Exhibit 15.1
Consent of Independent Registered Public Accounting Firm
We hereby consent to the incorporation by reference in the Registration Statement on Form F-3 No. 333-257705 of Santander UK Group Holdings plc of our report dated 5 March, 2024 relating to the financial statements, which appears in this Form 20-F.
/s/ PricewaterhouseCoopers LLP
London, United Kingdom
5 March, 2024
1