8 patents
Utility
Compositions and methods for treating cancer
27 Dec 22
Disclosed are methods for treating cancer by reduction of glycogen stores and administering tyrosine derivatives.
Steven Hoffman
Filed: 14 May 20
Utility
Pharmaceutical compositions and methods
31 Aug 21
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 10 Apr 20
Utility
High-speed centrifugal mixing devices and methods of use
24 Aug 21
A centrifugal mixing device can include a shaft assembly that is operably coupled to a motor such that the motor rotates the shaft assembly about a first axis.
Steven Hoffman
Filed: 28 Jun 17
Utility
Tyrosine derivatives and compositions comprising them
13 Jul 21
Provided herein are methods comprising providing a tyrosine derivative and a solid particulate material (and, optionally, melanin) and applying force to said tyrosine derivative and said solid particulate material for a time and under conditions effective to impregnate at least one of said tyrosine derivative and said solid particulate material with the other of said tyrosine derivative and said solid particulate material.
Steven Hoffman
Filed: 6 Mar 17
Utility
Pharmaceutical compositions and methods
6 Jul 21
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 11 Dec 19
Utility
Methods of treating SARS-COV-2 infections
2 Feb 21
The disclosure is directed to methods of using TUDCA, or a pharmaceutically acceptable salt thereof, or a derivative thereof, for the treatment of SARS-CoV-2 infections.
Steven Hoffman, John Rothman
Filed: 6 Jul 20
Utility
Pharmaceutical compositions and methods
11 May 20
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 22 May 19
Utility
Pharmaceutical compositions and methods
16 Dec 19
Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are provided.
Steven Hoffman
Filed: 10 Mar 19
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