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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements on FormS-8(Nos. 333-220866 and333-223992) and FormS-3 (No.333-227638) of Deciphera Pharmaceuticals, Inc. of our report dated March 14, 2019 relating to the financial statements, which appears in this Form10-K.
/s/ PricewaterhouseCoopers LLP
Boston, Massachusetts
March 14, 2019