12 patents
Utility
Method for preparation of chlorinated s-propylthiobarbituric acid
22 Jun 20
The invention discloses a method for preparation of 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine by conversion of 5-nitro-2-propylthiopyrimidine-4,6-diol with phosgene in the presence of DMF.
Michael Bersier, Paul Hanselmann, Candid Stoffel
Filed: 15 Jul 18
Utility
Customizable facility
22 Jun 20
A campus for fabricating at least one pharmaceutical product has one or more customizable facilities each configured to manufacture the at least one pharmaceutical product, a media/buffer plant, and a utility building connected by a utility line to the media/buffer plant and/or the one or more customizable facilities to provide at least one first utility to the media/buffer plant and/or the one or more customizable facilities via the utility line.
Leander Biffiger, Sandra Carbonneau, Andre Collioud, Jonathan Fortin, Dominik Imbolden, Torsten Schmidt, Stefan Stoffel, Diego Studer, Christoph Vogel, Stefan Widmer, Tristan Wilkins, Lesley Wood, Alexander Zahiri
Filed: 24 Jul 17
Utility
Method and system for providing buffer solutions
1 Jun 20
A method for delivering a processing solution includes providing a concentrated processing solution in a bioprocess container, the concentrated processing solution being produced at a first site.
Tristan Wilkins
Filed: 1 Aug 17
Utility
Modulation of lipid metabolism for protein production
18 May 20
The present disclosure features methods and compositions for modulating lipid metabolism to achieve improved production and quality of recombinant products, such as next generation biologics.
James Budge, Christopher Mark Smales, Tanya Jeane Knight, Robert Young
Filed: 2 May 17
Utility
Activated disinfectant hydrogen peroxide compositions
11 May 20
Activated hydrogen peroxide disinfecting compositions are provided especially for low-foaming applications.
Deqing Lei, Philip Gerdon Sweeny
Filed: 16 Sep 15
Utility
Disinfectant composition having residual biocidal properties
27 Apr 20
A composition having biocidal properties is disclosed.
Xiao Jiang, Joseph Kimler, Milady Brutofsky
Filed: 5 Dec 18
Utility
Recombinant host cell for expressing proteins of interest
16 Mar 20
The present invention is in the field of recombinant biotechnology, in particular in the field of protein expression.
Brigitte Gasser, Diethard Mattanovich, Markus Buchetics
Filed: 15 Apr 15
Utility
Quaternary ammonium acid compounds and compositions for disinfection, sanitization, and cleaning
24 Feb 20
A disinfecting composition comprising a quaternary ammonium acid compound and hydrogen peroxide is disclosed.
Marcus Bentley, Andrew Colurciello, Danuel Brown
Filed: 9 Jan 19
Utility
System and method for regulating cell culture based production of biologics
24 Feb 20
The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant.
Rex Polley, Matthew Sarcopski, Robert Horton, Thomas Ellis, Paul Pease, John Chapin
Filed: 13 Oct 16
Utility
Liquid laundry detergent composition for clothing
7 Oct 19
Mutsumi Nakanishi, Kazuhiko Sakata
Filed: 5 Feb 15
Utility
Rupture disks for bioreactors and methods of using same
7 Oct 19
A rupture disk includes a body including an internal wall extending from a first end of the body to a second end of the body.
Michael Mietzner
Filed: 7 Dec 17
Utility
Constitiutive promoter
30 Sep 19
The invention relates to an isolated nucleic acid sequence comprising a promoter, which is a native sequence of Pichia pastoris comprising the nucleic acid sequence of pCS1 of SEQ ID 1, or a functionally active variant thereof which is a size variant, a mutant or hybrid of SEQ ID 1, or a combination thereof, expression constructs and recombinant host cells comprising the promoter, and a method of producing a protein of interest under the control of the promoter.
Diethard Mattanovich, Brigitte Gasser, Roland Prielhofer
Filed: 17 Dec 13
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