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Exhibit 16.1
August 24, 2010
Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549-7561
Dear Sirs/Madams:
We have read Soligenix, Inc.’s statements included under Item 4.01 on its Form 8-K filed on August 20, 2010 and we agree with such statements concerning our firm.
/s/ Amper, Politziner & Mattia, LLP