Vertex Pharmaceuticals (VRTX) 10-K 2006 FY Annual report

Exhibit 10.43

Vertex Pharmaceuticals Non-Employee Board Compensation

Annual Retainer:	$25,000
Board Meeting Fees
In-Person Board Meetings	$2,500
Telephonic Board Meetings	$1,250 (none for meetings called for less than 30 minutes)
Committee Meeting Fees
In-Person on Regular Board Meeting Day	$500
In-Person Meeting held on Day other than regular	$1,000
Board Meeting Day
Telephone Meeting	$375
Committee Chair Compensation
Audit Chair	$20,000 annual retainer
Corporate Governance & Nominating	$20,000 annual retainer
Committee Chair
Management Development & Compensation Committee Chair	$14,000 annual retainer
Equity Grants	Upon first election to the Board, 30,000 options, vesting quarterly over four years; and
	On June 1 of each year in service, 20,000 fully vested options
	On date of Annual Meeting, Chairman of Board, 20,000 fully vested options