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Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements on Forms S-3 (Nos. 333-264296) and Forms S-8 (Nos. 333-263536, Nos. 333-254453 and 333-251336) of Sigilon Therapeutics, Inc. of our report dated March 14, 2023 relating to the financial statements, which appears in this Form 10-K.
/s/ PricewaterhouseCoopers LLP
Boston, Massachusetts
March 14, 2023