ 1.84 $ 1.65 $ 1.46 $ 1.60 Expiration date of letter agreement December 5, 2018 July 30 ,2019 December 11, 2019 March 18, 2020 September 26, 2020 December 23, 2020 Shares available to be issued under related warrants 198,267 518,654 340,534 — 400,990 365,472 Exercise price of related warrants $ 5.04 $ 1.53 $ 2.12 $ — $ 1.68 $ 1.84 Expiration date of related warrants December 5, 2024 July 30, 2025 December 11, 2025 September 26, 2026 December 23, 2026 Total shares issued as of December 31, 2021 2,283,105 7,518,797 5,434,783 5,454,546 6,849,316 6,250,000 Remaining shares to be issued as of December 31, 2021 — — — — Each of the December 5, 2017 and July 30, 2018 Letter Agreements resulted in a deemed capital contribution to the Company as the fair value of the financial instrument received by the Company exceeded the fair value of those financial instruments issued to MacAndrews. The December 11, 2018, March 18, 2019, September 26, 2019, and December 23, 2019 Letter Agreements resulted in a deemed distribution to MacAndrews as the fair value of the financial instruments issued to MacAndrews exceeded the fair value of the financial instrument received by the Company. This deemed distribution has been reflected as a reduction to the net loss attributable to common shareholders of vTv Therapeutics Inc. for computing net loss per share. Exchange Agreement Pursuant to the terms of the Exchange Agreement, but subject to the Amended and Restated LLC Agreement of vTv Therapeutics LLC, the vTv Units (along with a corresponding number of shares of the Class B Common Stock) are exchangeable for (i) shares of the Class A Common Stock on a one Tax Receivable Agreement The Tax Receivable Agreement among the Company, M&F TTP Holdings Two LLC, as successor in interest to vTv Therapeutics Holdings (“M&F”) F-24 Investor Rights Agreement The Company is party to an investor rights agreement with M&F, as successor in interest to vTv Therapeutics Holdings (the “Investor Rights Agreement”). The Investor Rights Agreement provides M&F with certain demand, shelf and piggyback registration rights with respect to its shares of Class A Common Stock and also provides M&F with certain governance rights, depending on the size of its holdings of Class A Common Stock. Under the Investor Rights Agreement, M&F was initially entitled to nominate a majority of the members of the Board of Directors and designate the members of the committees of the Board of Directors.

Employee Benefit Plan

Employee Benefit Plan	12 Months Ended
	Dec. 31, 2021
Compensation And Retirement Disclosure [Abstract]
Employee Benefit Plan	Note 15: Employee Benefit Plan The Company has a 401(k)-retirement plan in which all of its full-time employees are eligible to participate. The plan provides for the Company to make discretionary 50% matching contributions up to a maximum of 6% of employees’ eligible compensation. The Company contributed $0.1 million to the plan for each of the years ended December 31, 2021, 2020, and 2019.

Income Taxes

Income Taxes	12 Months Ended
	Dec. 31, 2021
Income Tax Disclosure [Abstract]
Income Taxes	Note 16: Income Taxes From August 1, 2015, vTv Therapeutics Inc. has been subject to U.S. federal income taxes as well as state taxes. The Company recorded an income tax provision of $0.1 million for the years ended December 31, 2021, and 2019, representing foreign withholding taxes incurred in connection with payments received under license agreements with foreign entities. The Company did not record an income tax provision for the year ended December 31, 2020. As discussed in Note 14, the Company is party to a tax receivable agreement with a related party which provides for the payment by the Company to M&F (or certain of its transferees or other assignees) of 85% of the amount of cash savings, if any, in U.S. federal, state and local income tax or franchise tax that the Company actually realizes (or, in some circumstances, the Company is deemed to realize) as a result of certain transactions. As no transactions have occurred which would trigger a liability under this agreement, the Company has not recognized any liability related to this agreement as of December 31, 2021. In December 2019, the FASB issued ASU 2019-12, which intended to simplify various aspects related to accounting for income taxes. ASU 2019-12 removes certain exceptions to the general principles in ASC 740 and also clarifies and amends existing guidance to improve consistent application of ASC 740. This guidance is effective for fiscal years beginning after December 15, 2020, including interim periods therein, and early adoption is permitted. The adoption of ASU 2019-12 in 2021 did not have a material effect on the Company’s consolidated financial statements. On March 27, 2020, the Coronavirus Aid, Relief and Economic Security Act (“CARES Act”) was enacted in response to COVID-19 pandemic. Under ASC 740, the effects of changes in tax rates and laws are recognized in the period which the new legislation is enacted. The CARES Act made various tax law changes including among other things (i) increased the limitation under IRC Section 163(j) for 2019 and 2020 to permit additional expensing of interest, (ii) enacted a technical correction so that qualified improvement property can be immediately expensed under IRC Section 168(k), (iii) made modifications to the federal net operating loss rules including permitting federal net operating losses incurred in 2018, 2019, and 2020 to be carried back to the five preceding taxable years in order to generate a refund of previously paid income taxes, and (iv) enhanced recoverability of AMT tax credits. Given the Company’s full valuation allowance position, the CARES Act did not have a material impact on the financial statements. A reconciliation of the U.S. statutory income tax rate to the Company’s effective tax rate is as follows (in thousands): December 31, 2021 2020 2019 U.S. statutory tax benefit $ (3,699 ) $ (2,688 ) $ (4,586 ) Partnership income (federal) not subject to tax to the Company 996 904 1,868 Foreign withholding tax 91 — 79 State taxes (net of federal benefit) (14 ) (13 ) 134 Research and development tax credit (173 ) (138 ) (231 ) Other 10 75 (81 ) Change in valuation allowance 2,904 1,860 2,917 Provision for income taxes $ 115 $ — $ 100 Effective income tax rate -0.7 % 0.0 % -0.5 % F-25 Significant components of our net deferred tax assets/(liabilities) are as follows (in thousands): December 31, 2021 2020 Deferred tax assets: Net operating loss carryforwards $ 20,909 $ 17,338 R&D Tax Credit carryforwards 1,755 1,587 Investment in partnerships (2,353 ) (1,520 ) Charitable contributions 11 12 Total deferred tax assets 20,322 17,417 Valuation allowance (20,322 ) (17,417 ) Net deferred tax assets $ — $ — The Company assesses the available positive evidence and negative evidence to estimate whether sufficient future taxable income will be generated to permit use of existing deferred tax assets. A significant piece of objective negative evidence evaluated was the Company’s recent operating losses. Such objective evidence limits the ability to consider other subjective evidence, such as forecasts of profitability. Based on the weight of objective evidence, including cumulative pre-tax losses in recent years, the Company concluded that its deferred tax assets were not realizable on a more-likely-than-not basis and recorded a full valuation allowance. During the year ended December 31, 2021, the Company’s valuation allowance increased by $2.9 million. The Company has federal net operating loss carryforwards of $95.9 million that will be available to offset future taxable income. Approximately, $40.0 million of these carryforwards expire in varying amounts starting in 2035 to 2037, if not utilized and are available to offset 100% of future taxable income. The remaining $55.9 million may be carried forward indefinitely but are only available to offset 80% of future taxable income. The Company has federal research and development tax credits of $1.8 million which expire in varying amounts starting in 2035 to 2040. The Company applies applicable authoritative guidance which prescribes a comprehensive model for the manner in which a company should recognize, measure, present and disclose in its financial statements all material uncertain tax positions that the Company has taken or expects to take on a tax return. As of December 31, 2021, the Company had no uncertain tax positions. There are no uncertain tax positions for which it is reasonably possible that the total amount of unrecognized tax benefits will significantly increase or decrease within twelve months of December 31, 2021. The Company files U.S. federal, New York, North Carolina and Virginia tax returns. The earliest open tax years that are still subject to examination by the IRS and the aforementioned state tax authorities are 2017 to 2021.

Restructuring

Restructuring	12 Months Ended
	Dec. 31, 2021
Restructuring And Related Activities [Abstract]
Restructuring	Note 17: Restructuring In October 2021 the Company entered into a retirement and consulting agreement with its former CEO Stephen Holcombe where he will transition to the role of Strategic Advisor to the CEO until December 31, 2022. As of December 31, 2021, the Company recorded a liability of $0.4 million and $0.2 million in accrued expenses for the cash payments under the retirement and consulting agreement respectively, for Mr. Holcombe. The Company made cash payments under the retirement agreement of $0.1 million during the year ended December 31, 2021, and the remaining payments will be paid over the next twelve months. In addition, the Company recorded $0.5 million and $0.2 million in severance and consulting fees respectively during the year ended December 31, 2021, on the Company’s Consolidated Statements of Operations. In December 2021, the Company announced a strategic decision to prioritize the development of its lead program TTP399

Net Loss per Share

Net Loss per Share	12 Months Ended
	Dec. 31, 2021
Earnings Per Share [Abstract]
Net Loss per Share	Note 18: Net Loss per Share Basic loss per share is computed by dividing net loss attributable to vTv Therapeutics Inc. by the weighted average number of shares of Class A Common Stock outstanding during the period. Diluted loss per share is computed giving effect to all potentially dilutive shares. Diluted loss per share for the years ended December 31, 2021, 2020, and 2019 is the same as basic loss per share as the inclusion of potentially issuable shares would be antidilutive. F-26 A reconciliation of the numerator and denominator used in the calculation of basic and diluted net loss per share of Class A Common Stock is as follows (amounts in thousands, except per share amounts): Year Ended December 31, 2021 2020 2019 Numerator: Net loss $ (17,731 ) $ (12,802 ) $ (21,938 ) Less: Net loss attributable to noncontrolling interests (4,744 ) (4,303 ) (8,894 ) Net loss attributable to vTv Therapeutics Inc. (12,987 ) (8,499 ) (13,044 ) Less: Deemed distribution to related party (Note 13) — — (4,869 ) Net loss attributable to common shareholders of vTv Therapeutics Inc., basic and diluted $ (12,987 ) $ (8,499 ) $ (17,913 ) Denominator: Weighted average vTv Therapeutics Inc. Class A Common Stock, basic and diluted 60,732,636 47,137,917 30,292,030 Net loss per share of vTv Therapeutics Inc. Class A Common Stock, basic and diluted $ (0.21 ) $ (0.18 ) $ (0.59 ) Potentially dilutive securities not included in the calculation of dilutive net loss per share are as follows: Year Ended December 31, 2021 2020 2019 Class B Common Stock (1) 23,093,860 23,094,221 23,094,221 Common stock options granted under the Plan 7,056,035 4,453,357 2,531,143 Restricted stock units — — 11,667 Common stock options granted under the Letter Agreement — — 6,250,000 Common stock warrants 2,014,503 2,014,503 2,014,503 Total 32,164,398 29,562,081 33,901,534 (1) Shares of Class B Common Stock do not share in the Company’s earnings and are not participating securities. Accordingly, separate presentation of loss per share of Class B Common Stock under the two-class method has not been provided. Each share of Class B Common Stock (together with a corresponding vTv Unit) is exchangeable for one share of Class A Common Stock.

Fair Value of Financial Instrum

Fair Value of Financial Instruments	12 Months Ended
	Dec. 31, 2021
Fair Value Disclosures [Abstract]
Fair Value of Financial Instruments	Note 19: Fair Value of Financial Instruments The carrying amount of certain of the Company’s financial instruments, including cash and cash equivalents, net accounts receivable, accounts payable and other accrued liabilities approximate fair value due to their short-term nature. The Company measures the value of its equity investments without readily determinable fair values at cost minus impairment, if any, plus or minus changes resulting from observable price changes in orderly transactions for the identical or similar investment. During the year ended December 31, 2021, Reneo completed its initial public offering. As a result, the fair value of the Company’s investment in Reneo’s common stock now has a readily determinable market value and is no longer eligible for the practical expedient for investments without readily determinable fair market values. F-27 Assets and Liabilities Measured at Fair Value on a Recurring Basis The Company evaluates its financial assets and liabilities subject to fair value measurements on a recurring basis to determine the appropriate level in which to classify them for each reporting period. This determination requires significant judgments. The following table summarizes the conclusions reached regarding fair value measurements as of December 31, 2021, 2020 and 2019 (in thousands): Balance at December 31, 2021 Quoted Prices in Active Markets for Identical Assets (Level 1) Significant Other Observable Inputs (Level 2) Significant Unobservable Inputs (Level 3) Assets: Equity securities with readily determinable fair value $ 4,928 $ 4,928 $ — $ — Total $ 4,928 $ 4,928 $ — $ — Liabilities: Warrant liability, related party (1) $ 1,262 $ — $ — $ 1,262 Total $ 1,262 $ — $ — $ 1,262 Balance at December 31, 2020 Quoted Prices in Active Markets for Identical Assets (Level 1) Significant Other Observable Inputs (Level 2) Significant Unobservable Inputs (Level 3) Warrant liability, related party (1) $ 2,871 $ — $ — $ 2,871 Total $ 2,871 $ — $ — $ 2,871 (1) Fair value determined using the Black-Scholes option pricing model. Expected volatility is based on a portfolio of selected stocks of companies believed to have market and economic characteristics similar to its own. The risk-free rate is based on the U.S. Treasury yield curve in effect at the time of valuation. Changes in Level 3 Instruments for the years ended December 31, 2021, 2020 and 2019 Balance at January 1 Net Change in fair value included in earnings Purchases / Issuance Sales / Repurchases Balance at December 31, 2021 Warrant liability, related party $ 2,871 $ (1,609 ) $ — $ — $ 1,262 Total $ 2,871 $ (1,609 ) $ — $ — $ 1,262 2020 Warrant liability, related party 2,601 270 — — 2,871 Total $ 2,601 $ 270 $ — $ — $ 2,871 2019 Warrant liability, related party 2,436 (827 ) 992 — 2,601 Total $ 2,436 $ (827 ) $ 992 $ — $ 2,601 There were no transfers into or out of level 3 instruments and/or between level 1 and level 2 instruments during the years ended December 31, 2021, 2020 and 2019. Gains and losses recognized due to the change in fair value of the warrant liability, related party are recognized as a component of other (expense) income, related party in the Consolidated Statements of Operations The fair value of the Letter Agreement Warrants was determined using the Black-Scholes option pricing model or option pricing models based on the Company’s current capitalization. Expected volatility is based on a portfolio of selected stocks of companies F-28 believed to have market and economic characteristics similar to its own. The risk-free rate is based on the U.S. Treasury yield curve in effect at the time of valuation. S ignificant inputs utilized in the valuation of the Letter Agreement Warrants were: December 31, 2021 December 31, 2020 Range Weighted Average Range Weighted Average Expected volatility 82.68% - 142.86% 128.13% 120.53% - 142.07% 128.16% Risk-free interest rate 0.95% - 1.26% 1.15% 0.26% - 0.50% 0.39% The weighted average expected volatility and risk-free interest rate was based on the relative fair values of the warrants. Changes in the unobservable inputs noted above would impact the amount of the liability for the Letter Agreement Warrants. For the Company’s warrants, increases (decreases) in the estimates of the Company’s annual volatility would increase (decrease) the liability and an increase (decrease) in the annual risk-free rate would increase (decrease) the liability.

Subsequent Events

Subsequent Events	12 Months Ended
	Dec. 31, 2021
Subsequent Events [Abstract]
Subsequent Events	Note 20: Subsequent Events On February 27, 2022, Ms. Deepa Prasad notified the Board of Directors (the “Board”) of vTv Therapeutics Inc. (the “Company”) of her decision to resign from her positions as Chief Executive Officer, President and Board member, effective as of March 29, 2022, and has agreed to continue serving in those roles until the earlier of the completion of a certain Company milestone or March 29, 2022 (the “Effective Date”). Ms. Prasad has agreed to serve as a Strategic Advisor to the Company for six months after the Effective Date. Ms. Prasad will retain 624,659 of the outstanding options previously granted to her, which will vest at the end of the 15-month period following the Effective Date. Ms. Prasad will be subject to a one-year noncompete provision and other customary provisions, including mutual non-disparagement obligations and the execution of a mutual release. On March 1, 2022, the Board appointed Mr. Richard S. Nelson, a member of the Company’s Board of Directors, as Acting Chief Executive Officer until the Effective Date, at which time Mr. Nelson will become Interim Chief Executive Officer of the Company On March 1, 2022, Mr. Nelson entered into an employment agreement with the Company (the “Nelson Employment Agreement”). The Nelson Employment Agreement provides for a base salary of not less than $200,000, and a cash bonus of 100% of his base salary for the 2022 fiscal year, based on achievement of performance targets. The Nelson Employment Agreement also provides for the grant of stock options (the “Options”) to purchase 500,000 shares of Class A common stock of the Company at an exercise price of $0.8060 per share. One hundred and twenty-five thousand (125,000) of the Options will vest on the Effective Date, and the remaining 375,000 Options will vest ratably every three months over three years, subject to Mr. Nelson’s continued association with the Company.

Summary of Significant Accoun_2

Summary of Significant Accounting Policies (Policies)	12 Months Ended
	Dec. 31, 2021
Accounting Policies [Abstract]
Use of Estimates	Use of Estimates The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires the Company to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities as of the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. On an ongoing basis, the Company evaluates its estimates, including those related to the grant date fair value of equity awards, the fair value of warrants to purchase shares of its Class A Common Stock, the fair value of its Class B Common Stock, the useful lives of property and equipment and the fair value of the Company’s debt, among others. The Company bases its estimates on historical experience and on various other assumptions that it believes to be reasonable, the results of which form the basis for making judgments about the carrying value of assets and liabilities.
Concentration of Credit Risk	Concentration of Credit Risk Financial instruments that potentially expose the Company to concentrations of credit risk consist principally of cash on deposit with multiple financial institutions. The balances of these cash accounts frequently exceed insured limits. Three customers represented 100% of the revenue earned during the year ended December 31, 2021, and 2020. Four customers represented 100% of the revenue earned during the year ended December 31, 2019.
Cash and Cash Equivalents	Cash and Cash Equivalents The Company considers any highly liquid investments with an original maturity of three months or less to be cash and cash equivalents.
Collaboration Revenue and Accounts Receivable	Collaboration Revenue and Accounts Receivable The majority of the Company’s collaboration revenue and accounts receivable relates to its agreements to license certain of its potential drug products for development. See Note 3 for further discussion of the Company’s collaboration agreements. Accounts receivable are stated at net realizable value. On a periodic basis, the Company evaluates its accounts receivable and establishes an allowance based on its history of collections and write-offs and the current status of all receivables.
Property and Equipment and other Long-lived Assets	Property and Equipment and other Long-lived Assets The Company records property and equipment at cost less accumulated depreciation. Costs of renewals and improvements that extend the useful lives of the assets are capitalized. Maintenance and repairs are expensed as incurred. Depreciation is determined on a straight-line basis over the estimated useful lives of the assets, which generally range from three to ten years. Leasehold improvements are depreciated over the shorter of the useful life of the asset or the term of the related lease. Upon retirement or disposition of assets, the costs and related accumulated depreciation are removed from the accounts with the resulting gains or losses, if any, reflected in results of operations. F-9 The estimated useful lives of property and equipment are as follows: Asset Category Useful Life (in years) Laboratory equipment 7 Computers and hardware 3-5 Furniture and office equipment 3-7 Software 3 Leasehold improvements Shorter of useful life or remaining term of lease The Company periodically assesses it property and equipment and other long-lived assets for impairment in accordance with the relevant accounting guidance. No such charges were recognized during the years ended December 31, 2021, 2020 or 2019. There were no assets held for sale at December 31, 2021, or 2020.
Investments	Investments Investments in entities in which the Company has no control or significant influence, is not the primary beneficiary, and have a readily determinable fair value are classified as equity investments with readily determinable fair value. The investments are measured at fair value based on a quoted market price per unit in active markets multiplied by the number of units held without consideration of transaction costs (Level 1). Gains and losses are recorded in other income (expense), net on the Consolidated Statements of Operations. Equity investments without readily determinable fair value include ownership rights that do not provide the Company with control or significant influence and these investments do not have readily determinable fair values. The Company has elected to measure its equity investments without readily determinable fair values at cost minus impairment, if any, plus or minus changes resulting from observable price changes in orderly transactions for the identical or similar investment .
Revenue Recognition	Revenue Recognition The Company uses the revenue recognition guidance established by ASC Topic 606, “Revenue From Contracts With Customers” (“ASC Topic 606”). The majority of the Company’s revenue results from its license and collaboration agreements associated with the development of investigational drug products. The Company accounts for a contract when it has approval and commitment from both parties, the rights of the parties are identified, payment terms are identified, the contract has commercial substance and collectability of consideration is probable. The transaction price under the contract is determined based on the value of the consideration expected to be received in exchange for the transferred assets or services. Development, regulatory and sales milestones included in the Company’s collaboration agreements are considered to be variable consideration. The amount of variable consideration expected to be received is included in the transaction price when it becomes probable that the milestone will be met. For contracts with multiple performance obligations, the contract’s transaction price is allocated to each performance obligation using the Company’s best estimate of the standalone selling price of each distinct good or service in the contract. The primary method used to estimate standalone selling price is the expected cost plus margin approach. Revenue is recognized over the related period over which the Company expects the services to be provided using a proportional performance model or a straight-line method of recognition if there is no discernable pattern over which the services will be provided.
Fair Value of Financial Instruments	Fair Value of Financial Instruments The Company uses a three-tier fair value hierarchy to classify and disclose all assets and liabilities measured at fair value on a recurring basis, as well as assets and liabilities measured at fair value on a non-recurring basis, in periods subsequent to their initial measurement. The hierarchy requires the Company to use observable inputs when available, and to minimize the use of unobservable inputs, when determining fair value. The three tiers are defined as follows: • Level 1—Observable inputs that reflect quoted market prices (unadjusted) for identical assets or liabilities in active markets; • Level 2—Observable inputs other than quoted prices in active markets that are observable either directly or indirectly in the marketplace for identical or similar assets and liabilities; and • Level 3—Unobservable inputs that are supported by little or no market data, which require the Company to develop its own assumptions.
Research and Development	Research and Development Major components of research and development costs include cash compensation, depreciation expense on research and development property and equipment, costs of preclinical studies, clinical trials and related clinical manufacturing, costs of drug development, costs of materials and supplies, facilities cost, overhead costs, regulatory and compliance costs, and fees paid to consultants and other entities that conduct certain research and development activities on the Company’s behalf. Research and development costs are expensed as incurred. The Company records accruals based on estimates of the services received, efforts expended and amounts owed pursuant to contracts with numerous contract research and manufacturing organizations. In the normal course of business, the Company contracts with third parties to perform various clinical study activities in the ongoing development of potential products. The financial terms of these agreements are subject to negotiation and variation from contract to contract and may result in uneven payment flows. Payments under the contracts depend on factors such as the achievement of certain events and the completion of portions of the clinical study or similar conditions. The objective of the Company’s accrual policy is to match the recording of expenses in its financial statements to the actual services received and efforts expended. As such, expense accruals related to clinical studies are recognized based on the Company’s estimate of the degree of completion of the event or events specified in the specific clinical study. The Company records nonrefundable advance payments it makes for future research and development activities as prepaid expenses. Prepaid expenses are recognized as expense in the Consolidated Statements of Operations as the Company receives the related goods or services. Research and development costs that are reimbursed under a cost-sharing arrangement are reflected as a reduction of research and development expense.
Patent Costs	Patent Costs Patent costs, including related legal costs, are expensed as incurred and recorded within general and administrative operating expenses on the Consolidated Statements of Operations.
Income Taxes	Income Taxes From its formation on August 1, 2015, vTv Therapeutics Inc. has been subject to corporate level income taxes. Prior to July 30, 2015, the Company’s predecessor entities were taxed as partnerships and all their income and deductions flowed through and were subject to tax at the partner level. vTv Therapeutics Inc. is required to recognize deferred tax assets and liabilities for the difference between the financial reporting and tax basis of its investment in vTv LLC. The Company’s income tax expense, deferred tax assets and liabilities and reserves for unrecognized tax benefits reflect management’s best assessment of estimated future taxes to be paid. The Company is subject to income taxes in both the United States and various state jurisdictions. Significant judgments and estimates are required in determining the consolidated income tax expense. The Company accounts for income taxes under the asset and liability method, which requires the recognition of deferred tax assets and liabilities for the expected future tax consequences of events included in the financial statements. Under this method, the Company determines deferred tax assets and liabilities on the basis of differences between the financial statement and tax bases of assets and liabilities by using enacted tax rates in effect for the year in which the differences are expected to reverse. The effect of a change in tax rates on deferred tax assets and liabilities is recognized in income in the period in which the enactment date occurs. F-11 The Company recognizes deferred tax assets to the extent it believes these assets are more-likely-than-not to be realized. In making such a determination, the Company considers all available positive and negative evidence, including future reversals of existing taxable temporary differences, projected future taxable income, tax planning strategies and recent results of operations. The Company records uncertain tax positions on the basis of a two-step process in which (1) it determines whether it is more-likely-than-not that the tax positions will be sustained on the basis of the technical merits of the position and (2) for those tax positions meeting the more-likely-than-not recognition threshold, it recognizes the largest amount of tax benefit that is more than 50% likely to be realized upon ultimate settlement with the related tax authority. Interest and penalties related to income taxes are included in the benefit (provision) for income taxes in the Company’s Consolidated Statements of Operations. The Company has not incurred any significant interest or penalties related to income taxes in any of the periods presented.
Noncontrolling Interest	Noncontrolling Interest The Company records the redeemable noncontrolling interest represented by the vTv Units and the Class B Common stock at the higher of (1) its initial fair value plus accumulated earnings/losses associated with the noncontrolling interest or (2) the redemption value as of the balance sheet date. See discussion and additional detail of the redeemable noncontrolling interest at Note 13.
Segment and Geographic Information	Segment and Geographic Information Operating segments are defined as an enterprise’s components (business activities from which it earns revenue and incurs expenses) for which discrete financial information is (1) available; and (2) is regularly reviewed by the chief operating decision maker (“CODM”) in deciding how to allocate resources and in assessing performance. The Company’s CODM is its President and Chief Executive Officer. The Company’s business operates in one reportable segment comprised of one operating segment.
Leases	Leases The Company determines if an arrangement is a lease at inception. Balances recognized related to operating leases are included in operating lease right-of-use assets and operating lease liabilities in the Consolidated Balance Sheets. Operating lease right-of-use assets and operating lease liabilities are recognized based on the present value of the future minimum lease payments over the lease term at commencement date. Lease terms may include options to extend of terminate the lease if it is reasonably certain that the Company will exercise the option. As most of the Company’s leases do not provide an implicit rate, the Company uses its incremental borrowing rate based on the information available at the commencement date in determining the present value of future payments. The operating lease right-of-use asset also includes any lease payments made and excludes lease incentives and initial direct costs incurred. The Company has elected a practical expedient to not separate its lease and non-lease components and instead account for them as a single lease component. Lease expense for minimum lease payments is recognized on a straight-line basis over the lease term. Lease payments for short-term leases are recorded to operating expense on a straight-line basis and variable lease payments are recorded in the period in which the obligation for those payments is incurred.
Share-Based Compensation	Share-Based Compensation Compensation expense for share-based compensation awards issued is based on the fair value of the award at the date of grant, and compensation expense is recognized for those awards earned over the service period. The grant date fair value of stock option awards is estimated using the Black-Scholes option pricing formula. Expected volatility is based on the historical volatility of the Company’s common stock over the most recent period commensurate with the estimated expected term of the Company’s stock options offering period which is derived from historical experience. In the event the participant’s employment by or engagement with (as a director or otherwise) the Company terminates before exercise of the options granted, the stock options granted to the participant shall immediately expire and all rights to purchase shares there under shall immediately cease and expire and be of no further force or effect, other than applicable exercise rights for vested shares that may extend past the termination date as provided for in the participant’s applicable option award agreement. The Company entered into a retirement agreement with its former CEO Steve Holcombe in October 2021, and separation agreements with certain key employees in December 2021. The retirement and separation agreements provide for accelerated vesting and extend the exercise period for certain outstanding equity awards. F-12 The fair value of restricted stock units (“RSU”) grants are based on the market value of the Class A Common Stock on the date of grant. The Company also estimates the amount of share-based awards that are expected to be forfeited based on historical employee turnover rates.
Comprehensive Income	Comprehensive Income The Company does not have any components of other comprehensive income recorded within its Consolidated Financial Statements, and, therefore, does not separately present a statement of comprehensive income in its Consolidated Financial Statements.
Recently Issued Accounting Pronouncements	Recently Issued Accounting Pronouncements There have been no recently issued accounting pronouncements which are expected to have a material impact on the Company’s financial statements.

Summary of Significant Accoun_3

Summary of Significant Accounting Policies (Tables)	12 Months Ended
	Dec. 31, 2021
Accounting Policies [Abstract]
Summary of Estimated Useful Lives of Property and Equipment	The estimated useful lives of property and equipment are as follows: Asset Category Useful Life (in years) Laboratory equipment 7 Computers and hardware 3-5 Furniture and office equipment 3-7 Software 3 Leasehold improvements Shorter of useful life or remaining term of lease

Collaboration Agreements (Table

Collaboration Agreements (Tables)	12 Months Ended
	Dec. 31, 2021
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Summary of Contract Liabilities Related to Company's Collaboration Agreements	Contract liabilities related to the Company’s collaboration agreements consisted of the following (in thousands): December 31, 2021 December 31, 2020 Current portion of contract liabilities $ 35 $ 31 Contract liabilities, net of current portion — 1,009 Total contract liabilities $ 35 $ 1,040 F-15

Share-Based Compensation (Table

Share-Based Compensation (Tables)	12 Months Ended
	Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Assumptions Used to Estimate Fair Value of Stock Option Awards Granted	The Company uses the Black-Scholes option pricing model to calculate the fair value of stock options granted. The fair value of stock options granted was estimated using the following assumptions during the years ended December 31, 2021, 2020 and 2019: For the Year Ended December 31, 2021 2020 2019 Expected volatility 118.75% - 122.17% 120.37% - 121.43% 115.29% - 120.15% Expected life of option, in years 5.8 - 6.0 5.7 - 6.0 5.3 - 6.0 Risk-free interest rate 1.00% - 1.34% 0.39% - 0.53% 1.58% - 2.64% Expected dividend yield 0.00% 0.00% 0.00%
Summary of Stock Award Activity for the Period	The following table summarizes the activity related to the stock option awards for the year ended December 31, 2021 (in thousands, except per share amounts): Number of Shares Weighted Average Exercise Price Awards outstanding at December 31, 2020 4,453,357 $ 4.41 Granted 3,368,635 1.43 Exercised (20,833 ) 2.24 Forfeited (745,124 ) 2.60 Awards outstanding at December 31, 2021 7,056,035 $ 3.19 Options exercisable at December 31, 2021 2,908,180 $ 5.50 Weighted average remaining contractual term 6.3 Years Options vested and expected to vest at December 31, 2021 5,960,235 $ 3.50 Weighted average remaining contractual term 7.9 Years
Summary of Compensation Expense Related to Grants of Stock Options	Compensation expense related to the grants of stock options is included in research and development and general and administrative expense as follows (in thousands): 2021 2020 2019 Research and development $ 599 $ 348 $ 522 General and administrative 1,757 661 996 Total share-based compensation expense $ 2,356 $ 1,009 $ 1,518

Prepaid Expenses and Other Cu_2

Prepaid Expenses and Other Current Assets (Tables)	12 Months Ended
	Dec. 31, 2021
Prepaid Expense And Other Assets Current [Abstract]
Summary of Prepaid Expenses and Other Current Assets	Prepaid expenses and other current assets consist of the following (in thousands): December 31, 2021 2020 Prepaid insurance $ 863 $ 771 Prepaid taxes 97 129 Deferred financing costs 135 — Prepaid - other 954 39 Total $ 2,049 $ 939

Property and Equipment (Tables)

Property and Equipment (Tables)	12 Months Ended
	Dec. 31, 2021
Property Plant And Equipment [Abstract]
Summary of Property and Equipment	Property and equipment consists of the following (in thousands): December 31, 2021 2020 Leasehold improvements $ 406 $ 406 Computers and hardware 48 48 Software 80 80 Furniture and office equipment 49 49 Total property and equipment 583 583 Less: accumulated depreciation and amortization (305 ) (216 ) Property and equipment, net $ 278 $ 367

Investments (Tables)

Investments (Tables)	12 Months Ended
	Dec. 31, 2021
Investments Debt And Equity Securities [Abstract]
Schedule of Equity Investments with and without Readily Determinable Fair Values Assessed	T he Company’s investments consist of the following: December 31, 2021 December 31, 2020 Equity investment with readily determinable fair value: Reneo common stock $ 4,928 $ — Equity investment without readily determinable fair values assessed under the measurement alternative: Reneo common stock — 2,480 Anteris preferred stock 4,245 4,245 Total $ 9,173 $ 6,725

Accounts Payable and Accrued _2

Accounts Payable and Accrued Expenses (Tables)	12 Months Ended
	Dec. 31, 2021
Payables And Accruals [Abstract]
Schedule of Accounts Payable and Accrued Liabilities	Accounts payable and accrued expenses consist of the following (in thousands): December 31, 2021 2020 Accounts payable $ 1,876 $ 1,925 Accrued development costs 2,790 2,581 Accrued compensation and related costs 3,202 1,594 Accrued other 155 20 Total $ 8,023 $ 6,120

Leases (Tables)

Leases (Tables)	12 Months Ended
	Dec. 31, 2021
Leases [Abstract]
Schedule of Maturities of Lease Liabilities for Operating Leases	Maturities of lease liabilities for the Company’s operating leases as of December 31, 2021, were as follows (in thousands): 2022 $ 261 2023 268 2024 275 2025 23 2026 — Thereafter — Total lease payments 827 Less: imputed interest (151 ) Present value of lease liabilities $ 676

Notes Payable (Tables)

Notes Payable (Tables)	12 Months Ended
	Dec. 31, 2021
Debt Disclosure [Abstract]
Schedule of Notes Payable	Notes payable consist of the following (in thousands): December 31, 2021 December 31, 2020 Notes payable under the Loan Agreement $ — $ — Short-term financing 256 84 Total notes payable 256 84 Less: Current portion (256 ) (84 ) Total notes payable, net of current portion $ — $ —

Stockholders' Equity (Tables)

Stockholders' Equity (Tables)	12 Months Ended
	Dec. 31, 2021
Assumptions Used to Calculate Fair Value of Warrants	S ignificant inputs utilized in the valuation of the Letter Agreement Warrants were: December 31, 2021 December 31, 2020 Range Weighted Average Range Weighted Average Expected volatility 82.68% - 142.86% 128.13% 120.53% - 142.07% 128.16% Risk-free interest rate 0.95% - 1.26% 1.15% 0.26% - 0.50% 0.39%
Warrant Liability [Member]
Assumptions Used to Calculate Fair Value of Warrants	Fair value of the Letter Agreement Warrants was calculated as of their issuance date using the methods described in Note 19 using the following assumptions: December 5, 2017 July 30, 2018 December 11, 2018 September 26, 2019 December 23, 2019 Expected volatility 90.00% 95.29% 104.46% 110.35% 110.41% Expected life of option, in years 7.0 7.0 7.0 7.0 7.0 Risk-free interest rate 2.80% 2.94% 2.77% 1.65% 1.84% Expected dividend yield 0.00% 0.00% 0.00% 0.00% 0.00%

Redeemable Noncontrolling Int_2

Redeemable Noncontrolling Interest (Tables)	12 Months Ended
	Dec. 31, 2021
Noncontrolling Interest [Abstract]
Summary of Net Income Attributable to Vtv Therapeutics Inc	The following is a summary of net income attributable to vTv Therapeutics Inc. and transfers to noncontrolling interest: December 31, 2021 2020 2019 Net loss attributable to vTv Therapeutics Inc. common shareholders $ (12,987 ) $ (8,499 ) $ (17,913 ) Increase in vTv Therapeutics Inc. accumulated deficit for purchase of LLC Units as a result of common stock issuances (5,084 ) (8,943 ) (17,971 ) Change from net loss attributable to vTv Therapeutics Inc. common shareholders and transfers to noncontrolling interest $ (18,071 ) $ (17,442 ) $ (35,884 )

Related-Party Transactions (Tab

Related-Party Transactions (Tables)	12 Months Ended
	Dec. 31, 2021
Related Party Transactions [Abstract]
Summary of Terms of Letter Agreements	Certain terms of these Letter Agreements are set forth in the tables below: December 5, 2017 Letter Agreement July 30 11, 2018 Letter Agreement December 11, 2018 Letter Agreement March 18, 2019 Letter Agreement September 26, 2019 Letter Agreement December 23, 2019 Letter Agreement Aggregate dollar value to be sold under agreement $10.0 million $10.0 million $10.0 million $9.0 million $10.0 million $10.0 million Specified purchase price per share $ 4.38 $ 1.33 $ 1.84 $ 1.65 $ 1.46 $ 1.60 Expiration date of letter agreement December 5, 2018 July 30 ,2019 December 11, 2019 March 18, 2020 September 26, 2020 December 23, 2020 Shares available to be issued under related warrants 198,267 518,654 340,534 — 400,990 365,472 Exercise price of related warrants $ 5.04 $ 1.53 $ 2.12 $ — $ 1.68 $ 1.84 Expiration date of related warrants December 5, 2024 July 30, 2025 December 11, 2025 September 26, 2026 December 23, 2026 Total shares issued as of December 31, 2021 2,283,105 7,518,797 5,434,783 5,454,546 6,849,316 6,250,000 Remaining shares to be issued as of December 31, 2021 — — — —

Income Taxes (Tables)

Income Taxes (Tables)	12 Months Ended
	Dec. 31, 2021
Income Tax Disclosure [Abstract]
Schedule of Effective Income Tax Rate Reconciliation	A reconciliation of the U.S. statutory income tax rate to the Company’s effective tax rate is as follows (in thousands): December 31, 2021 2020 2019 U.S. statutory tax benefit $ (3,699 ) $ (2,688 ) $ (4,586 ) Partnership income (federal) not subject to tax to the Company 996 904 1,868 Foreign withholding tax 91 — 79 State taxes (net of federal benefit) (14 ) (13 ) 134 Research and development tax credit (173 ) (138 ) (231 ) Other 10 75 (81 ) Change in valuation allowance 2,904 1,860 2,917 Provision for income taxes $ 115 $ — $ 100 Effective income tax rate -0.7 % 0.0 % -0.5 %
Schedule of Net Deferred Tax Assets/(Liabilities)	Significant components of our net deferred tax assets/(liabilities) are as follows (in thousands): December 31, 2021 2020 Deferred tax assets: Net operating loss carryforwards $ 20,909 $ 17,338 R&D Tax Credit carryforwards 1,755 1,587 Investment in partnerships (2,353 ) (1,520 ) Charitable contributions 11 12 Total deferred tax assets 20,322 17,417 Valuation allowance (20,322 ) (17,417 ) Net deferred tax assets $ — $ —

Net Loss per Share (Tables)

Net Loss per Share (Tables)	12 Months Ended
	Dec. 31, 2021
Earnings Per Share [Abstract]
Reconciliation of the Numerator and Denominator Used in the Calculation of Basic and Diluted Net Loss per Share of Class A Common Stock	F-26 A reconciliation of the numerator and denominator used in the calculation of basic and diluted net loss per share of Class A Common Stock is as follows (amounts in thousands, except per share amounts): Year Ended December 31, 2021 2020 2019 Numerator: Net loss $ (17,731 ) $ (12,802 ) $ (21,938 ) Less: Net loss attributable to noncontrolling interests (4,744 ) (4,303 ) (8,894 ) Net loss attributable to vTv Therapeutics Inc. (12,987 ) (8,499 ) (13,044 ) Less: Deemed distribution to related party (Note 13) — — (4,869 ) Net loss attributable to common shareholders of vTv Therapeutics Inc., basic and diluted $ (12,987 ) $ (8,499 ) $ (17,913 ) Denominator: Weighted average vTv Therapeutics Inc. Class A Common Stock, basic and diluted 60,732,636 47,137,917 30,292,030 Net loss per share of vTv Therapeutics Inc. Class A Common Stock, basic and diluted $ (0.21 ) $ (0.18 ) $ (0.59 )
Schedule of Potentially Dilutive Securities not Included in Calculation of Dilutive Net Loss per Share	Potentially dilutive securities not included in the calculation of dilutive net loss per share are as follows: Year Ended December 31, 2021 2020 2019 Class B Common Stock (1) 23,093,860 23,094,221 23,094,221 Common stock options granted under the Plan 7,056,035 4,453,357 2,531,143 Restricted stock units — — 11,667 Common stock options granted under the Letter Agreement — — 6,250,000 Common stock warrants 2,014,503 2,014,503 2,014,503 Total 32,164,398 29,562,081 33,901,534 (1) Shares of Class B Common Stock do not share in the Company’s earnings and are not participating securities. Accordingly, separate presentation of loss per share of Class B Common Stock under the two-class method has not been provided. Each share of Class B Common Stock (together with a corresponding vTv Unit) is exchangeable for one share of Class A Common Stock.

Fair Value of Financial Instr_2

Fair Value of Financial Instruments (Tables)	12 Months Ended
	Dec. 31, 2021
Fair Value Disclosures [Abstract]
Summarizes the Conclusions Reached Regarding Fair Value Measurements	The following table summarizes the conclusions reached regarding fair value measurements as of December 31, 2021, 2020 and 2019 (in thousands): Balance at December 31, 2021 Quoted Prices in Active Markets for Identical Assets (Level 1) Significant Other Observable Inputs (Level 2) Significant Unobservable Inputs (Level 3) Assets: Equity securities with readily determinable fair value $ 4,928 $ 4,928 $ — $ — Total $ 4,928 $ 4,928 $ — $ — Liabilities: Warrant liability, related party (1) $ 1,262 $ — $ — $ 1,262 Total $ 1,262 $ — $ — $ 1,262 Balance at December 31, 2020 Quoted Prices in Active Markets for Identical Assets (Level 1) Significant Other Observable Inputs (Level 2) Significant Unobservable Inputs (Level 3) Warrant liability, related party (1) $ 2,871 $ — $ — $ 2,871 Total $ 2,871 $ — $ — $ 2,871 (1) Fair value determined using the Black-Scholes option pricing model. Expected volatility is based on a portfolio of selected stocks of companies believed to have market and economic characteristics similar to its own. The risk-free rate is based on the U.S. Treasury yield curve in effect at the time of valuation. Changes in Level 3 Instruments for the years ended December 31, 2021, 2020 and 2019 Balance at January 1 Net Change in fair value included in earnings Purchases / Issuance Sales / Repurchases Balance at December 31, 2021 Warrant liability, related party $ 2,871 $ (1,609 ) $ — $ — $ 1,262 Total $ 2,871 $ (1,609 ) $ — $ — $ 1,262 2020 Warrant liability, related party 2,601 270 — — 2,871 Total $ 2,601 $ 270 $ — $ — $ 2,871 2019 Warrant liability, related party 2,436 (827 ) 992 — 2,601 Total $ 2,436 $ (827 ) $ 992 $ — $ 2,601
Assumptions Used to Calculate Fair Value of Warrants	S ignificant inputs utilized in the valuation of the Letter Agreement Warrants were: December 31, 2021 December 31, 2020 Range Weighted Average Range Weighted Average Expected volatility 82.68% - 142.86% 128.13% 120.53% - 142.07% 128.16% Risk-free interest rate 0.95% - 1.26% 1.15% 0.26% - 0.50% 0.39%

Description of Business and B_2

Description of Business and Basis of Presentation - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Jul. 29, 2015
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Accumulated deficit	$ (248,834)	$ (290,036)
Cash and cash equivalents	$ 13,415	$ 5,747
Class B Common Stock [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Common stock par value	$ 0.01	$ 0.01	$ 0.01
Class A Common Stock [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Common stock par value	$ 0.01	$ 0.01	$ 0.01
Class A Common Stock [Member] | LPC Purchase Agreement [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	9,437,376
Class A Common Stock [Member] | Cantor Fitzgerald [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Remaining available stock value	$ 37,300
vTv Therapeutics LLC [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Percentage of non-voting economic interest of vTv Therapeutics Holdings LLC in vTv LLC	25.60%
Percentage of non-voting economic interest of vTv Therapeutics Inc in vTv LLC	74.40%
vTv Therapeutics LLC [Member] | Class B Common Stock [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Common stock par value	$ 0.01

Summary of Significant Accoun_4

Summary of Significant Accounting Policies - Additional Information (Detail)	12 Months Ended
	Dec. 31, 2021USD ($)CustomerSegment	Dec. 31, 2020USD ($)Customer	Dec. 31, 2019USD ($)Customer
Summary Of Significant Accounting Policies [Line Items]
Assets held for sale	$ 0	$ 0
Asset impairment charges	0	$ 0	$ 0
Significant interest or penalties incurred related to income taxes	$ 0
Number of reportable segment | Segment	1
Number of operating segments | Segment	1
Minimum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	3 years
Maximum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	10 years
Revenue [Member]
Summary Of Significant Accounting Policies [Line Items]
Number of customers | Customer	3	3	4
Revenue [Member] | Customer [Member]
Summary Of Significant Accounting Policies [Line Items]
Concentration risk percentage	100.00%	100.00%	100.00%

Summary of Significant Accoun_5

Summary of Significant Accounting Policies - Summary of Estimated Useful Lives of Property and Equipment (Detail)	12 Months Ended
	Dec. 31, 2021
Minimum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	3 years
Maximum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	10 years
Laboratory Equipment [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	7 years
Computers and Hardware [Member] | Minimum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	3 years
Computers and Hardware [Member] | Maximum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	5 years
Furniture and Office Equipment [Member] | Minimum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	3 years
Furniture and Office Equipment [Member] | Maximum [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	7 years
Software [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	3 years
Leasehold Improvements [Member]
Summary Of Significant Accounting Policies [Line Items]
Property and equipment, estimated useful lives	Shorter of useful life or remaining term of lease

Collaboration Agreements - Addi

Collaboration Agreements - Additional Information (Detail) - USD ($)	Dec. 21, 2017	May 31, 2018	Aug. 31, 2017	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Jan. 14, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development				$ 13,324,000	$ 11,015,000	$ 15,119,000
Collaborative Arrangements [Member] | Reneo [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fee received	$ 3,000,000
Collaboration revenue recognized				2,000,000		1,700,000
Collaborative Arrangements [Member] | Reneo [Member] | Maximum [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential development and regulatory milestone payments	94,500,000
Collaborative Arrangements [Member] | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fee received	8,000,000
Potential regulatory milestone payments based on regulatory approval	20,000,000
Potential sales-based milestones based on tiered sales of licensed products	50,000,000
Collaborative Arrangements [Member] | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. [Member] | Phase 2 MRCT [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential development and regulatory milestone payments							$ 3,000,000
Maximum contribution amount to clinical trial							$ 3,000,000
Unrecognized amount of transaction price allocated to performance obligation				1,000,000
Collaborative Arrangements [Member] | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. [Member] | Phase 2 MRCT [Member] | License and Technology Transfer Services of Chemistry and Manufacturing Know-How [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Adjustments to transaction price for performance obligations				1,000,000
Collaborative Arrangements [Member] | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. [Member] | Joint Development Committee [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Unrecognized amount of transaction price allocated to performance obligation				100,000
Collaborative Arrangements [Member] | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. [Member] | Maximum [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential development and regulatory milestone payments	$ 22,000,000
Collaborative Arrangements [Member] | Newsoara Biopharma Co., Ltd. [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fee received		$ 2,000,000
Potential development and regulatory milestone payments		$ 58,500,000
Collaboration revenue recognized						1,000,000
Collaborative Arrangements [Member] | Newsoara Biopharma Co., Ltd. [Member] | License And Technology Transfer Services [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized from change in estimated transaction prices				1,000,000		$ 1,000,000
Collaborative Arrangements [Member] | Anteris Bio, Inc. [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fee received				2,000,000
Potential development and regulatory milestone payments				151,000,000
Collaborative Arrangements [Member] | Anteris Bio, Inc. [Member] | License and Technology Transfer Services of Chemistry and Manufacturing Know-How [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License fee received				2,000,000
Collaboration revenue recognized				0
Equity interest received				4,200,000
Collaborative Arrangements [Member] | JDRF [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Maximum research funding receivable achievement based on research and development milestones			$ 3,400,000
Maximum funding percentage of research and development milestones			50.00%
Funding received				3,400,000
Research and development				$ 3,400,000

Collaboration Agreements - Summ

Collaboration Agreements - Summary of Contract Liabilities Related to Company's Collaboration Agreements (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred Revenue Disclosure [Abstract]
Current portion of contract liabilities	$ 35	$ 31
Contract liabilities, net of current portion		1,009
Total contract liabilities	$ 35	$ 1,040

Share-Based Compensation - Addi

Share-Based Compensation - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Jul. 29, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Non-qualified stock option awards vesting period	3 years	3 years
Non-qualified stock option awards expiration term	10 years	10 years
Compensation expense related to share-based awards	$ 2,356,000	$ 1,009,000	$ 1,518,000
Tax benefit related to stock option awards	$ 0	$ 0
Stock options cancelled	375,000
Share-based compensation expense	$ 500,000
Stock Option [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation cost related to non-vested share-based compensation arrangements	$ 3,300,000
Weighted average period to recognize unrecognized share-based compensation cost	2 years 7 months 6 days
Weighted average grant date fair value of options granted	$ 1.23	$ 1.91	$ 2.28
Increase Time Period To Exercise Options [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Purchase of common stock	1,190,263
Accelerate Vesting At Termination Date [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Purchase of common stock	616,667
Class A Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Common stock par value	$ 0.01	$ 0.01		$ 0.01
Class A Common Stock [Member] | Steve Holcombe [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Purchase of common stock	2,498,635
Common stock par value	$ 1.47
2015 Omnibus Equity Incentive Plan [Member] | Class A Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Maximum number of shares to be awarded	7,000,000

Share-Based Compensation - Assu

Share-Based Compensation - Assumptions Used to Estimate Fair Value of Stock Option Awards Granted (Detail)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Schedule of Share Based Compensation Valuation Assumptions [Line Items]
Expected dividend yield	0.00%	0.00%	0.00%
Minimum [Member]
Schedule of Share Based Compensation Valuation Assumptions [Line Items]
Expected volatility	118.75%	120.37%	115.29%
Expected life of option, in years	5 years 9 months 18 days	5 years 8 months 12 days	5 years 3 months 18 days
Risk-free interest rate	1.00%	0.39%	1.58%
Maximum [Member]
Schedule of Share Based Compensation Valuation Assumptions [Line Items]
Expected volatility	122.17%	121.43%	120.15%
Expected life of option, in years	6 years	6 years	6 years
Risk-free interest rate	1.34%	0.53%	2.64%

Share-Based Compensation - Summ

Share-Based Compensation - Summary of Stock Award Activity for the Period (Detail)	12 Months Ended
	Dec. 31, 2021$ / sharesshares
Share Based Arrangements To Obtain Goods And Services [Abstract]
Number of Shares, Awards outstanding, Beginning balance | shares	4,453,357
Number of Shares, Granted | shares	3,368,635
Number of Shares, Exercised | shares	(20,833)
Number of Shares, Forfeited | shares	(745,124)
Number of Shares, Awards outstanding, Ending balance | shares	7,056,035
Number of Shares, Options exercisable | shares	2,908,180
Number of Shares, Options exercisable, Weighted average remaining contractual term	6 years 3 months 18 days
Number of Shares, Options vested and expected to vest | shares	5,960,235
Number of Shares, Options vested and expected to vest, Weighted average remaining contractual term	7 years 10 months 24 days
Weighted-Average Exercise Price, Awards outstanding, Beginning balance | $ / shares	$ 4.41
Weighted-Average Exercise Price, Granted | $ / shares	1.43
Weighted Average Exercised | $ / shares	2.24
Weighted-Average Exercise Price, Forfeited | $ / shares	2.60
Weighted-Average Exercise Price, Awards outstanding, Ending balance | $ / shares	3.19
Weighted-Average Exercise Price, Options exercisable | $ / shares	5.50
Weighted-Average Exercise Price, Options vested and expected to vest | $ / shares	$ 3.50

Share-Based Compensation - Su_2

Share-Based Compensation - Summary of Compensation Expense Related to Grants of Stock Options (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total share-based compensation expense	$ 2,356	$ 1,009	$ 1,518
Research and Development [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total share-based compensation expense	599	348	522
General and Administrative [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total share-based compensation expense	$ 1,757	$ 661	$ 996

Prepaid Expenses and Other Cu_3

Prepaid Expenses and Other Current Assets - Summary of Prepaid Expenses and Other Current Assets (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Prepaid Expense And Other Assets Current [Abstract]
Prepaid insurance	$ 863	$ 771
Prepaid taxes	97	129
Deferred financing costs	135
Prepaid - other	954	39
Total	$ 2,049	$ 939

Property and Equipment - Summar

Property and Equipment - Summary of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Total property and equipment	$ 583	$ 583
Less: accumulated depreciation and amortization	(305)	(216)
Property and equipment, net	278	367
Leasehold Improvements [Member]
Property Plant And Equipment [Line Items]
Total property and equipment	406	406
Computers and Hardware [Member]
Property Plant And Equipment [Line Items]
Total property and equipment	48	48
Software [Member]
Property Plant And Equipment [Line Items]
Total property and equipment	80	80
Furniture and Office Equipment [Member]
Property Plant And Equipment [Line Items]
Total property and equipment	$ 49	$ 49

Property and Equipment - Additi

Property and Equipment - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Property Plant And Equipment [Abstract]
Depreciation expense	$ 89	$ 94	$ 39

Investments - Additional Inform

Investments - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Equity Securities With Readily Determinable Fair Value [Line Items]
Date of agreement	Dec. 11, 2020
Unrealized Gain (Loss) on Investments	$ 2,448	$ 4,245
Reneo [Member]
Equity Securities With Readily Determinable Fair Value [Line Items]
Unrealized Gain (Loss) on Investments	$ 2,400
Measurement Input Price Volatility [Member]
Equity Securities With Readily Determinable Fair Value [Line Items]
Expected volatility	125
Measurement Input Risk Free Interest Rate [Member]
Equity Securities With Readily Determinable Fair Value [Line Items]
Expected volatility	0.37
Maximum [Member]
Equity Securities With Readily Determinable Fair Value [Line Items]
Equity method investments, ownership percentage	20.00%

Investments - Schedule of Equit

Investments - Schedule of Equity Investments with and without Readily Determinable Fair Values Assessed (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Equity Securities Without Readily Determinable Fair Value [Line Items]
Equity Securities without Readily Determinable Fair Value, Amount	$ 9,173	$ 6,725
Reneo [Member] | Common Stock [Member]
Equity Securities Without Readily Determinable Fair Value [Line Items]
Equity Investments with Readily Determinable Fair Value, Amount	4,928
Equity Securities without Readily Determinable Fair Value, Amount		2,480
Anteris Bio, Inc. [Member] | Preferred Stock [Member]
Equity Securities Without Readily Determinable Fair Value [Line Items]
Equity Securities without Readily Determinable Fair Value, Amount	$ 4,245	$ 4,245

Accounts Payable and Accrued _3

Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Payables And Accruals [Abstract]
Accounts payable	$ 1,876	$ 1,925
Accrued development costs	2,790	2,581
Accrued compensation and related costs	3,202	1,594
Accrued other	155	20
Total	$ 8,023	$ 6,120

Leases - Additional Information

Leases - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Leases [Abstract]
Weighted average incremental borrowing rate	13.10%	13.10%
Remaining operating lease term	3 years 1 month 6 days	4 years 1 month 6 days
Operating lease cost	$ 200,000	$ 200,000	$ 400,000
Cash paid for operating lease	$ 300,000
Lease expiration month and year	2019-12
Lease exit costs		0
Asset retirement obligation		$ 300,000

Leases - Schedule of Maturities

Leases - Schedule of Maturities of Lease Liabilities for Operating Leases (Detail) $ in Thousands	Dec. 31, 2021USD ($)
Operating Lease Liabilities Payments Due [Abstract]
2022	$ 261
2023	268
2024	275
2025	23
Total lease payments	827
Less: imputed interest	(151)
Present value of lease liabilities	$ 676

Notes Payable - Schedule of Not

Notes Payable - Schedule of Notes Payable (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Debt Disclosure [Abstract]
Short-term financing	$ 256	$ 84
Total notes payable	256	84
Less: Current portion	$ (256)	$ (84)

Notes Payable - Additional Info

Notes Payable - Additional Information (Detail) - USD ($)	Mar. 24, 2017	Oct. 28, 2016	Mar. 31, 2017	Oct. 31, 2016	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Debt Instrument [Line Items]
Loan borrowed amount					$ 887,000	$ 500,000	$ 500,000
Loan and Security Agreement [Member] | LIBOR [Member]
Debt Instrument [Line Items]
Debt instrument, interest rate floor				0.50%
Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member]
Debt Instrument [Line Items]
Loan borrowed amount				$ 20,000,000
Debt instrument, interest rate floor				10.50%
Variable rate basis							one-month LIBOR
Interest rate description					Each loan tranche bore interest at a floating rate equal to 10.5% plus the amount by which the one-month LIBOR exceeds 0.5%.
Warrant exercise price condition					exercise price equal to the lower of (a) the volume weighted average price per share of the Company’s Class A Common Stock, as reported on the principal stock exchange on which the Company’s Class A Common Stock is listed, for 10 trading days prior to the issuance of the applicable Warrants or (b) the closing price of a share of the Company’s Class A Common Stock on the trading day prior to the issuance of the applicable Warrants
Warrants expiration period		7 years
Interest expense related to loan agreement					$ 0	$ 700,000	$ 1,800,000
Loan agreement termination period					2020-12
Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member] | Tranche One [Member]
Debt Instrument [Line Items]
Loan borrowed amount				$ 12,500,000
Debt instrument, payment terms					The Company borrowed the first tranche of $12.5 million upon close of the Loan Agreement in October 2016.  The first tranche required only monthly interest payments until May 1, 2018, followed by equal monthly payments of principal plus accrued interest through the scheduled maturity date on May 1, 2020.
Debt instrument, final payment				$ 800,000
Debt instrument, maturity date				May 1, 2020
Debt instrument, frequency of periodic Payment					monthly
Warrants to purchase shares of common stock		152,580
Exercise price of warrants		$ 6.39
Warrant shares percentage issued of loan amount		6.00%
Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member] | Tranche Two [Member]
Debt Instrument [Line Items]
Loan borrowed amount			$ 7,500,000
Debt instrument, payment terms					The Company borrowed the second tranche of $7.5 million in March 2017.  The second tranche requires only monthly interest payments until October 1, 2018, followed by equal monthly payments of principal plus accrued interest through the scheduled maturity date on October 1, 2020.
Debt instrument, final payment				$ 500,000
Debt instrument, maturity date				Oct. 1, 2020
Debt instrument, frequency of periodic Payment					monthly
Warrants to purchase shares of common stock	38,006
Exercise price of warrants	$ 5.92
Warrant shares percentage issued of loan amount	3.00%	3.00%
Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member] | Tranche One And Two [Member]
Debt Instrument [Line Items]
Debt instrument, payment terms					The total amount of the payment was increased to $0.8 million as a result of the Second and Third Amendments.  For each of the first and second tranches, the combined Second and Third Amendment required only monthly interest payments on the outstanding principal balance for the amounts due from April 1, 2020, through August 1, 2020.
Debt instrument, final payment					$ 800,000

Commitments and Contingencies -

Commitments and Contingencies - Additional Information (Detail) - Novo License Agreement [Member] - USD ($)	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019	Feb. 28, 2007
Developmental And Regulatory Milestone Payment | Maximum [Member] | Other Indication [Member]
Commitments And Contingencies [Line Items]
Potential milestone payment				$ 115,000,000
Developmental And Regulatory Milestone Payment | Maximum [Member] | Type 1 Diabetes [Member]
Commitments And Contingencies [Line Items]
Potential milestone payment				9,000,000
Developmental And Regulatory Milestone Payment | Maximum [Member] | Type 2 Diabetes [Member]
Commitments And Contingencies [Line Items]
Potential milestone payment				50,500,000
Sales-based Milestones Payment [Member]
Commitments And Contingencies [Line Items]
Potential milestone payment				$ 75,000,000
Satisfaction of Milestone Payment [Member]
Commitments And Contingencies [Line Items]
Potential milestone payment	$ 2,000,000	$ 0	$ 0

Stockholders' Equity - Addition

Stockholders' Equity - Additional Information (Detail)

May 04, 2021shares

Dec. 08, 2020USD ($)$ / sharesshares

Nov. 24, 2020USD ($)$ / sharesshares

Apr. 30, 2020USD ($)$ / shares

Mar. 24, 2017$ / sharesshares

Oct. 28, 2016$ / sharesshares

Dec. 31, 2021USD ($)Vote$ / sharesshares

Dec. 31, 2020USD ($)$ / sharesshares

Dec. 31, 2019USD ($)

Jun. 25, 2021USD ($)

Jan. 14, 2021USD ($)

Jul. 29, 2015$ / sharesshares

Class Of Stock [Line Items]

Preferred stock, shares authorized

50,000,000

Preferred stock par value | $ / shares

$ 0.01

Capital stock, shares authorized

350,000,000

250,000,000

Common stock, voting rights

Holders of Class A Common Stock and Class B Common Stock will be entitled to one vote for each share held on all matters submitted to stockholders for their vote or approval.

Net proceeds from issuance of common stock | $

$ 26,757,000

$ 14,426,000

$ 5,443,000

Issuance of Class A Common Stock under LPC Agreement | $

9,087,000

1,930,000

Change in fair value of consideration warrants expense | $

1,600,000

(300,000)

$ 800,000

Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member]

Class Of Stock [Line Items]

Warrants expiration period

7 years

Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member] | Tranche One [Member]

Class Of Stock [Line Items]

Warrants to purchase shares of common stock

152,580

Exercise price of warrants | $ / shares

$ 6.39

Warrant shares percentage issued of loan amount

6.00%

Loan and Security Agreement [Member] | Horizon Technology Finance Corporation and Silicon Valley Bank [Member] | Tranche Two [Member]

Class Of Stock [Line Items]

Warrants to purchase shares of common stock

38,006

Exercise price of warrants | $ / shares

$ 5.92

Warrant shares percentage issued of loan amount

3.00%

3.00%

Cantor Fitzgerald [Member] | ATM Offering [Member]

Class Of Stock [Line Items]

Gross proceeds from issuance of common stock | $

18,200,000

13,000,000

Net proceeds from issuance of common stock | $

$ 17,700,000

$ 12,500,000

LPC Purchase Agreement [Member]

Class Of Stock [Line Items]

Agreement term

36 months

Class A Common Stock [Member]

Class Of Stock [Line Items]

Common stock, shares authorized

200,000,000

200,000,000

100,000,000

100,000,000

Common stock par value | $ / shares

$ 0.01

$ 0.01

$ 0.01

Increase in shares authorized

100,000,000

Common stock, vote per share | Vote

1

Common stock, shares outstanding

66,942,777

54,050,710

Class A Common Stock [Member] | Cantor Fitzgerald [Member] | ATM Offering [Member]

Class Of Stock [Line Items]

Common stock par value | $ / shares

$ 0.01

Aggregate offering price | $

$ 50,000,000

$ 5,500,000

Shares sold

8,929,147

5,480,941

Class A Common Stock [Member] | Cantor Fitzgerald [Member] | ATM Offering [Member] | Maximum [Member]

Class Of Stock [Line Items]

Aggregate offering price | $

$ 13,000,000

Class A Common Stock [Member] | LPC Purchase Agreement [Member]

Class Of Stock [Line Items]

Shares sold

963,855

425,725

Shares registered under the LPC agreement

5,331,306

Percentage of aggregate offering price

1.50%

Share price | $ / shares

$ 2.08

Aggregate gross purchase price | $

$ 2,000,000

Issuance of Class A Common Stock under LPC agreement shares

3,941,726

Issuance of Class A Common Stock under LPC Agreement | $

$ 9,100,000

Maximum obligation for number of shares issued per day

2,000,000

Purchase price for shares

The purchase price for shares of Class A common stock to be purchased by Lincoln Park under a Regular Purchase will be equal to the lower of (in each case, subject to the adjustments described in the LPC Purchase Agreement): (i) the lowest sale price for the Class A common stock on the applicable purchase date and (ii) the arithmetic average of the three lowest closing sales prices for the Class A common stock during the 10 consecutive trading days prior to the purchase date

Common stock, shares outstanding

73,880,351

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Maximum [Member]

Class Of Stock [Line Items]

Aggregate offering price | $

$ 47,000,000

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Regular Purchase Share Limit [Member] | Maximum [Member]

Class Of Stock [Line Items]

Number of shares issued per day

250,000

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Regular Purchase Share Limit Two [Member] | Maximum [Member]

Class Of Stock [Line Items]

Increase in number of shares issued per day

275,000

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Regular Purchase Share Limit Two [Member] | Minimum [Member]

Class Of Stock [Line Items]

Share price | $ / shares

$ 4

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Regular Purchase Share Limit Three [Member] | Maximum [Member]

Class Of Stock [Line Items]

Increase in number of shares issued per day

300,000

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Regular Purchase Share Limit Three [Member] | Minimum [Member]

Class Of Stock [Line Items]

Share price | $ / shares

$ 5

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Additional Accelerated [Member]

Class Of Stock [Line Items]

Percentage of number of shares issued during period

300.00%

Percentage of number of common stock shares traded during period

30.00%

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Additional Accelerated [Member] | Maximum [Member]

Class Of Stock [Line Items]

Share price as a percentage of the volume weighted average price

97.00%

Class A Common Stock [Member] | LPC Purchase Agreement [Member] | Exchange Cap [Member] | Maximum [Member]

Class Of Stock [Line Items]

Maximum number of shares to be issued as percentage of outstanding

19.99%

Maximum number of shares to be issued

14,768,682

Class A Common Stock [Member] | Lincoln Park Capital Fund, LLC and Affiliates [Member] | Maximum [Member]

Class Of Stock [Line Items]

Ownership percentage by noncontrolling owners

9.99%

Class B Common Stock [Member]

Class Of Stock [Line Items]

Common stock, shares authorized

100,000,000

100,000,000

100,000,000

Common stock par value | $ / shares

$ 0.01

$ 0.01

$ 0.01

Common stock, vote per share | Vote

1

Common stock, shares outstanding

23,093,860

23,094,221

Common Stock [Member]

Class Of Stock [Line Items]

Common stock, shares authorized

300,000,000

200,000,000

Stockholders' Equity - Assumpti

Stockholders' Equity - Assumptions Used to Calculate Fair Value of Warrants (Detail) - Letter Agreement Warrants [Member]	Dec. 23, 2019yr	Sep. 26, 2019yr	Dec. 11, 2018yr	Jul. 30, 2018yr	Dec. 05, 2017yr
Expected Volatility [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Measurement input	110.41	110.35	104.46	95.29	90
Expected Life of Option, in Years [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Measurement input	7	7	7	7	7
Risk-Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Measurement input	1.84	1.65	2.77	2.94	2.80
Expected Dividend Yield [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Measurement input	0	0	0	0	0

Redeemable Noncontrolling Int_3

Redeemable Noncontrolling Interest - Additional Information (Detail) $ in Millions	12 Months Ended
	Dec. 31, 2021USD ($)	Dec. 31, 2020USD ($)
Noncontrolling Interest [Line Items]
Redemption amount of noncontrolling interest	$ 25	$ 83.9
Class A Common Stock [Member]
Noncontrolling Interest [Line Items]
Number of days used to determine exchange value based on weighted average price of Class A common stock	20 days
Class A Common Stock [Member] | Exchange of Redeemable Non controlling Interest To Class A Common Stock [Member]
Noncontrolling Interest [Line Items]
Stock conversion ratio	1
vTv Therapeutics LLC [Member]
Noncontrolling Interest [Line Items]
Noncontrolling interest ownership percentage	25.60%

Redeemable Noncontrolling Int_4

Redeemable Noncontrolling Interest - Summary of Net Income Attributable to Vtv Therapeutics Inc (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Noncontrolling Interest [Abstract]
Net loss attributable to vTv Therapeutics Inc. common shareholders	$ (12,987)	$ (8,499)	$ (17,913)
Increase in vTv Therapeutics Inc. accumulated deficit for purchase of LLC Units as a result of common stock issuances	(5,084)	(8,943)	(17,971)
Change from net loss attributable to vTv Therapeutics Inc. common shareholders and transfers to noncontrolling interest	$ (18,071)	$ (17,442)	$ (35,884)

Related-Party Transactions - Ad

Related-Party Transactions - Additional Information (Detail)	12 Months Ended
	Dec. 31, 2021shares
Class A Common Stock [Member] | Exchange of Redeemable Non controlling Interest To Class A Common Stock [Member]
Related Party Transaction [Line Items]
Stock conversion ratio	1
MacAndrews & Forbes Incorporated [Member]
Related Party Transaction [Line Items]
Ownership percentage of majority owner	66.20%
Amount of cash savings percentage	85.00%
Description of tax receivable agreement	The Tax Receivable Agreement among the Company, M&F TTP Holdings Two LLC, as successor in interest to vTv Therapeutics Holdings (“M&F”) and M&F TTP Holdings LLC provides for the payment by the Company to M&F (or certain of its transferees or other assignees) of 85% of the amount of cash savings, if any, in U.S. federal, state and local income tax or franchise tax that the Company actually realizes (or, in some circumstances, the Company is deemed to realize) as a result of (a) the exchange of Class B Common Stock, together with the corresponding number of vTv Units, for shares of the Company’s Class A Common Stock (or for cash), (b) tax benefits related to imputed interest deemed to be paid by the Company as a result of the Tax Receivable Agreement and (c) certain tax benefits attributable to payments under the Tax Receivable Agreement.
MacAndrews & Forbes Incorporated [Member] | Class B Common Stock [Member]
Related Party Transaction [Line Items]
Shares held by related party	23,084,267
MacAndrews & Forbes Incorporated [Member] | Class A Common Stock [Member]
Related Party Transaction [Line Items]
Shares held by related party	36,519,212
MacAndrews & Forbes Incorporated [Member] | Class A Common Stock [Member] | Exchange of Redeemable Non controlling Interest To Class A Common Stock [Member]
Related Party Transaction [Line Items]
Stock conversion ratio	1

Related-Party Transactions - Su

Related-Party Transactions - Summary of Terms of Letter Agreements (Detail) - MacAndrews & Forbes Incorporated [Member] - Class A Common Stock [Member] - USD ($) $ / shares in Units, $ in Millions	Dec. 31, 2019	Sep. 26, 2019	Mar. 18, 2019	Dec. 11, 2018	Jul. 30, 2018	Dec. 05, 2017
2017 Letter Agreement [Member]
Class Of Warrant Or Right [Line Items]
Aggregate dollar value to be sold under agreement						$ 10
Specified purchase price per share						$ 4.38
Expiration date of letter agreement						Dec. 5, 2018
Shares available to be issued under related warrants						198,267
Exercise price of related warrants						$ 5.04
Expiration date of related warrants						Dec. 5, 2024
Total shares issued as of December 31, 2021						2,283,105
2018 Letter Agreement [Member]
Class Of Warrant Or Right [Line Items]
Aggregate dollar value to be sold under agreement				$ 10	$ 10
Specified purchase price per share				$ 1.84	$ 1.33
Expiration date of letter agreement				Dec. 11, 2019	Jul. 30, 2019
Shares available to be issued under related warrants				340,534	518,654
Exercise price of related warrants				$ 2.12	$ 1.53
Expiration date of related warrants				Dec. 11, 2025	Jul. 30, 2025
Total shares issued as of December 31, 2021				5,434,783	7,518,797
2019 Letter Agreement [Member]
Class Of Warrant Or Right [Line Items]
Aggregate dollar value to be sold under agreement	$ 10	$ 10	$ 9
Specified purchase price per share	$ 1.60	$ 1.46	$ 1.65
Expiration date of letter agreement	Dec. 23, 2020	Sep. 26, 2020	Mar. 18, 2020
Shares available to be issued under related warrants	365,472	400,990
Exercise price of related warrants	$ 1.84	$ 1.68
Expiration date of related warrants	Dec. 23, 2026	Sep. 26, 2026
Total shares issued as of December 31, 2021	6,250,000	6,849,316	5,454,546

Employee Benefit Plan - Additio

Employee Benefit Plan - Additional Information (Detail) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Compensation And Employee Benefit Plans [Abstract]
Percentage of employer contribution	50.00%
Maximum annual contribution per employee	6.00%
Contributions made by employer	$ 0.1	$ 0.1	$ 0.1

Income Taxes - Additional Infor

Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Taxes [Line Items]
Income tax provision	$ 115,000	$ 0	$ 100,000
Increase in valuation allowance	2,900,000
Uncertain tax positions	0
Increase decrease in uncertain tax position reasonably possible	0
Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 95,900,000
Net operating loss carryforwards, limitations on use	Approximately, $40.0 million of these carryforwards expire in varying amounts starting in 2035 to 2037, if not utilized and are available to offset 100% of future taxable income.  The remaining $55.9 million may be carried forward indefinitely but are only available to offset 80% of future taxable income.  The Company has federal research and development tax credits of $1.8 million which expire in varying amounts starting in 2035 to 2040.
State and Local Jurisdiction [Member]
Income Taxes [Line Items]
Earliest open tax year	2017 2018 2019 2020 2021
Minimum [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards expiration date	2035
Maximum [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards expiration date	2037
Expire in 2035 to 2037 [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 40,000,000
Maximum percentage of taxable income limited to offset by net operating loss carryforwads.	100.00%
Indefinite [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 55,900,000
Maximum percentage of taxable income limited to offset by net operating loss carryforwads.	80.00%
Expire In 2035 to 2040 [Member] | Research And Development [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 1,800,000
Expire In 2035 to 2040 [Member] | Research And Development [Member] | Minimum [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards expiration date	2035
Expire In 2035 to 2040 [Member] | Research And Development [Member] | Maximum [Member] | Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards expiration date	2040
M&F TTP Holdings LLC [Member]
Income Taxes [Line Items]
Amount of cash savings percentage	85.00%

Income Taxes - Schedule of Effe

Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Tax Disclosure [Abstract]
U.S. statutory tax benefit	$ (3,699,000)	$ (2,688,000)	$ (4,586,000)
Partnership income (federal) not subject to tax to the Company	996,000	904,000	1,868,000
Foreign withholding tax	91,000		79,000
State taxes (net of federal benefit)	(14,000)	(13,000)	134,000
Research and development tax credit	(173,000)	(138,000)	(231,000)
Other	10,000	75,000	(81,000)
Change in valuation allowance	2,904,000	1,860,000	2,917,000
Provision for income taxes	$ 115,000	$ 0	$ 100,000
Effective income tax rate	(0.70%)	0.00%	(0.50%)

Income Taxes - Schedule of Net

Income Taxes - Schedule of Net Deferred Tax Assets/(Liabilities) (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Net operating loss carryforwards	$ 20,909	$ 17,338
R&D Tax Credit carryforwards	1,755	1,587
Investment in partnerships liabilities	(2,353)	(1,520)
Charitable contributions	11	12
Total deferred tax assets	20,322	17,417
Valuation allowance	$ (20,322)	$ (17,417)

Restructuring - Additional Info

Restructuring - Additional Information (Detail) $ in Millions	12 Months Ended
	Dec. 31, 2021USD ($)
Restructuring Cost And Reserve [Line Items]
Restructuring costs	$ 1.6
Cash payments	$ 0.1
Restructuring initiation month and year	2021-12
Restructuring workforce employee affected percentage	65.00%
Accrued severance and benefits costs	$ 1.5
Research and Development [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	0.7
General and Administrative [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring costs	0.9
Retirement and Consulting Agreement [Member]
Restructuring Cost And Reserve [Line Items]
Restructuring reserve	0.4
Restructuring costs	0.2
Cash payments	0.1
Additional severance costs	0.5
Additional consulting fees	$ 0.2

Net Loss per Share - Reconcilia

Net Loss per Share - Reconciliation of the Numerator and Denominator Used in the Calculation of Basic and Diluted Net Loss per Share of Class A Common Stock (Detail) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Numerator:
Net loss	$ (17,731)	$ (12,802)	$ (21,938)
Less: Net loss attributable to noncontrolling interests	(4,744)	(4,303)	(8,894)
Net loss attributable to vTv Therapeutics Inc.	(12,987)	(8,499)	(13,044)
Less: Deemed distribution to related party (Note 13)			(4,869)
Net loss attributable to common shareholders of vTv Therapeutics Inc., basic and diluted	$ (12,987)	$ (8,499)	$ (17,913)
Class A Common Stock [Member]
Denominator:
Weighted average vTv Therapeutics Inc. Class A Common Stock, basic and diluted	60,732,636	47,137,917	30,292,030
Net loss per share of vTv Therapeutics Inc. Class A Common Stock, basic and diluted	$ (0.21)	$ (0.18)	$ (0.59)

Net Loss per Share - Schedule o

Net Loss per Share - Schedule of Potentially Dilutive Securities not Included in Calculation of Dilutive Net Loss per Share (Detail) - shares		12 Months Ended
		Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share		32,164,398	29,562,081	33,901,534
Class B Common Stock [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share	[1]	23,093,860	23,094,221	23,094,221
Common Stock Options Granted Under the Plan [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share		7,056,035	4,453,357	2,531,143
Restricted Stock Units [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share				11,667
Common Stock Options Granted Under the Letter Agreement [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share				6,250,000
Common Stock Warrants [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Potentially dilutive securities not included in calculation of dilutive net loss per share		2,014,503	2,014,503	2,014,503
[1]	Shares of Class B Common Stock do not share in the Company’s earnings and are not participating securities.  Accordingly, separate presentation of loss per share of Class B Common Stock under the two-class method has not been provided.  Each share of Class B Common Stock (together with a corresponding vTv Unit) is exchangeable for one share of Class A Common Stock.

Fair Value of Financial Instr_3

Fair Value of Financial Instruments - Summarizes the Conclusions Reached Regarding Fair Value Measurements (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Significant Unobservable Inputs (Level 3) [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Balance at January 1	$ 2,871	$ 2,601	$ 2,436
Net Change in fair value included in earnings	(1,609)	270	(827)
Purchases / Issuance			992
Balance at December 31,	1,262	2,871	2,601
Significant Unobservable Inputs (Level 3) [Member] | Warrant Liability, Related Party [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Balance at January 1	2,871	2,601	2,436
Net Change in fair value included in earnings	(1,609)	270	(827)
Purchases / Issuance			992
Balance at December 31,	1,262	2,871	$ 2,601
Fair Value, Measurements, Recurring [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	4,928
Total	1,262	2,871
Fair Value, Measurements, Recurring [Member] | Warrant Liability, Related Party [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	1,262	2,871
Fair Value, Measurements, Recurring [Member] | Equity Securities With Readily Determinable Fair Value [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	4,928
Fair Value, Measurements, Recurring [Member] | Quoted Prices in Active Markets for Identical Asset (Level 1) [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	4,928
Fair Value, Measurements, Recurring [Member] | Quoted Prices in Active Markets for Identical Asset (Level 1) [Member] | Equity Securities With Readily Determinable Fair Value [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	4,928
Fair Value, Measurements, Recurring [Member] | Significant Unobservable Inputs (Level 3) [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	1,262	2,871
Fair Value, Measurements, Recurring [Member] | Significant Unobservable Inputs (Level 3) [Member] | Warrant Liability, Related Party [Member]
Fair Value Of Assets And Liabilities Measured On Recurring Basis [Line Items]
Total	$ 1,262	$ 2,871

Fair Value of Financial Instr_4

Fair Value of Financial Instruments - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Fair Value Disclosures [Abstract]
Fair value equity transfers in and out of level 3 instruments	$ 0	$ 0	$ 0
Fair value equity transfers between level 1 and level 2 instruments	$ 0	$ 0	$ 0

Fair Value of Financial Instr_5

Fair Value of Financial Instruments - Significant Inputs Utilized in the Valuation of Letter Agreement Warrants (Detail) - Letter Agreement Warrants [Member]	Dec. 31, 2021	Dec. 31, 2020	Dec. 23, 2019	Sep. 26, 2019	Dec. 11, 2018	Jul. 30, 2018	Dec. 05, 2017
Expected Volatility [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants			110.41	110.35	104.46	95.29	90
Risk-Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants			1.84	1.65	2.77	2.94	2.80
Minimum [Member] | Expected Volatility [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	82.68	120.53
Minimum [Member] | Risk-Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	0.95	0.26
Maximum [Member] | Expected Volatility [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	142.86	142.07
Maximum [Member] | Risk-Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	1.26	0.50
Weighted Average [Member] | Expected Volatility [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	128.13	128.16
Weighted Average [Member] | Risk-Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis Valuation Techniques [Line Items]
Inputs utilized in the valuation of warrants	1.15	0.39

Subsequent Events - Additional

Subsequent Events - Additional Information (Detail) - USD ($)	Mar. 29, 2022	Mar. 01, 2022	Dec. 31, 2021	Dec. 31, 2020
Subsequent Event [Line Items]
Outstanding stock options			7,056,035	4,453,357
Stock options, award vesting period			3 years	3 years
Stock options granted in period			3,368,635
Stock options exercise price			$ 1.43
Subsequent Event [Member] | Nelson Employment Agreement [Member]
Subsequent Event [Line Items]
Minimum amount of base salary		$ 200,000
Cash bonus of base salary percentage		100.00%
Subsequent Event [Member] | Nelson Employment Agreement [Member] | Class A Common Stock [Member]
Subsequent Event [Line Items]
Stock options, award vesting period		3 years
Stock options granted in period		500,000
Stock options exercise price		$ 0.8060
Stock options will vest on effective date		125,000
Options vest ratably every three months over vesting period		375,000
Forecast [Member] | Strategic Advisor [Member]
Subsequent Event [Line Items]
Outstanding stock options	624,659
Stock options, award vesting period	15 months