54 patents
Page 2 of 3
Utility
GHB Dosing
25 Nov 21
Provided herein are methods of administering GHB formulations for the treatment of narcolepsy and other conditions.
Franck SKOBIERANDA
Filed: 6 Aug 21
Utility
Euglobulin-based Method for Determining the Biological Activity of Defibrotide
25 Nov 21
It is disclosed a method for determining the biological activity of defibrotide, which comprises the steps of: a) bringing into contact defibrotide, mammalian euglobulin and a substrate specific for the plasmin which, by reaction with the plasmin, provides a measurable product; and b) measuring the amount of product formed at successive times, to thereby determine the biological activity of the defibrotide.
Terenzio IGNONI, Vijay KUMAR, Khalid ISLAM
Filed: 6 Aug 21
Utility
Controlled Release Dosage Forms for High Dose, Water Soluble and Hygroscopic Drug Substances
11 Nov 21
Controlled release dosage forms are described herein.
Clark ALLPHIN, James PFEIFFER
Filed: 20 Jul 21
Utility
High Concentration Formulations
4 Nov 21
Low-viscosity, high concentration nucleic acid compositions that can be administered by multiple parenteral routes may allow for less frequent dosing than nucleic acid products currently on the market.
Mariana DIMITROVA, William J. BENNETT, Qi WANG
Filed: 16 Jul 21
Utility
Sensitive Drug Distribution Systems and Methods
23 Sep 21
A computerized system distributes a plurality of different prescription drugs under exclusive control of an exclusive central pharmacy.
Sherice ReneƩ Mills, Jerry Yu
Filed: 23 Mar 20
Utility
Methods of Providing Solriamfetol Therapy to Subjects with Impaired Renal Function
23 Sep 21
The invention relates to methods for decreasing adverse effects associated with solriamfetol ([R]-2-amino-3-phenylpropylcarbamate) therapy in subjects with impaired renal function.
Katayoun Zomorodi
Filed: 14 Jan 21
Utility
Controlled Release Dosage Forms for High Dose, Water Soluble and Hygroscopic Drug Substances
12 Aug 21
Controlled release dosage forms are described herein.
Clark ALLPHIN, James PFEIFFER
Filed: 7 Apr 21
Utility
Method of Administration of Gamma Hydroxybutyrate with Monocarboxylate Transporters
15 Jul 21
One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient.
Mark ELLER
Filed: 29 Mar 21
Utility
Formulations of (R)-2-AMINO-3-PHENYLPROPYL Carbamate
8 Jul 21
The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
Clark Patrick Allphin, Edwin Gerard Walsh
Filed: 21 Jan 21
Utility
Methods and Compositions for Treating Excessive Sleepiness
8 Jul 21
The present invention relates to carbamoyl phenylalaninol compounds and methods of using the same to treat disorders.
Lawrence Patrick Carter, Yuan Lu, Katayoun Zomorodi
Filed: 25 Mar 21
Utility
GHB Dosing
24 Jun 21
Provided herein are methods of administering GHB formulations for the treatment of narcolepsy and other conditions.
Franck SKOBIERANDA
Filed: 22 Dec 20
Utility
Defibrotide for the Prevention and Treatment of Cytokine Release Syndrome and Neurotoxicity Associated with Immunodepletion
24 Jun 21
The present disclosure provides method of preventing, lessening the effects, or treating cytokine release syndrome (CRS) or related disorders, and/or neurotoxicity associated with immunotherapy comprising administering defibrotide.
Sarah McMAHON, Yasuhiro OKI
Filed: 12 Apr 19
Utility
Method of Administration of Gamma Hydroxybutyrate with Monocarboxylate Transporters
6 May 21
One embodiment of the present invention is to improve the safety and efficacy of the administration of GHB or a salt thereof to a patient.
Mark ELLER
Filed: 10 Nov 20
Utility
Gamma-hydroxybutyrate Compositions and Their Use for the Treatment of Disorders
29 Apr 21
Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB).
Clark P. Allphin, Gunjan Junnarkar, Roman Skowronski, Cuiping Chen, Katayoun Zomorodi, Mark Eller, Philip McGarrigle
Filed: 22 Dec 20
Utility
Immediate Release Formulations and Dosage Forms of Gamma-hydroxybutyrate
1 Apr 21
The present invention provides a solid immediate release dosage form adapted for oral administration of GHB.
Andrea ROURKE, Maura Patricia MURPHY, James Frederick PFEIFFER, Clark Patrick ALLPHIN, Alya Khan McGINLAY
Filed: 9 Oct 20
Utility
Carbamoyl Phenylalaninol Analogs and Uses Thereof
1 Apr 21
The present invention relates to carbamoyl phenylalaninol analogs and methods of using the same to treat disorders.
Fionn Hurley
Filed: 31 Jul 18
Utility
Treatment for Obesity
18 Mar 21
The present invention relates to a method for treating or preventing obesity in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
Moise A. Khayrallah, Gary Bream, Stephen E. Butts
Filed: 22 Sep 20
Utility
Compositions comprising (R)-2-amino-3-phenylpropyl carbamate and uses thereof
25 Feb 21
The present invention relates to a newly identified solvate form of (R)-2-amino-3-phenylpropyl carbamate (APC) hydrochloride, a method of preparing APC hydrochloride, and methods of using the same to treat disorders.
Fionn Hurley
Filed: 6 Nov 20
Utility
Defibrotide for Use In Prophylaxis And/or Treatment of Graft Versus Host Disease (GVHD)
25 Feb 21
Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) in humans is disclosed, preferably in hematopoietic stem cell transplantation (HSCT), more preferably allogeneic hematopoietic stem cell transplantation.
Massimo IACOBELLI
Filed: 29 Jul 20
Utility
Sensitive Drug Distribution Systems and Methods
21 Jan 21
A drug distribution system and method utilizes a central pharmacy and database to track all prescriptions for a sensitive drug.
Prasheel Vashdev Lillaney, Sherice ReneƩ Mills, Gary Joseph Appio
Filed: 2 Oct 20