| Document And Entity Information | Feb. 27, 2025 |
| Document Information [Line Items] | |
| Entity, Registrant Name | OPKO Health, Inc. |
| Document, Type | 8-K |
| Document, Period End Date | Feb. 27, 2025 |
| Entity, Incorporation, State or Country Code | DE |
| Entity, File Number | 001-33528 |
| Entity, Tax Identification Number | 75-2402409 |
| Entity, Address, Address Line One | 4400 Biscayne Blvd. |
| Entity, Address, City or Town | Miami |
| Entity, Address, State or Province | FL |
| Entity, Address, Postal Zip Code | 33137 |
| City Area Code | 305 |
| Local Phone Number | 575-4100 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | OPK |
| Security Exchange Name | NASDAQ |
| Entity, Emerging Growth Company | false |
| Amendment Flag | false |
| Entity, Central Index Key | 0000944809 |
