34 patents
Utility
Method for preparation of chlorinated s-propylthiobarbituric acid
22 Jun 20
The invention discloses a method for preparation of 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine by conversion of 5-nitro-2-propylthiopyrimidine-4,6-diol with phosgene in the presence of DMF.
Michael Bersier, Paul Hanselmann, Candid Stoffel
Filed: 15 Jul 18
Utility
Customizable facility
22 Jun 20
A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.
Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominik Imbolden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri
Filed: 24 Jul 17
Utility
Method and system for providing buffer solutions
1 Jun 20
A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site.
Tristan Wilkins
Filed: 1 Aug 17
Utility
Method for Preparation of Alkylated or Fluoro, Chloro and Fluorochloro Alkylated Compounds by Heterogeneous Cobalt Catalysis
20 May 20
The invention discloses a method for preparation of alkylated, fluoro alkylated, chloro alkylated and fluorochloro alkylated compounds by a heterogeneous Co-catalysed alkylation or fluoro, chloro and fluorochloro alkylation with alkyl halides, fluoro alkyl halides, chloro alkyl halides or fluorochloro alkyl halides respectively.
Christoph Taeschler, Florencio Zaragoza Doerwald, Stefan Ellinger, Matthias Beller, Helfried Neumann, Florian Fischer
Filed: 25 Jul 18
Utility
Modulation of lipid metabolism for protein production
18 May 20
The present disclosure features methods and compositions for modulating lipid metabolism to achieve improved production and quality of recombinant products, such as next generation biologics.
James Budge, Christopher Mark Smales, Tanya Jeane Knight, Robert Young
Filed: 2 May 17
Utility
System and Method for Cleaning Membrane Filters In-line In a Water Purification System
13 May 20
A process and system for cleaning semipermeable membranes is described that is particularly well suited for cleaning membranes contained in a water purification system, such as a reverse osmosis process.
Michael Mietzner
Filed: 7 Nov 19
Utility
Method for Preparation of Difluoromethylornithine
13 May 20
The invention discloses a method for preparation of protected difluoromethylornithine by a difluoromethylation of dibenzaldimine ornithine ester using CHF3 and LiHMDS (lithium bis(trimethylsilyl)amide), which can be converted to a salt of unprotected difluoromethylornithine by a subsequent deprotection under acidic conditions in the presence of water.
Bernhard GUTMANN, Michael BERSIER, Paul HANSELMANN, Christian Oliver KAPPE, Manuel KOECKINGER, Christopher HONE
Filed: 23 Sep 18
Utility
Activated disinfectant hydrogen peroxide compositions
11 May 20
Activated hydrogen peroxide disinfecting compositions are provided especially for low-foaming applications.
Deqing Lei, Philip Gerdon Sweeny
Filed: 16 Sep 15
Utility
Method and Composition for Increasing the Bioavailability of Carnitine
29 Apr 20
A method and composition for improving the health of a mammal, such as by increasing the bioavailability of L-carnitine to the mammal.
Aouatef Bellamine
Filed: 27 Oct 19
Utility
Solid Bar Shampoo
29 Apr 20
The present invention provides a shampoo bar composition, at least 60 w/w % of one or more surfactants, wherein at least one or more of the surfactant comprises a polyglyceryl ester.
Adam Griffiths, Louise Reay
Filed: 27 Oct 19
Utility
Hair Cleansing and Conditioning Composition
29 Apr 20
The present invention provides a hair cleansing conditioner composition containing a) 0.01 w/w %-20 w/w % of a cationic surfactant; b) 0.01 w/w %-20 w/w % of a polyglyceryl ester; and c) 0.01 w/w %-15 w/w %, of at least one fatty alcohol.
Louise Reay, Victor Low, Jordan Todorov Petkov, Elias Pambou
Filed: 27 Oct 19
Utility
Disinfectant composition having residual biocidal properties
27 Apr 20
A composition having biocidal properties is disclosed.
Xiao Jiang, Joseph Kimler, Milady Brutofsky
Filed: 5 Dec 18
Utility
Color Stable Preservative Composition
1 Apr 20
Provided herein is a disclosure that blending a dicarboxylic acid with a ketonic acid, used as a preservative in a end-use formulation, such as a personal care product, can mitigate the discoloration of the end-use formulation which is caused by an elevated pH in the end-use formulation or in end-use formulations which have been exposed to elevated temperature.
Angela Sangirardi, Mayumi Furukawa
Filed: 25 Sep 19
Utility
Recombinant host cell for expressing proteins of interest
16 Mar 20
The present invention is in the field of recombinant biotechnology, in particular in the field of protein expression.
Brigitte Gasser, Diethard Mattanovich, Markus Buchetics
Filed: 15 Apr 15
Utility
Filter Moving Device
26 Feb 20
A filter moving device is disclosed that is designed to lift and move a filter cartridge stack comprised of individual filter cartridges.
Danny Sugianto
Filed: 6 Nov 17
Utility
High-Concentrate Flowable Liquid Anionic Surfactant Composition
26 Feb 20
Described is a high-concentrate flowable liquid anionic surfactant composition containing an alkyl ether sulfate and a viscosity modifier(s).
Adam Stephen Griffiths, Jordan Todorov Petkov
Filed: 25 Aug 19
Utility
Dried Rehydratable Composition
26 Feb 20
The present disclosure provides a dried rehydratable composition, containing a gelling agent, and a pharmaceutical or cosmetic active ingredient; Further described is a method of rehydrating a dried rehydratable composition, which may be used as a skin benefiting material and may be formulated as a cream, gel, hydrogel, gel or hydrogel patch, mask (including face-mask), lotion, leave-on or rinse-off cosmetic or pharmaceutical product.
Daniel Thorn Leeson, Khat Kevin Lou, Jordan Todorov Petkov
Filed: 25 Aug 19
Utility
Process for Creating Reference Data for Predicting Concentrations of Quality Attributes
26 Feb 20
A process and system for efficiently producing reference data that can be fed into a predictive model for predicting quality attribute concentrations in cell culture processes.
Brandon John Downey, John Michael Schmitt
Filed: 20 Aug 19
Utility
Quaternary ammonium acid compounds and compositions for disinfection, sanitization, and cleaning
24 Feb 20
A disinfecting composition comprising a quaternary ammonium acid compound and hydrogen peroxide is disclosed.
Marcus Bentley, Andrew Colurciello, Danuel Brown
Filed: 9 Jan 19
Utility
System and method for regulating cell culture based production of biologics
24 Feb 20
The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant.
Rex Polley, Matthew Sarcopski, Robert Horton, Thomas Ellis, Paul Pease, John Chapin
Filed: 13 Oct 16