111 patents
Page 4 of 6
Utility
Mutant 4-hydroxyphenylacetate 3-hydroxylases and uses thereof
27 Apr 21
The present invention relates to genetically modified enzymes obtained by rational design of the active site binding pocket of the prototypic enzyme 4-hydroxyphenylacetate 3-hydroxylase (4HPA3H) for hydroxylating a 4-hydroxyphenyl compound to yield a 3,4-dihydroxyphenyl compound and to biotechnological methods including in vivo and in vitro methods using said enzymes or catalytically active fragments thereof.
Ludger A. Wessjohann, Susann Herrmann, Martin Dippe, Torsten Geissler, Katrin Geissler, Jakob Peter Ley
Filed: 30 Sep 16
Utility
Medicament
6 Apr 21
The present invention belongs to the fields of pharmaceuticals and cosmetics, and concerns on the one hand a medicament for the inhibition of and refers also on the cosmetic, non-therapeutic use for the treatment of hyperpigmentation, particularly induced by sun light radiation, preferably induced by visible light radiation.
Marielle Le Maire, Imke Meyer, William Johncock
Filed: 21 Mar 16
Utility
yeje3eusnyes9swhv5u2in3qxnrhmdm2pu2omm3lsxvt8
9 Mar 21
Suggested is a method for identifying fragrance compounds with low environmental impact and high degree of sustainability encompassing the following steps: (a) providing a fragrance compound or a fragrance composition of interest; (b) calculating scores for each of the following parameters (b1) biodegradability; (b2) biodiversity; (b3) carbon dioxide impact; (b4) process safety with regard to ecological toxicity; (b5) process safety with regard to human toxicity; (b6) land use; (b7) renewability; (b8) traceability; (b9) waste generation; and (b10) water consumption and/or pollution, (c) summing up all scores and calculate the average product sustainability score (PSC); and (d) proceed with those candidates showing a PSC of at least 70.
Pasqual Jahns, Lena Müller, Axel Schöning, Helmut Frieden
Filed: 4 Feb 16
Utility
rjvbny8shb3ubjtcqczsognk6pi9vnk7x10gxvmh7onl3s73go28tu
2 Mar 21
Sven Siegel, Arnold Machinek, Bernd Hölscher
Filed: 5 May 16
Utility
ujcvrtsc3jxgw5nd8qh312hvnc79llyyuf0hri1mrey7 069n1
16 Feb 21
Bernd Hölscher, Johannes Panten
Filed: 19 Jun 17
Utility
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16 Feb 21
Bernd Hölscher, Marc Mansfeld, Tobias Wagner
Filed: 21 Mar 17
Utility
f0o60lg69uctnczodi33ezrboi
9 Feb 21
Oskar Koch, Marcus Rudolf Götz
Filed: 6 Nov 18
Utility
xb3ihnaaplfwehv6idqvlq4832c3vt3ert 20g0xy2sar9z3at1k
28 Dec 20
Bernd Hölscher, Marc Mansfeld, Tobias Wagner, Julia Amos
Filed: 14 Feb 16
Utility
60zwf4a6lmmwba zvolftmcmkmrn
28 Dec 20
The present invention primarily concerns the use of 2,3,6-trimethylcyclohexanol as a fragrance and/or flavoring.
Bernd Hölscher, Manfred Meier
Filed: 26 Nov 17
Utility
b0p0lphnjre7x6f991yrqpsqus0z6b3mwkt
28 Dec 20
The invention relates to a method for producing scent capsules with improved surfactant stability, comprising the following steps: (a) providing a scent composition containing at least one scent which has at least one functional group that can form an acid group by means of oxidation or hydrolysis, and (b) encapsulating the scent mixture, characterised in that a scent composition is used that has an acid value of no more than 5 mg KOH/g immediately before encapsulation.
Patrick Ott, Daniela Gregor, Kolja Behrens, Wiebke Begemann
Filed: 28 Feb 16
Utility
3fvj63wyw1w wcwiteopjwugthfjdt9yph41jkgx6x34ipso77es661
21 Dec 20
Katharina Reichelt, Jakob Peter Ley, Petra Hoffmann-Lücke, Maria Blings, Susanne Paetz, Thomas Riess
Filed: 10 Mar 20
Utility
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7 Dec 20
Gabriele Vielhaber
Filed: 14 Dec 15
Utility
yb6w1i6zi38bvsg4vydqhmrd9r6cc07jyb398g827fm
7 Dec 20
Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of purple coneflower pressed juice, sclareolide, ginger root C02 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.
Jean Krutmann, Imke Meyer, William Johncock, Gerhard Schmaus, Marielle le Maire, Martina Herrmann
Filed: 24 May 16
Utility
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16 Nov 20
Daniela Busse, Heike Conrad, Hanns Hatt
Filed: 15 Jun 15
Utility
kaoeq2rzznxgutr4hi4bwzowjot iy
16 Nov 20
The invention relates to a method for producing microcapsules, comprising the following steps: (a) providing a first aqueous preparation containing at least one prepolymer; (b) providing a second non-aqueous preparation containing the active substance to be encapsulated; (c) mixing the aqueous and the non-aqueous phases in the presence of at least one emulsifier and/or stabilizer in order to form an emulsion; (d) polymerizing the at least one prepolymer contained in the emulsion from step (c) in order to obtain a dispersion of microcapsules that enclose the active substance; (e) hardening and cross-linking the microcapsules obtained in step (d); and optionally (f) removing the microcapsules from the dispersion and drying the microcapsules, the method being characterized in that the emulsion is formed in the presence of at least one 1,2-diol in step (c).
Benjamin Rost, Ralf Bertram, Daniela Gregor, Jan Peter Ebbecke, Sabine Lange
Filed: 21 Apr 17
Utility
h8pl6z1rrhvxhkjtmtsqky387vg9k9vd1a4bzv 0km83rvnb7di52t
9 Nov 20
The present invention belongs to the area of body odour modelling.
Marco Singer, Keith McDermott, Marcela Olalde-Castillo, George Preti, Charles Wysocki, Katherine Ashley Prigge
Filed: 21 Oct 15
Utility
jlnmplr2z018s4d4ipj46kx6mkabznidvql9tjdh351d88g5bb965uu4ot
26 Oct 20
The invention relates to substance mixtures which contain (a) sodium carboxymethyl cellulose and (b) at least one bitter principle selected from the group consisting of xanthines, phenolic glycosides, flavanoid glycosides, hydrolysable or non-hydrolysable tannins, flavones and the glycosides thereof, caffeic acid and the esters thereof, terpenoid bitter principles, catechin, epicatechin, epigallocatechin, gallocatechin, gallocatechin-3-gallate, leucine, isoleucine, valine, tryptophan and phenylalanine, protein hydrolysates, peptides and metal salts and their mixtures, and optionally (c) dextrins, with the proviso that the components (a) and (b) are in the weight ratio of from 1:1 to 1:1,000.
Sabine Widder, Kathrin Langer, Gerhard Krammer, Olga Pauli, Cornelia Homner
Filed: 2 Jun 15
Utility
j05m97bar0fzc3fjyalsjkm5 64fqdiopn75s04mjnprmba9eq0o
5 Oct 20
Suggested is a device for assessing the sillage of fragrance materials, comprising or consisting of the following parts: (i) an evaluation tube (1) that is open on both ends; (ii) a ventilation system (2); (iii) at least two lockable sniffing ports (3a, 3b . . . ); (iv) a sample port (4); (v) a sample plate (5) and optionally (vi) a sample holder (6) whereby (a) said evaluation tube (1) is aligned horizontally and equipped with said at least two sniffing ports (3) and said sample port (4); (b) the front opening of said evaluation tube (1) is equipped with said ventilation system (2); (c) at least one sniffing port (3a) is located in the front section and at least one sniffing port (2b) is located in the rear section of said evaluation tube (3); (d) said sample port (4) is located within the front section of said evaluation tube (1); and (e) said sample port (4) has a diameter allowing to introduce either the sample plate (5) or the sample holder (6) into the evaluation tube (1).
Matthias Luetkenhaus, Aurélien Saint-Paul, Marco Singer, Sophie Bensamou, Céline Carrasco
Filed: 30 Apr 16
Utility
6ld436fsp6yqrj9xcyqq8fkgpeompatc7qnnzbkyjlx
21 Sep 20
Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice, ginger root CO2 extract or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.
Jean Krutmann, Imke Meyer, William Johncock, Gerhard Schmaus, Marielle le Maire, Martina Herrmann
Filed: 23 May 16
Utility
cj35lpk6dqn oq619l96movm1ozl977n0z6iy
21 Sep 20
Suggested is a cosmetic composition comprising an anti-pollution agent selected from the group consisting of ginger root C02 extract, E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one, sclareolide, purple coneflower pressed juice or mixtures thereof, in a working amount sufficient for (a) reducing or preventing air pollution induced gene expression, and/or (b) reducing or preventing a gene expression induced or inducible by polycyclic aromatic hydrocarbons, and/or (c) reducing or preventing air pollution-induced or air pollution-inducible skin damage.
Jean Krutmann, Imke Meyer, William Johncock, Gerhard Schmaus, Marielle le Maire
Filed: 24 May 16