Science 37 (SNCE) Form 3 Science 37 / Holding Co Jaguar II ownership change

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
10/06/2021

3. Issuer Name and Ticker or Trading Symbol
Science 37 Holdings, Inc. [ SNCE ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	17,314,315	D(1)(2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person^*

PHARMACEUTICAL PRODUCT DEVELOPMENT, LLC

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Wildcat Acquisition Holdings (UK) Ltd

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Jaguar Holding Co II

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Jaguar Holding Co I, LLC

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

Eagle Holding Co II, LLC

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

1. Name and Address of Reporting Person^*

PPD, Inc.

(Last) (First) (Middle)

929 NORTH FRONT STREET

(Street)

WILMINGTON NC 28401

(City) (State) (Zip)

Explanation of Responses:

1. These shares of common stock, par value $0.0001 per share, of Science 37 Holdings, Inc. are held of record by Pharmaceutical Product Development, LLC ("Pharma LLC"). Wildcat Acquisition Holdings (UK) Limited ("Wildcat") is the sole member of Pharma LLC; Jaguar Holding Company II ("Jaguar II") is the sole shareholder of Wildcat; Jaguar Holding Company I, LLC ("Jaguar I") is the sole shareholder of Jaguar II; Eagle Holding Company II, LLC ("Eagle II") is the sole member of Jaguar I; and PPD, Inc. is the sole member of Eagle II. By virtue of such relationships, each of the reporting persons may be deemed to have beneficial ownership over such shares of common stock.

2. This report on Form 3 is jointly filed by the reporting persons. Each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein.

Remarks:

	Pharmaceutical Product Development, LLC By: /s/ Julia James, Name: Julia James, Title: EVP, General Counsel and Secretary	10/18/2021
	Wildcat Acquisition Holdings (UK) Limited By: /s/ B. Judd Hartman, Name: B. Judd Hartman, Title: Director	10/18/2021
	Jaguar Holding Company II By: /s/ Julia James, Name: Julia James, Title: General Counsel and Secretary	10/18/2021
	Jaguar Holding Company I, LLC By: Eagle Holding Company II, LLC, By: /s/ B. Judd Harman, Name: B. Judd Hartman, Title: General Counsel and Secretary	10/18/2021
	Eagle Holding Company II, LLC, By: /s/ B. Judd Harman, Name: B. Judd Hartman, Title: General Counsel and Secretary	10/18/2021
	PPD, Inc. By: /s/ Julia James, Name: Julia James, Title: EVP, General Counsel and Secretary	10/18/2021
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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