36 patents
Page 2 of 2
Utility
Methods for Treating Pulmonary Non-tuberculous Mycobacterial Infections
29 Jul 21
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle.
Gina EAGLE, Renu GUPTA
Filed: 24 Sep 20
Utility
Certain (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES for Treating Anca Associated Vasculitides
24 Jun 21
Keith DIPETRILLO, Carlos FERNANDEZ, Jimin ZHANG
Filed: 25 Jan 21
Utility
Sustained Release of Antiinfectives
29 Apr 21
Provided are lipid antiinfective formulations substantially free of anionic lipids with a lipid to antiinfective ratio is about 1:1 to about 4:1, and a mean average diameter of less than about 1 μm.
Lawrence T. BONI, Brian S. MILLER, Vladimir MALININ, Xingong LI
Filed: 30 Oct 20
Utility
Methods for the Manufacture of Liposomal Drug Formulations
22 Apr 21
Provided herein is a method for the large-scale manufacture of liposomal drug formulations containing an aminoglycoside such as amikacin having advantageous lipid/drag characteristics.
Robert WORSHAM
Filed: 2 May 19
Utility
Methods for Continuous Manufacture of Liposomal Drug Products
21 Jan 21
Provided herein are methods for making liposomal API formulations via continuous in-line diafiltration processes.
Robert WORSHAM
Filed: 29 Mar 19
Utility
Lipid-based Compositions of Antiinfectives for Treating Pulmonary Infections and Methods of Use Thereof
16 Dec 20
A system for treating or providing prophylaxus against a pulmonary infection is disclosed comprising: a) a pharmaceutical formulation comprising a mixture of free antiinfective and antiinfective encapsulated in a lipid-based composition, and b) an inhalation delivery device.
Jeff WEERS
Filed: 16 Jan 20
Utility
Certain (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES for Treating Anca Associated Vasculitides
16 Dec 20
Keith DIPETRILLO, Carlos FERNANDEZ, Jimin ZHANG
Filed: 5 Feb 19
Utility
Glycopeptide Derivative Compounds and Uses Thereof
25 Nov 20
Provided herein are methods and compositions for the treatment of Gram positive bacterial infections.
Ryan HECKLER, Donna KONICEK, Adam PLAUNT, Vladimir MALININ, Walter PERKINS
Filed: 21 May 18
Utility
Methods for Treating Pulmonary Non-tuberculous Mycobacterial Infections
4 Nov 20
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle.
Gina EAGLE, Renu GUPTA
Filed: 14 Jul 20
Utility
Dry Powder Compositions of Treprostinil Prodrugs and Methods of Use Thereof
28 Oct 20
Ju DU, Adam PLAUNT, Vladimir MALININ
Filed: 27 Apr 20
Utility
Methods for Treating Pulmonary Non-tuberculous Mycobacterial Infections
26 Aug 20
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle.
Gina EAGLE, Renu GUPTA
Filed: 30 Jan 20
Utility
Certain (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES for Treating Bronchiectasis
10 Jun 20
Hans Roland LONN, Stephen CONNOLLY, Steven SWALLOW, Reinilde HEYRMAN, Eugene SULLIVAN, Carlos FERNANDEZ
Filed: 14 Jul 19
Utility
Lipo-glycopeptide Cleavable Derivatives and Uses Thereof
20 May 20
The present invention provides certain lipo-glycopeptide cleavable derivatives and methods for using the same for the treatment of bacterial infections, for example, pulmonary bacterial infections.
Ryan HECKLER, Donna KONICEK, Adam PLAUNT, Vladimir MALININ, Walter PERKINS
Filed: 21 May 18
Utility
Prostacyclin Compounds, Compositions and Methods of Use Thereof
11 Mar 20
Prostacyclin compounds and compositions comprising the same are provided herein.
Vladimir MALININ, Walter PERKINS, Franziska LEIFER, Donna KONICEK, Zhili LI, Adam PLAUNT
Filed: 14 Nov 19
Utility
Methods for Treating Pulmonary Non-tuberculous Mycobacterial Infections
8 Jan 20
Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle.
Gina Eagle, Renu Gupta
Filed: 17 Jul 19
Utility
Methods of Manufacturing Treprostinil and Treprostinil Derivative Prodrugs
6 Nov 19
Methods for making prodrugs of trepreostinil and treprostinil derivatives are provided.
Vladimir Malinin, Walter Perkins, Franziska Leifer, Donna M. Konicek, Zhili Li, Adam Plaunt
Filed: 20 May 19