Exhibit 8.1
At December 31, 2008 | Country | Percentage of voting share capital held | Principal activity | |
UK | ||||
AstraZeneca UK Limited | England | 100 | (1) | Research and development, manufacturing, marketing |
AstraZeneca Reinsurance Limited | England | 100 | Insurance and reinsurance underwriting | |
AstraZeneca Treasury Limited | England | 100 | Treasury | |
Continental Europe | ||||
NV AstraZeneca SA | Belgium | 100 | Manufacturing, marketing | |
AstraZeneca Dunkerque Production SCS | France | 100 | Manufacturing | |
AstraZeneca SAS | France | 100 | Research, manufacturing, marketing | |
AstraZeneca GmbH | Germany | 100 | Development, manufacturing, marketing | |
AstraZeneca Holding GmbH | Germany | 100 | Manufacturing, marketing | |
AstraZeneca SpA | Italy | 100 | Manufacturing, marketing | |
AstraZeneca Farmaceutica Spain SA | Spain | 100 | Manufacturing, marketing | |
AstraZeneca AB | Sweden | 100 | Research and development, manufacturing, marketing | |
AstraZeneca BV | The Netherlands | 100 | Marketing | |
The Americas | ||||
AstraZeneca Canada Inc. | Canada | 100 | Research, manufacturing, marketing | |
IPR Pharmaceuticals Inc. | Puerto Rico | 100 | Development, manufacturing, marketing | |
AstraZeneca LP | US | 99 | Research and development, manufacturing, marketing | |
AstraZeneca Pharmaceuticals LP | US | 100 | Research and development, manufacturing, marketing | |
Zeneca Holdings Inc. | US | 100 | Manufacturing, marketing | |
MedImmune, Inc. | US | 100 | Research and development, manufacturing, marketing | |
Asia, Africa & Australasia | ||||
AstraZeneca Pty Limited | Australia | 100 | Development, manufacturing, marketing | |
AstraZeneca KK | Japan | 80 | Manufacturing, marketing |
1) Shares held directly.
The companies and other entities listed above are those whose results or financial position principally affected the figures shown in the Group Financial Statements. A full list of subsidiaries, joint ventures and associates will be annexed to the Company’s next annual return filed with the Registrar of Companies. The country of registration or incorporation is stated alongside each company. The accounting year ends of subsidiaries and associates are 31 December, except for Aptium Oncology, Inc. which, owing to local conditions and to avoid undue delay in the preparation of the Financial Statements, is 30 November. AstraZeneca operates through 290 subsidiaries worldwide. The Group Financial Statements consolidate the Financial Statements of the Company and its subsidiaries at 31 December 2007. Products are manufactured in 20 countries worldwide and are sold in over 100 countries. |