13 patents
Utility
Tyrosine Derivatives and Compositions Comprising Them
6 Oct 22
Compositions and kits comprising a tyrosine hydroxylase inhibitor and an anticancer agent that is chemically bonded to, or physically associated with, the tyrosine hydroxylase inhibitor are provided.
Steven HOFFMAN
Filed: 23 Jun 22
Utility
D-metyrosine Compositions and Methods for Preparing Same
26 May 22
John ZUCARO
Filed: 18 Mar 20
Utility
Crystalline Forms of Metyrosine
6 Jan 22
The disclosure provides crystalline compositions comprising D-metyrosine and L-metyrosine, pharmaceutical formulation comprising one or more crystalline composition described herein and a pharmaceutically acceptable excipient, methods for treating cancer in a patient in need thereof, the method comprising administering to the patient one or more composition described herein, and methods for preparing the compositions described herein.
John Zucaro
Filed: 1 Jul 21
Utility
Pharmaceutical Compositions And Methods
16 Dec 21
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 30 Aug 21
Utility
Pharmaceutical Compositions and Methods
9 Dec 21
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 2 Jul 21
Utility
Methods of Treating SARS-COV-2 Infections
18 Nov 21
The disclosure is directed to methods of using TUDCA, or a pharmaceutically acceptable salt thereof, or a derivative thereof, for the treatment of SARS-CoV-2 infections.
Steven Hoffman, John Rothman
Filed: 6 Jan 21
Utility
Tumor Reduction Formulations and Methods of Use Thereof
9 Sep 21
The invention relates to tumor reducing compositions and methods thereof.
Steven Hoffman, John Rothman
Filed: 2 Jul 19
Utility
Compositions And Methods For Modulating Cancer
22 Jul 21
The present inventions provide compositions and methods for modulating cancer using a tyrosine derivative.
Steven Hoffman
Filed: 15 Jan 21
Utility
Pharmaceutical Compositions and Methods
10 Jun 21
Methods of treating cancer or reducing tumor size by contacting a patient's cancer cells or tumor with an effective amount of a pharmaceutical composition as further defined herein.
Steven Hoffman, John Rothman
Filed: 9 Dec 20
Utility
Transdermal Formulations
30 Dec 20
The present disclosure is directed to transdermal compositions comprising isothiocyanates or isocyanates.
Steven HOFFMAN
Filed: 13 Sep 18
Utility
Compositions and Methods for Treating Cancer
18 Nov 20
The present invention provides methods for treating cancer.
Steven Hoffman
Filed: 13 May 20
Utility
Pharmaceutical Compositions for the Treatment of Cancer
4 Nov 20
The present disclosure provides methods, compositions, and kits for treating cancer using a combination of L-rhamnose and a leucine aminopeptidase inhibitor.
Steven HOFFMAN
Filed: 16 Jul 20
Utility
Pharmaceutical Compositions and Methods
8 Apr 20
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 10 Dec 19
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