ARK Investment Management 13F-HR Quarterly holdings report by institutional manager

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
Adobe Inc	Common Stock	00724F101	15,766	33,165	SH		SOLE		33,165	0	0
Aerojet Rocketdyne Holdings Inc	Common Stock	007800105	4,228	90,029	SH		SOLE		90,029	0	0
AeroVironment Inc	Common Stock	008073108	65,079	560,739	SH		SOLE		560,739	0	0
Alibaba Group Holding Ltd	ADR	01609W102	133,958	590,826	SH		SOLE		590,826	0	0
Align Technology Inc	Common Stock	016255101	6,615	12,215	SH		SOLE		12,215	0	0
Allegheny Technologies Inc	Common Stock	01741R102	746	35,406	SH		SOLE		35,406	0	0
Alphabet Inc	Common Stock	02079K107	119,041	57,546	SH		SOLE		57,546	0	0
Altair Engineering Inc	Common Stock	021369103	24,201	386,786	SH		SOLE		386,786	0	0
Amazon.com Inc	Common Stock	023135106	43,063	13,918	SH		SOLE		13,918	0	0
AMETEK Inc	Common Stock	031100100	7,197	56,347	SH		SOLE		56,347	0	0
ANSYS Inc	Common Stock	03662Q105	57,539	169,452	SH		SOLE		169,452	0	0
Apple Inc	Common Stock	037833100	72,562	594,039	SH		SOLE		594,039	0	0
AquaBounty Technologies Inc	Common Stock	03842K200	48,557	7,247,378	SH		SOLE		7,247,378	0	0
Arcturus Therapeutics Holdings Inc	Common Stock	03969T109	137,607	3,331,889	SH		SOLE		3,331,889	0	0
Autodesk Inc	Common Stock	052769106	41,862	151,043	SH		SOLE		151,043	0	0
Baidu Inc	ADR	056752108	1,115,497	5,127,543	SH		SOLE		4,688,247	329,127	110,169
Renishaw PLC	Common Stock	G75006117	27,726	313,442	SH		SOLE		313,442	0	0
CareDx Inc	Common Stock	14167L103	303,738	4,460,824	SH		SOLE		4,460,824	0	0
Carpenter Technology Corp	Common Stock	144285103	750	18,218	SH		SOLE		18,218	0	0
Castle Biosciences Inc	Common Stock	14843C105	177,810	2,597,288	SH		SOLE		2,597,288	0	0
Cellectis SA	ADR	15117K103	103,425	5,117,526	SH		SOLE		5,117,526	0	0
Cerus Corp	Common Stock	157085101	153,507	25,541,955	SH		SOLE		23,600,810	616,222	1,324,923
Codexis Inc	Common Stock	192005106	143,786	6,281,617	SH		SOLE		6,281,617	0	0
Deere & Co	Common Stock	244199105	132,551	354,282	SH		SOLE		354,282	0	0
DuPont de Nemours Inc	Common Stock	26614N102	603	7,808	SH		SOLE		7,808	0	0
Eastman Chemical Co	Common Stock	277432100	658	5,978	SH		SOLE		5,978	0	0
Editas Medicine Inc	Common Stock	28106W103	367,581	8,751,923	SH		SOLE		7,487,570	1,033,435	230,918
ExOne Co/The	Common Stock	302104104	83,948	2,676,905	SH		SOLE		2,413,344	0	263,561
Facebook Inc	Common Stock	30303M102	90,429	307,029	SH		SOLE		307,029	0	0
FARO Technologies Inc	Common Stock	311642102	7,935	91,661	SH		SOLE		91,661	0	0
Fate Therapeutics Inc	Common Stock	31189P102	540,422	6,554,546	SH		SOLE		6,554,546	0	0
General Electric Co	Common Stock	369604103	5,483	417,583	SH		SOLE		417,583	0	0
Grayscale Bitcoin Trust BTC	Open-End Fund	389637109	434,141	8,675,881	SH		SOLE		8,011,293	658,408	6,180
Guardant Health Inc	Common Stock	40131M109	107,351	703,250	SH		SOLE		703,250	0	0
Guidewire Software Inc	Common Stock	40171V100	41,604	409,367	SH		SOLE		409,367	0	0
HDFC Bank Ltd	ADR	40415F101	42,452	546,426	SH		SOLE		546,426	0	0
HP Inc	Common Stock	40434L105	31,288	985,456	SH		SOLE		985,456	0	0
Hexcel Corp	Common Stock	428291108	745	13,307	SH		SOLE		13,307	0	0
HubSpot Inc	Common Stock	443573100	74,136	163,219	SH		SOLE		163,219	0	0
Incyte Corp	Common Stock	45337C102	242,847	2,988,149	SH		SOLE		2,988,149	0	0
Intellia Therapeutics Inc	Common Stock	45826J105	771,404	9,611,911	SH		SOLE		7,778,015	1,427,842	406,054
Interactive Brokers Group Inc	Common Stock	45841N107	219	3,002	SH		SOLE		3,002	0	0
Intercontinental Exchange Inc	Common Stock	45866F104	627,317	5,617,092	SH		SOLE		5,268,406	259,279	89,407
Intuit Inc	Common Stock	461202103	76,489	199,680	SH		SOLE		199,680	0	0
Intuitive Surgical Inc	Common Stock	46120E602	36,840	49,855	SH		SOLE		49,855	0	0
OC Oerlikon Corp AG	Common Stock	H59187106	5,364	462,333	SH		SOLE		462,333	0	0
Invitae Corp	Common Stock	46185L103	916,192	23,977,808	SH		SOLE		20,810,440	2,373,199	794,169
Ionis Pharmaceuticals Inc	Common Stock	462222100	231,197	5,142,271	SH		SOLE		5,142,271	0	0
Iovance Biotherapeutics Inc	Common Stock	462260100	624,546	19,726,650	SH		SOLE		18,981,913	466,145	278,592
Iridium Communications Inc	Common Stock	46269C102	427,150	10,355,147	SH		SOLE		9,466,700	705,771	182,676
JD.com Inc	ADR	47215P106	392,282	4,651,745	SH		SOLE		4,651,745	0	0
SGL Carbon SE	Common Stock	D6949M108	788	112,500	SH		SOLE		112,500	0	0
Kaiser Aluminum Corp	Common Stock	483007704	5,086	46,030	SH		SOLE		46,030	0	0
Komatsu Ltd	ADR	500458401	106,587	3,412,965	SH		SOLE		3,412,965	0	0
Kratos Defense & Security Solutions Inc	Common Stock	50077B207	143,000	5,241,941	SH		SOLE		5,241,941	0	0
Henkel AG & Co KGaA	Preference	D3207M110	689	5,962	SH		SOLE		5,962	0	0
Bertrandt AG	Common Stock	D1014N107	4,900	90,559	SH		SOLE		90,559	0	0
LendingClub Corp	Common Stock	52603A208	120,074	7,268,414	SH		SOLE		6,466,326	183,369	618,719
LendingTree Inc	Common Stock	52603B107	367,018	1,723,091	SH		SOLE		1,489,736	177,145	56,210
Dassault Systemes SE	Common Stock	F2457H472	27,110	126,494	SH		SOLE		126,494	0	0
Lincoln Electric Holdings Inc	Common Stock	533900106	4,863	39,556	SH		SOLE		39,556	0	0
Siemens AG	Common Stock	D69671218	5,410	32,880	SH		SOLE		32,880	0	0
Materialise NV	ADR	57667T100	267,533	7,441,821	SH		SOLE		7,177,635	75,126	189,060
MercadoLibre Inc	Common Stock	58733R102	188,842	128,277	SH		SOLE		119,102	9,175	0
Microsoft Corp	Common Stock	594918104	25,739	109,170	SH		SOLE		109,170	0	0
Bezeq The Israeli Telecommunication Corp Ltd	Common Stock	M2012Q100	6,297	5,896,764	SH		SOLE		5,896,764	0	0
Moog Inc	Common Stock	615394202	4,879	58,675	SH		SOLE		58,675	0	0
Danel Adir Yeoshua Ltd	Common Stock	M27013107	6,706	40,911	SH		SOLE		40,911	0	0
Hilan Ltd	Common Stock	M5299H123	6,311	133,407	SH		SOLE		133,407	0	0
Nano Dimension Ltd	ADR	63008G203	111,389	12,967,241	SH		SOLE		12,967,241	0	0
NanoString Technologies Inc	Common Stock	63009R109	217,825	3,314,947	SH		SOLE		3,193,514	121,433	0
Elbit Systems Ltd	Common Stock	M3760D101	49,232	344,279	SH		SOLE		344,279	0	0
SBI Holdings Inc/Japan	Common Stock	J6991H100	171	6,300	SH		SOLE		6,300	0	0
Partner Communications Co Ltd	Common Stock	M78465107	6,310	1,304,896	SH		SOLE		1,304,896	0	0
Netflix Inc	Common Stock	64110L106	69,642	133,501	SH		SOLE		133,501	0	0
Nice Ltd	ADR	653656108	4,905	22,504	SH		SOLE		22,504	0	0
FirstRand Ltd	Common Stock	S5202Z131	30	13,580	SH		SOLE		13,580	0	0
NVIDIA Corp	Common Stock	67066G104	216,303	405,115	SH		SOLE		405,115	0	0
NuVasive Inc	Common Stock	670704105	5,331	81,321	SH		SOLE		81,321	0	0
Matrix IT Ltd	Common Stock	M6859E153	6,376	266,444	SH		SOLE		266,444	0	0
Toray Industries Inc	Common Stock	J89494116	609	94,508	SH		SOLE		94,508	0	0
PTC Inc	Common Stock	69370C100	26,027	189,081	SH		SOLE		189,081	0	0
Pacific Biosciences of California Inc	Common Stock	69404D108	709,543	21,301,191	SH		SOLE		20,654,514	413,947	232,730
One Software Technologies Ltd	Common Stock	M75260113	6,327	48,615	SH		SOLE		48,615	0	0
PayPal Holdings Inc	Common Stock	70450Y103	407,881	1,679,629	SH		SOLE		1,558,336	110,602	10,691
Personalis Inc	Common Stock	71535D106	140,420	5,705,827	SH		SOLE		5,705,827	0	0
Straumann Holding AG	Common Stock	H8300N119	27,109	21,662	SH		SOLE		21,662	0	0
Pinduoduo Inc	ADR	722304102	112,078	837,156	SH		SOLE		837,156	0	0
Pinterest Inc	Common Stock	72352L106	229,119	3,094,949	SH		SOLE		3,094,949	0	0
Pluristem Therapeutics Inc	Common Stock	72940R300	17,121	3,589,322	SH		SOLE		3,589,322	0	0
Proto Labs Inc	Common Stock	743713109	444,978	3,654,854	SH		SOLE		3,126,453	386,403	141,998
Redhill Biopharma Ltd	ADR	757468103	5,678	775,698	SH		SOLE		775,698	0	0
Roku Inc	Common Stock	77543R102	1,628,082	4,997,644	SH		SOLE		4,429,891	447,706	120,047
Charles Schwab Corp/The	Common Stock	808513105	46,557	714,287	SH		SOLE		714,287	0	0
Seres Therapeutics Inc	Common Stock	81750R102	244,114	11,855,947	SH		SOLE		10,210,569	1,341,432	303,946
Shopify Inc	Common Stock	82509L107	1,187,853	1,073,523	SH		SOLE		992,842	64,581	16,100
Snap Inc	Common Stock	83304A106	165,966	3,173,955	SH		SOLE		3,173,955	0	0
Splunk Inc	Common Stock	848637104	1,194	8,813	SH		SOLE		8,813	0	0
Square Inc	Common Stock	852234103	2,492,627	10,978,316	SH		SOLE		10,014,653	737,361	226,302
Stryker Corp	Common Stock	863667101	4,662	19,138	SH		SOLE		19,138	0	0
Syros Pharmaceuticals Inc	Common Stock	87184Q107	57,684	7,711,724	SH		SOLE		7,032,971	186,593	492,160
Taiwan Semiconductor Manufacturing Co Ltd	ADR	874039100	47,019	397,524	SH		SOLE		397,524	0	0
Teladoc Health Inc	Common Stock	87918A105	2,621,595	14,424,180	SH		SOLE		13,420,301	771,257	232,622
Tencent Holdings Ltd	ADR	88032Q109	548,025	6,867,476	SH		SOLE		6,438,407	373,500	55,569
Teradyne Inc	Common Stock	880770102	350,086	2,877,103	SH		SOLE		2,779,946	58,658	38,499
Tesla Inc	Common Stock	88160R101	3,864,324	5,785,523	SH		SOLE		5,351,827	429,044	4,652
Teva Pharmaceutical Industries Ltd	ADR	881624209	5,768	499,844	SH		SOLE		499,844	0	0
Trade Desk Inc/The	Common Stock	88339J105	121,241	186,049	SH		SOLE		186,049	0	0
3D Systems Corp	Common Stock	88554D205	58,819	2,143,547	SH		SOLE		2,143,547	0	0
3M Co	Common Stock	88579Y101	731	3,792	SH		SOLE		3,792	0	0
Trimble Inc	Common Stock	896239100	218,609	2,810,249	SH		SOLE		2,810,249	0	0
Twilio Inc	Common Stock	90138F102	932,715	2,737,162	SH		SOLE		2,482,948	208,592	45,622
Twist Bioscience Corp	Common Stock	90184D100	748,798	6,045,520	SH		SOLE		5,796,015	139,968	109,537
2U Inc	Common Stock	90214J101	452,531	11,837,072	SH		SOLE		9,936,908	1,449,362	450,802
Ultra Clean Holdings Inc	Common Stock	90385V107	6,944	119,648	SH		SOLE		119,648	0	0
United Parcel Service Inc	Common Stock	911312106	4,887	28,750	SH		SOLE		28,750	0	0
Veracyte Inc	Common Stock	92337F107	409,429	7,617,287	SH		SOLE		7,404,211	213,076	0
Verisk Analytics Inc	Common Stock	92345Y106	634	3,588	SH		SOLE		3,588	0	0
Workday Inc	Common Stock	98138H101	81,293	327,228	SH		SOLE		327,228	0	0
Xilinx Inc	Common Stock	983919101	29,942	241,660	SH		SOLE		241,660	0	0
Xerox Holdings Corp	Common Stock	98421M106	687	28,303	SH		SOLE		28,303	0	0
Zillow Group Inc	Common Stock	98954M200	1,300,633	10,032,650	SH		SOLE		9,104,846	721,655	206,149
Koninklijke DSM NV	Common Stock	N5017D122	615	3,625	SH		SOLE		3,625	0	0
Arkema SA	Common Stock	F0392W125	660	5,435	SH		SOLE		5,435	0	0
MGI Digital Graphic Technology	Common Stock	F4090S113	23,904	412,659	SH		SOLE		412,659	0	0
Sandvik AB	Common Stock	W74857165	681	24,871	SH		SOLE		24,871	0	0
Hexagon AB	Common Stock	W40063104	7,031	76,061	SH		SOLE		76,061	0	0
Cellcom Israel Ltd	Common Stock	M2196U109	4,983	1,332,925	SH		SOLE		1,332,925	0	0
Evonik Industries AG	Common Stock	D2R90Y117	702	19,793	SH		SOLE		19,793	0	0
Fattal Holdings 1998 Ltd	Common Stock	M4148G105	6,150	56,905	SH		SOLE		56,905	0	0
Meituan	Common Stock	G59669104	87,854	2,290,458	SH		SOLE		2,290,458	0	0
SLM Solutions Group AG	Common Stock	D6T690109	22,106	1,064,114	SH		SOLE		1,064,114	0	0
ZhongAn Online P&C Insurance Co Ltd	Common Stock	Y989DF109	114,265	18,941,138	SH		SOLE		18,941,138	0	0
Adyen NV	Common Stock	N3501V104	128,337	57,380	SH		SOLE		57,380	0	0
Atlassian Corp PLC	Common Stock	G06242104	60,114	285,226	SH		SOLE		285,226	0	0
Medtronic PLC	Common Stock	G5960L103	4,701	39,796	SH		SOLE		39,796	0	0
Sapiens International Corp NV	Common Stock	G7T16G103	5,816	182,947	SH		SOLE		182,947	0	0
CRISPR Therapeutics AG	Common Stock	H17182108	1,010,179	8,290,350	SH		SOLE		7,367,516	704,010	218,824
Spotify Technology SA	Common Stock	L8681T102	1,042,681	3,891,325	SH		SOLE		3,510,239	289,115	91,971
Allot Ltd	Common Stock	M0854Q105	6,886	431,153	SH		SOLE		431,153	0	0
AudioCodes Ltd	Common Stock	M15342104	5,121	189,795	SH		SOLE		189,795	0	0
Camtek Ltd/Israel	Common Stock	M20791105	7,711	257,883	SH		SOLE		257,883	0	0
Ceragon Networks Ltd	Common Stock	M22013102	4,378	1,161,214	SH		SOLE		1,161,214	0	0
Check Point Software Technologies Ltd	Common Stock	M22465104	5,372	47,974	SH		SOLE		47,974	0	0
Compugen Ltd	Common Stock	M25722105	123,888	14,422,362	SH		SOLE		14,070,300	219,844	132,218
CyberArk Software Ltd	Common Stock	M2682V108	4,787	37,011	SH		SOLE		37,011	0	0
Evogene Ltd	Common Stock	M4119S104	24,175	4,796,679	SH		SOLE		4,796,679	0	0
Fiverr International Ltd	Common Stock	M4R82T106	5,367	24,713	SH		SOLE		24,713	0	0
Ituran Location and Control Ltd	Common Stock	M6158M104	6,770	318,892	SH		SOLE		318,892	0	0
Nova Measuring Instruments Ltd	Common Stock	M7516K103	6,845	75,210	SH		SOLE		75,210	0	0
Radware Ltd	Common Stock	M81873107	5,706	218,772	SH		SOLE		218,772	0	0
Stratasys Ltd	Common Stock	M85548101	269,885	10,420,260	SH		SOLE		8,139,415	1,527,641	753,204
Taro Pharmaceutical Industries Ltd	Common Stock	M8737E108	5,799	78,627	SH		SOLE		78,627	0	0
Tower Semiconductor Ltd	Common Stock	M87915274	5,522	196,917	SH		SOLE		196,917	0	0
UroGen Pharma Ltd	Common Stock	M96088105	5,686	291,870	SH		SOLE		291,870	0	0
Wix.com Ltd	Common Stock	M98068105	6,733	24,114	SH		SOLE		24,114	0	0
NXP Semiconductors NV	Common Stock	N6596X109	116,862	580,421	SH		SOLE		580,421	0	0
DocuSign Inc	Common Stock	256163106	647,378	3,197,720	SH		SOLE		3,056,146	106,151	35,423
Zscaler Inc	Common Stock	98980G102	107	621	SH		SOLE		621	0	0
GMO internet Inc	Common Stock	J1822R104	23	800	SH		SOLE		800	0	0
Discovery Ltd	Common Stock	S2192Y109	48,849	5,438,981	SH		SOLE		5,438,981	0	0
Inmode Ltd	Common Stock	M5425M103	7,379	101,962	SH		SOLE		101,962	0	0
Perion Network Ltd	Common Stock	M78673114	8,086	451,724	SH		SOLE		451,724	0	0
Silvergate Capital Corp	Common Stock	82837P408	275,720	1,939,369	SH		SOLE		1,939,369	0	0
Meituan	ADR	58533E103	161	2,055	SH		SOLE		2,055	0	0
Z Holdings Corp	Common Stock	J9894K105	71,151	14,293,530	SH		SOLE		14,293,530	0	0
Sea Ltd	ADR	81141R100	707,879	3,171,074	SH		SOLE		2,924,996	188,718	57,360
Z Holdings Corp	ADR	98877X101	567	57,245	SH		SOLE		57,245	0	0
Pure Storage Inc	Common Stock	74624M102	708,402	32,887,736	SH		SOLE		29,671,107	2,638,808	577,821
Synopsys Inc	Common Stock	871607107	381,024	1,537,753	SH		SOLE		1,469,312	45,794	22,647
HUYA Inc	ADR	44852D108	214,054	10,988,392	SH		SOLE		10,020,754	735,617	232,021
RADA Electronic Industries Ltd	Common Stock	M81863124	6,955	579,065	SH		SOLE		579,065	0	0
PagerDuty Inc	Common Stock	69553P100	401,600	9,982,602	SH		SOLE		8,614,212	1,041,802	326,588
Caterpillar Inc	Common Stock	149123101	88,567	381,967	SH		SOLE		381,967	0	0
Arconic Corp	Common Stock	03966V107	3,965	156,152	SH		SOLE		156,152	0	0
Lightspeed POS Inc	Common Stock	53227R106	1,054	16,774	SH		SOLE		16,774	0	0
Adaptive Biotechnologies Corp	Common Stock	00650F109	139,860	3,473,910	SH		SOLE		3,473,910	0	0
10X Genomics Inc	Common Stock	88025U109	634,246	3,504,121	SH		SOLE		3,168,614	263,960	71,547
Crowdstrike Holdings Inc	Common Stock	22788C105	60,981	334,124	SH		SOLE		334,124	0	0
Bitcoin Fund/The	Closed-End Fund	09175G104	12,887	199,331	SH		SOLE		0	0	199,331
Schrodinger Inc/United States	Common Stock	80810D103	195,443	2,561,846	SH		SOLE		2,561,846	0	0
Slack Technologies Inc	Common Stock	83088V102	192	4,735	SH		SOLE		4,735	0	0
TCS Group Holding PLC	GDR	87238U203	77,375	1,334,047	SH		SOLE		1,334,047	0	0
Phreesia Inc	Common Stock	71944F106	66,517	1,276,726	SH		SOLE		1,276,726	0	0
Virgin Galactic Holdings Inc	Common Stock	92766K106	52,919	1,727,671	SH		SOLE		1,727,671	0	0
Workhorse Group Inc	Common Stock	98138J206	55,072	3,999,408	SH		SOLE		3,999,408	0	0
Adyen NV	ADR	00783V104	81,003	1,810,940	SH		SOLE		1,810,940	0	0
Cie Generale des Etablissements Michelin SCA	Common Stock	F61824144	5,408	36,059	SH		SOLE		36,059	0	0
voestalpine AG	Common Stock	A9101Y103	721	17,367	SH		SOLE		17,367	0	0
Yeahka Ltd	Common Stock	G9835C108	87,478	12,712,000	SH		SOLE		12,712,000	0	0
Accolade Inc	Common Stock	00437E102	240,774	5,306,902	SH		SOLE		5,306,902	0	0
Berkeley Lights Inc	Common Stock	084310101	256,976	5,115,992	SH		SOLE		5,115,992	0	0
Vertex Pharmaceuticals Inc	Common Stock	92532F100	369,406	1,719,046	SH		SOLE		1,719,046	0	0
BYD Co Ltd	ADR	05606L100	53,408	1,234,435	SH		SOLE		1,234,435	0	0
Biondvax Pharmaceuticals Ltd	ADR	09073Q105	37	9,778	SH		SOLE		9,778	0	0
Kamada Ltd	Common Stock	M6240T109	5,288	866,366	SH		SOLE		866,366	0	0
BATM Advanced Communications Ltd	Common Stock	M19199112	5,526	4,174,208	SH		SOLE		4,174,208	0	0
Gamida Cell Ltd	Common Stock	M47364100	5,423	670,324	SH		SOLE		670,324	0	0
Gilat Satellite Networks Ltd	Common Stock	M51474118	6,852	655,093	SH		SOLE		655,093	0	0
PolyPid Ltd	Common Stock	M8001Q118	5,292	577,747	SH		SOLE		577,747	0	0
Silicom Ltd	Common Stock	M84116108	6,221	137,871	SH		SOLE		137,871	0	0
Nintendo Co Ltd	ADR	654445303	442,706	6,252,905	SH		SOLE		5,562,959	545,522	144,424
Organovo Holdings Inc	Common Stock	68620A203	5,844	606,221	SH		SOLE		602,693	3,528	0
Surface Oncology Inc	Common Stock	86877M209	31,740	4,069,255	SH		SOLE		4,069,255	0	0
Takeda Pharmaceutical Co Ltd	ADR	874060205	341,775	18,717,144	SH		SOLE		18,717,144	0	0
Niu Technologies	ADR	65481N100	68,264	1,862,592	SH		SOLE		1,862,592	0	0
Thermo Fisher Scientific Inc	Common Stock	883556102	110,349	241,791	SH		SOLE		241,791	0	0
Exact Sciences Corp	Common Stock	30063P105	1,205,607	9,148,635	SH		SOLE		8,404,723	594,597	149,315
Snowflake Inc	Common Stock	833445109	22	98	SH		SOLE		98	0	0
Unity Software Inc	Common Stock	91332U101	812,174	8,096,637	SH		SOLE		7,510,902	424,492	161,243
Beam Therapeutics Inc	Common Stock	07373V105	382,519	4,779,104	SH		SOLE		4,779,104	0	0
Novartis AG	Common Stock	H5820Q150	618,936	7,219,265	SH		SOLE		6,984,729	155,467	79,069
Regeneron Pharmaceuticals Inc	Common Stock	75886F107	576,743	1,218,970	SH		SOLE		1,155,645	60,867	2,458
Repare Therapeutics Inc	Common Stock	760273102	41,695	1,358,589	SH		SOLE		1,358,589	0	0
MarketAxess Holdings Inc	Common Stock	57060D108	16,528	33,195	SH		SOLE		33,195	0	0
Agora Inc	ADR	00851L103	86,283	1,716,390	SH		SOLE		1,716,390	0	0
KE Holdings Inc	ADR	482497104	546,555	9,592,049	SH		SOLE		8,776,600	641,970	173,479
Fastly Inc	Common Stock	31188V100	96,450	1,433,563	SH		SOLE		1,433,563	0	0
Cloudflare Inc	Common Stock	18915M107	66,218	942,466	SH		SOLE		942,466	0	0
Palantir Technologies Inc	Common Stock	69608A108	433,950	18,632,471	SH		SOLE		17,628,771	647,600	356,100
Raven Industries Inc	Common Stock	754212108	53,867	1,405,340	SH		SOLE		1,405,340	0	0
Zoom Video Communications Inc	Common Stock	98980L101	964,624	3,002,347	SH		SOLE		2,784,682	157,985	59,680
Honeywell International Inc	Common Stock	438516106	704	3,245	SH		SOLE		3,245	0	0
Alphabet Inc	Common Stock	02079K305	6	3	SH		SOLE		3	0	0
Roche Holding AG	ADR	771195104	328,770	8,105,763	SH		SOLE		8,105,763	0	0
Sarepta Therapeutics Inc	Common Stock	803607100	138,648	1,860,293	SH		SOLE		1,860,293	0	0
Opendoor Technologies Inc	Common Stock	683712103	246,680	11,641,318	SH		SOLE		11,641,318	0	0
BASE Inc	Common Stock	J0433G101	32,554	2,260,400	SH		SOLE		2,260,400	0	0
Kaspi.KZ JSC	GDR	48581R205	10,776	151,780	SH		SOLE		151,780	0	0
908 Devices Inc	Common Stock	65443P102	52,034	1,072,866	SH		SOLE		1,072,866	0	0
Magna International Inc	Common Stock	559222401	62,254	707,109	SH		SOLE		707,109	0	0
Peloton Interactive Inc	Common Stock	70614W100	113,730	1,011,477	SH		SOLE		1,011,477	0	0
Veeva Systems Inc	Common Stock	922475108	219,052	838,508	SH		SOLE		838,508	0	0
Grayscale Ethereum Trust	Open-End Fund	389638107	11,433	639,069	SH		SOLE		0	639,069	0
Bristol-Myers Squibb Co	Common Stock	110122108	137,618	2,179,919	SH		SOLE		2,179,919	0	0
SPDR S&P 500 ETF Trust	ETP	78462F103	22	55	SH		SOLE		55	0	0
1Life Healthcare Inc	Common Stock	68269G107	42,920	1,098,269	SH		SOLE		1,098,269	0	0
PyroGenesis Canada Inc	Common Stock	74734T104	1,420	211,000	SH		SOLE		211,000	0	0
Arad Ltd	Common Stock	M1492B104	5,688	395,760	SH		SOLE		395,760	0	0
Augwind Energy Tech Storage Ltd	Common Stock	M6058P108	4,505	193,616	SH		SOLE		193,616	0	0
Bet Shemesh Engines Holdings 1997 Ltd	Common Stock	M20119109	5,894	278,364	SH		SOLE		278,364	0	0
Electra Consumer Products 1970 Ltd	Common Stock	M3798N105	6,827	158,105	SH		SOLE		158,105	0	0
E&M Computing Ltd	Common Stock	M4026X105	8,659	1,213,008	SH		SOLE		1,213,008	0	0
Ham-Let Israel-Canada Ltd	Common Stock	M5257K100	6,094	318,886	SH		SOLE		318,886	0	0
Intercure Ltd	Common Stock	M549GJ103	8,376	5,139,550	SH		SOLE		5,139,550	0	0
Itamar Medical Ltd	Common Stock	M61483109	5,167	6,710,537	SH		SOLE		6,710,537	0	0
Magic Software Enterprises Ltd	Common Stock	559166103	5,139	331,141	SH		SOLE		331,141	0	0
Malam - Team Ltd	Common Stock	M87437105	6,201	219,895	SH		SOLE		219,895	0	0
Plasson Industries Ltd	Common Stock	M7933B108	5,755	120,887	SH		SOLE		120,887	0	0
RoboGroup T.E.K Ltd	Common Stock	M20330102	4,615	2,674,171	SH		SOLE		2,674,171	0	0
Desktop Metal Inc	Common Stock	25058X105	15,355	1,030,570	SH		SOLE		1,030,570	0	0
DarioHealth Corp	Common Stock	23725P209	5,231	271,619	SH		SOLE		271,619	0	0
Enlivex Therapeutics Ltd	Common Stock	M4130Y106	5,283	476,414	SH		SOLE		476,414	0	0
Experience Investment Corp	Common Stock	30217C208	30,799	2,744,999	SH		SOLE		2,744,999	0	0
JFrog Ltd	Common Stock	M6191J100	4,040	91,060	SH		SOLE		91,060	0	0
Eastman Kodak Co	Common Stock	277461406	575	73,084	SH		SOLE		73,084	0	0
Kornit Digital Ltd	Common Stock	M6372Q113	6,053	61,070	SH		SOLE		61,070	0	0
Lockheed Martin Corp	Common Stock	539830109	102,261	276,755	SH		SOLE		276,755	0	0
Nano-X Imaging Ltd	Common Stock	M70700105	3,898	94,053	SH		SOLE		94,053	0	0
PACCAR Inc	Common Stock	693718108	293,409	3,157,652	SH		SOLE		2,724,925	344,432	88,295
SolarEdge Technologies Inc	Common Stock	83417M104	5,300	18,439	SH		SOLE		18,439	0	0
Skillz Inc	Common Stock	83067L109	114,473	6,012,260	SH		SOLE		6,012,260	0	0
Teledyne Technologies Inc	Common Stock	879360105	88,925	214,977	SH		SOLE		214,977	0	0
Twitter Inc	Common Stock	90184L102	495,884	7,793,240	SH		SOLE		7,082,389	585,409	125,442
AbbVie Inc	Common Stock	00287Y109	59,858	553,117	SH		SOLE		553,117	0	0
Butterfly Network Inc	Common Stock	124155102	88,969	5,286,325	SH		SOLE		5,286,325	0	0
CM Life Sciences Inc	Common Stock	18978W109	63,008	4,231,546	SH		SOLE		4,231,546	0	0
Signify Health Inc	Common Stock	82671G100	49,567	1,694,034	SH		SOLE		1,694,034	0	0
ARK Innovation ETF	ETP	00214Q104	2,171	18,101	SH		SOLE		18,101	0	0
Ping An Healthcare and Technology Co Ltd	Common Stock	G71139102	50,296	4,010,500	SH		SOLE		4,010,500	0	0
Bill.com Holdings Inc	Common Stock	090043100	24,605	169,108	SH		SOLE		169,108	0	0
DraftKings Inc	Common Stock	26142R104	268,345	4,375,424	SH		SOLE		4,227,724	93,000	54,700
Atlas Crest Investment Corp	Common Stock	049284102	14,668	1,459,498	SH		SOLE		1,459,498	0	0
One	Common Stock	G7000X105	24,385	2,103,928	SH		SOLE		2,103,928	0	0
Vuzix Corp	Common Stock	92921W300	53,017	2,084,017	SH		SOLE		2,084,017	0	0
ARK Genomic Revolution ETF	ETP	00214Q302	953	10,735	SH		SOLE		10,735	0	0
Seer Inc	Common Stock	81578P106	42,431	848,274	SH		SOLE		848,274	0	0
iShares Russell 1000 Growth ETF	ETP	464287614	795	3,270	SH		SOLE		3,270	0	0
Airbus SE	Common Stock	N0280G100	1,013	8,928	SH		SOLE		8,928	0	0
Thales SA	Common Stock	F9156M108	2,512	25,234	SH		SOLE		25,234	0	0
Komatsu Ltd	Common Stock	J35759125	2,880	93,188	SH		SOLE		93,188	0	0
Boeing Co/The	Common Stock	097023105	2,290	8,990	SH		SOLE		8,990	0	0
Garmin Ltd	Common Stock	H2906T109	1,292	9,797	SH		SOLE		9,797	0	0
HEICO Corp	Common Stock	422806109	724	5,756	SH		SOLE		5,756	0	0
L3Harris Technologies Inc	Common Stock	502431109	3,164	15,613	SH		SOLE		15,613	0	0
The 3D Printing ETF	ETP	00214Q500	3,891	100,170	SH		SOLE		100,170	0	0
ROBLOX Corp	Common Stock	771049103	33,509	516,877	SH		SOLE		516,877	0	0
Reinvent Technology Partners	Common Stock	G7483N129	457	45,000	SH		SOLE		45,000	0	0
Jaws Spitfire Acquisition Corp	Common Stock	G50740102	8,164	796,478	SH		SOLE		796,478	0	0
Spirit AeroSystems Holdings Inc	Common Stock	848574109	2,046	42,063	SH		SOLE		42,063	0	0