Exhibit 32.2
CERTIFICATION PURSUANT TO
18 U.S.C. SECTION 1350,
AS ADOPTED PURSUANT TO
SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002
In connection with the Annual Report of OPKO Health, Inc. (the “Company”) on Form 10-K/A for the year ended December 31, 2009 (the “Report”), and pursuant to pursuant to 18 U.S.C. §1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, I, Rao Uppaluri, Chief Financial Officer of the Company, certify that to the best of my knowledge:
| | (1) | | The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and |
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| | (2) | | The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company. |
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| | /s/ Rao Uppaluri | |
| | Rao Uppaluri | |
| Chief Financial Officer | |
| November 10, 2010 | |
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