First Financial 8-K Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549
		Form 8-K
Current Report Pursuant to Section 13 or 15(d)of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported):  November 10,  2010
First Financial Holdings, Inc.
(Exact name of registrant as specified in charter)
Delaware		0-17122		57-0866076
State or other jurisdiction of incorporation		Commission File Number	I.R.S. Employer I.D. number
2440 Mall Drive, Charleston, South Carolina  29406
(Address of principal executive offices)
Registrant's telephone number (including area code):  (843) 529-5933
Not applicable
(Former name or former address, if changed since last report)
[  ]	Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[  ]	Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[  ]	Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[  ]	Pre-commencement communications pursuant to Rule 13e-4c under the Exchange Act (17 CFR 240.13e-4(c))

Section 7 – Regulation FD

Item 7.01 Regulation FD Disclosure

On November 11, 2010, R. Wayne Hall, CEO of First Financial Holdings, Inc. and Blaise B. Bettendorf, CFO of First Financial Holdings, Inc. will present at the Sandler O’Neill + Partners, L.P. East Coast Financial Services Conference.  For more information regarding this matter, see the presentation attached hereto as Exhibit 99.1.  As referenced in the press release dated November 8, 2010, Mr. Hall and Ms. Bettendorf will present at the conference on Thursday, November 11, 2010 at 2:10 p.m. E.S.T.   You may access the live webcast via a link on the Company’s website at www.firstfinancialholdings.com.  Additionally, on November 11, 2010, First Financial&# 8217;s quarterly investor presentation will be available on our website and will remain available through February 10, 2011.  This updated presentation will be used throughout the quarter.

Section 9 -- Financial Statements and Exhibits

Item 9.01 Financial Statements and Exhibits

(d) Exhibits

Exhibit (99.1). Presentation of November 10, 2010.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	FIRST FINANCIAL HOLDINGS, INC
	/s/ Blaise B. Bettendorf
	Blaise B. Bettendorf
	Executive Vice President
	and Chief Financial Officer
Date: November 10, 2010

EXHIBIT INDEX

Exhibit Number	Description
99.1	Presentation of November 10, 2010