26 patents
Utility
Therapeutic microvesicles of probiotic bacteria
2 Jan 24
A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria.
Stefan Roos, Wolfgang Kunze, John Bienenstock
Filed: 17 Apr 20
Utility
Gos Pre-conditioning L. Reuteri and Gos In Final Formulation
21 Dec 23
The invention herein relates generally to enhancing the survival and activity of probiotic Lactobacillus reuteri strains in mammals by pre-conditioning L. reuteri with GOS during cultivation and to a surprisingly high symbiotic effect of such a pre-conditioned probiotic L. reuteri strain when administered together with GOS further added in the composition.
Stefan ROOS, Marie Noëlle HORCAJADA, Nicolas BONNET, Magalie SABATIER, Bertrand BOURQUI, Guénolée Eliane Marie PRIOULT, Florac DE BRUYN
Filed: 11 Mar 22
Utility
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26 Oct 23
The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.
Stefan Roos
Filed: 29 Jun 23
Utility
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22 Aug 23
The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.
Stefan Roos
Filed: 14 Feb 22
Utility
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3 Aug 23
The present invention relates to the field of topical compositions comprising probiotic bacteria showing improved properties for storage and stability.
Christoffer LUNDQVIST, Eile BUTLER, Jonas FAIJERSON SÄLJÖ
Filed: 30 Jun 21
Utility
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3 Aug 23
The invention herein discloses histamine-producing bacterial strains for use in the prophylaxis, inhibition, treatment or reducing a risk of relapse of cancer, including colorectal cancer.
James Versalovic, Bo Mollstam, Chunxu Gao, Bhanu Priya Ganesh
Filed: 1 Dec 22
Utility
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20 Jul 23
The present invention relates to a probiotic Lactobacillus reuteri strain obtained by growing the bacteria in a medium comprising galacto-oligosaccharides (GOS), so called pre-conditioning.
Stefan ROOS, Marie Noëlle HORCAJADA, Nicolas BONNET, Magalie SABATIER, Bertrand BOURQUI, Guénolée Eliane Marie PRIOULT, Florac DE BRUYN
Filed: 11 Mar 22
Utility
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18 Jul 23
The invention concerns Lactobacillus reuteri for use in the prevention or treatment of microbiota dysbiosis, in particular, decreased levels of Actinobacteria and increased levels of Proteobacteria, in young mammals and in the prevention or treatment of disorders associated therewith.
Clara Lucia Garcia-Rodenas, Bernard Berger, Catherine Ngom-Bru, Melissa Lepage, Tara Neville
Filed: 20 May 22
Utility
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14 Mar 23
The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX).
Stefan Roos, Yuying Liu, Baokun He, Jon Marc Rhoads
Filed: 26 May 17
Utility
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23 Feb 23
The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of adenosine, for use in the production of adenosine in a subject.
Stefan Roos
Filed: 24 Jul 19
Utility
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10 Nov 22
The invention relates to selection of bacterial strain for use in treating serotonin deficiency and/or a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan.
Estelle Grasset, Muhammed Khan, Bo Möllstam, Stefan Roos
Filed: 6 Nov 20
Utility
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3 Nov 22
The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject.
Stefan Roos, Bo Möllstam
Filed: 24 Jul 19
Utility
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20 Oct 22
The invention concerns Lactobacillus reuteri for use in the prevention or treatment of microbiota dysbiosis, in particular, decreased levels of Actinobacteria and increased levels of Proteobacteria, in young mammals and in the prevention or treatment of disorders associated therewith.
Clara Lucia Garcia-Rodenas, Bernard Berger, Catherine Ngom-Bru, Melissa Lepage, Tara Neville
Filed: 20 May 22
Utility
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29 Sep 22
A method is provided for evaluating agents for the treatment of different intestinal motility disorders, using distinct methodological parts related to musculature and nerves of the GI tract which communicate with the brain.
Eamonn Connolly, Wolfgang Kunze, John Bienenstock
Filed: 15 Jun 22
Utility
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2 Jun 22
The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.
Stefan Roos
Filed: 14 Feb 22
Utility
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29 Mar 22
The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.
Stefan Roos
Filed: 27 Mar 18
Utility
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13 Jan 22
Bacterial strains useful in prophylaxis, inhibition and/or treatment of an allergy in a mammal are selected by screening bacterial strains for capability of producing diacylglycerol kinase (DagK).
James Versalovic, Bo Mollstam, Bhanu Priya Ganesh
Filed: 31 Aug 21
Utility
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5 Oct 21
Bacterial strains useful in prophylaxis, inhibition and/or treatment of an allergy in a mammal are selected by screening bacterial strains for capability of producing diacylglycerol kinase (DagK).
James Versalovic, Bo Mollstam, Bhanu Priya Ganesh
Filed: 8 May 17
Utility
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27 May 21
A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria.
Stefan Roos, Wolfgang Kunze, John Bienenstock
Filed: 17 Apr 20
Utility
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4 Mar 21
The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX).
Stefan Roos, Yuying Liu, Baokun He, Jon Marc Rhoads
Filed: 26 May 17