2 patents
Utility
Assays for nucleosome remodeling activity
8 Nov 22
The invention relates to assays for nucleosome remodeling activity using functionalized recombinant mononucleosomes.
Michael-Christopher Keogh, Martis William Cowles, Matthew Fruge Whelihan
Filed: 18 May 18
Utility
Quantification of nucleosome modifications using chemically-defined recombinant nucleosomes
28 Sep 20
The invention relates to the use of recombinant/semi-synthetic nucleosomes carrying histone and/or DNA modifications as a reference standard for quantification of covalently modified (on the histone proteins or wrapping DNA), variant, or mutant nucleosomes (collectively “modified nucleosomes” or “nucleosome modifications”) from a biological sample.
Martis William Cowles, Matthew F. Whelihan, Andrea L. Johnstone, Michael-Christopher Koegh, Zu-Wen Sun, Nathan W. Hall, Matthew R. Marunde
Filed: 7 Nov 19
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