45 patents
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Utility
Chimeric Cells Comprising Dendritic Cells and Endothelial Cells Resembling Tumor Endothelium
29 Sep 22
Disclosed are means, methods and compositions of matter useful for induction of immunological responses towards tumor endothelial cells.
Thomas E. ICHIM, Timothy G. DIXON, Feng LIN, Famela RAMOS, James VELTMEYER
Filed: 18 Mar 22
Utility
Pluripotent Stem Cell Derived Dendritic Cells and Engineered Dendritic Cells for Cancer Immunotherapy
22 Sep 22
Disclosed are populations of dendritic cells generated from stem cells capable of inducing immunity towards cancer.
Thomas E. ICHIM, Famela RAMOS, James VELTMEYER, Timothy G. DIXON
Filed: 16 Mar 22
Utility
Therapeutic Monocytes for Prevention of Suicidal Ideation
8 Sep 22
The invention discloses compositions of matter, protocols, and therapeutic means for treatment of suicidal ideations and/or suppression of suicidal attempts.
Thomas E. Ichim, Timothy G. Dixon, Famela Ramos, Kalina O'Connor, James Veltmeyer
Filed: 4 Mar 22
Utility
Ex Vivo Generation of Immunocytes Recognizing Brother of the Regulator of Imprinted Sites (Boris) Expressing Cancer Stem Cells
25 Aug 22
Disclosed are means, methods and compositions of matter useful for induction of immunity towards cancer stem cells by providing a dendritic cell, wherein said dendritic cells express BORIS and/or peptides derived from BORIS, wherein said dendritic cell is cultured in the presence of one or more immunocytes.
Thomas E. Ichim, Timothy G. Dixon, Feng LIN, Famela Ramos, James Veltmeyer
Filed: 22 Feb 22
Utility
Stimulation of Natural Kill Cell Memory by Administration of Dendritic Cells
11 Aug 22
Disclosed are means, methods and compositions of matter useful for induction of natural killer cell memory by administration of dendritic cells and/or exosomes thereof.
Thomas E. ICHIM, Timothy G. DIXON, James VELTMEYER, Famela RAMOS
Filed: 8 Feb 22
Utility
Stimulation of Dendritic Cell Activity by Homotaurine and Analogues Thereof
28 Jul 22
Disclosed are means, methods, and compositions of matter useful for enhancement of dendritic cell activity.
Thomas Ichim, Timothy G. Dixon, James Veltmeyer, Famela Ramos
Filed: 26 Jan 22
Utility
Immunotherapy for Opioid Addiction
23 Jun 22
Disclosed are means, methods and compositions of matter useful for reduction of brain inflammation and prevention of opioid addiction and/or tolerance.
Thomas Ichim, Timothy G. Dixon, Famela Ramos, Wais Kaihani, James Veltmeyer, Kalina O'Connor
Filed: 20 Dec 21
Utility
Nutraceutical Reduction Prevention and/or Reversion of Multiple Sclerosis
23 Jun 22
Disclosed are compositions of matter, protocols, and treatment means for preventing and/or reversing multiple sclerosis in a mammal.
Thomas Ichim, J. Christopher Mizer, Timothy G. Dixon, Famela Ramos, Kalina O'Connor
Filed: 19 Oct 21
Utility
Treatment of Major Depressive Disorder and Suicidal Ideations Through Stimulation of Hippocampal Neurogenesis Utilizing Plant-based Approaches
9 Jun 22
Disclosed are means and methods of treating major depressive disorder and/or other disorders that predispose to suicide by administration of nutraceutical means, wherein said nutraceuticals are administered at a frequency and/or concentration sufficient to induce proliferation of endogenous neural progenitor cells.
Thomas Ichim, Timothy G. Dixon, James Veltmeyer, Kalina O'Connor
Filed: 8 Dec 21
Utility
Stimulation of NK Cell Activity by QuadraMune Alone and together with Metformin
26 May 22
Disclosed are means, compounds, and compositions of matter useful for stimulation of natural killer cell activity.
Thomas Ichim, Timothy G. Dixon, Famela Ramos, Wais Kaihani
Filed: 23 Nov 21
Utility
Prevention of Pathological Coagulation in COVID-19 and other Inflammatory Conditions
12 May 22
The invention is directed to the utilization of pterostilbene, and/or nigella sativa extract, and/or sulforaphane, and/or Epigallocatechin gallate (EGCG) alone or in combination, for the prevention of pathological coagulation.
Thomas E. Ichim, James Veltmeyer, Timothy G. Dixon
Filed: 13 Sep 21
Utility
Protection and Regeneration of Neurological Function by Using Stem Cells
28 Apr 22
Disclosed are therapeutic compounds, protocols, and compositions of matter useful for treatment of neurological conditions.
Thomas E. Ichim, Timothy G. Dixon, Amit N. Patel, Famela Ramos, Kalina O'Connor
Filed: 27 Oct 21
Utility
Augmentation of Natural Killer Cell Activity and Induction of Cytotoxic Immunity Using Leukocyte Lysate Activated Allogeneic Dendritic Cells: Stemvacs
31 Mar 22
Stimulation of immunity would be beneficial in various chronic conditions such as viral infections and neoplasia.
Thomas E. ICHIM, Timothy G. DIXON, James VELTMEYER
Filed: 30 Jun 21
Utility
Personalized Immunotherapies for Reduction of Brain Inflammation and Suicide Prevention
24 Mar 22
Disclosed are means, methods and compositions of matter useful for reduction of brain inflammation and prevention of suicidal ideations and suicidal attempts.
Thomas E. Ichim, Timothy G. Dixon, Famela Ramos, Kalina O'Connor
Filed: 24 Sep 20
Utility
Nutraceuticals for the prevention, inhibition, and treatment of SARS-CoV-2 and associated COVID-19
8 Mar 22
Disclosed herein are methods of treating or preventing complications associated with a SARS-CoV-2 infection, comprising: administration of a combination comprising: a) Green Tea and/or extract thereof; b) Blueberry and/or extract thereof; c) Nigella sativa and/or extract thereof; and d) broccoli and/or extract thereof in an amount and frequency sufficient to treat or prevent complications associated with said SARS-CoV-2 infection.
Thomas E Ichim, Timothy G Dixon
Filed: 4 May 20
Utility
Upregulation of Therapeutic T Regulatory Cells and Suppression of Suicidal Ideations in Response to Inflammation by Administration of Nutraceutical Compositions Alone or Combined with Minocycline
3 Mar 22
Disclosed are compositions of matter, treatments and protocols useful for induction of T regulatory cells in response to inflammation, as well as inhibition of suicidal ideations and/or neuroinflammation.
Thomas E. Ichim, Timothy G. Dixon, Kalina O'Connor
Filed: 30 Aug 21
Utility
Prevention of Neuroinflammation associated Memory Loss Using Nutraceutical Compositions
10 Feb 22
Disclosed are means, methods, and therapeutic compositions for prevention of memory loss during situations of neuroinflammation.
Thomas E. Ichim, Famela Ramos, James Veltmeyer, Timothy G. Dixon
Filed: 5 Aug 21
Utility
Neuroprotection and Neuroregeneration by Pterostilbene and Compositions Thereof
3 Feb 22
Disclosed are means, compositions of matter, and protocols useful for neuroprotection and neuroregeneration.
Thomas E. ICHIM, Timothy G. DIXON, James VELTMEYER
Filed: 28 Jul 21
Utility
Additive And/or Synergistic Combinations of Metformin with Nutraceuticals for the Prevention, Inhibition and Treatment of SARS-COV-2 and Associated COVID-19
27 Jan 22
Disclosed are compositions of matter, treatments and protocols useful for prevention of SARS-CoV-2 infection, as well as inhibition of viral propagation and acceleration of viral cure.
Thomas E. Ichim, James Veltmeyer, Timothy G. Dixon
Filed: 22 Jul 21
Utility
Nutraceuticals for suppressing indolamine 2,3 deoxygenase
25 Jan 22
Disclosed are compositions of matter, treatments and protocols useful for reduction of expression and/or activity of indolamine 2,3 deoxygenase (IDO).
Thomas E. Ichim, Timothy G. Dixon, James Veltmeyer
Filed: 23 Oct 20