Realm Therapeutics POS AM Prospectus update (post-effective amendment)

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

The Board of DirectorsRealm Therapeutics plc:

We consent to the use of our report included herein and to the reference to our firm under the heading “Experts” in the prospectus.

/s/ KPMG LLP

Philadelphia, PennsylvaniaAugust 21, 2018