BioGaia AB (publ) (BIOGY) USPTO patentsUtility grant

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Therapeutic microvesicles of probiotic bacteria

2 Jan 24

A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria.

Stefan Roos, Wolfgang Kunze, John Bienenstock

Filed: 17 Apr 20

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Lactic acid bacteria, methods and uses thereof

22 Aug 23

The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.

Stefan Roos

Filed: 14 Feb 22

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18 Jul 23

The invention concerns Lactobacillus reuteri for use in the prevention or treatment of microbiota dysbiosis, in particular, decreased levels of Actinobacteria and increased levels of Proteobacteria, in young mammals and in the prevention or treatment of disorders associated therewith.

Clara Lucia Garcia-Rodenas, Bernard Berger, Catherine Ngom-Bru, Melissa Lepage, Tara Neville

Filed: 20 May 22

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14 Mar 23

The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX).

Stefan Roos, Yuying Liu, Baokun He, Jon Marc Rhoads

Filed: 26 May 17

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29 Mar 22

The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine.

Stefan Roos

Filed: 27 Mar 18

Utility

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5 Oct 21

Bacterial strains useful in prophylaxis, inhibition and/or treatment of an allergy in a mammal are selected by screening bacterial strains for capability of producing diacylglycerol kinase (DagK).

James Versalovic, Bo Mollstam, Bhanu Priya Ganesh

Filed: 8 May 17

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26 Jan 21

A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals.

James Versalovic, Carissa Michelle Thomas, Eamonn Connolly

Filed: 23 May 18

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18 May 20

The present embodiments relate to selection of agents effective in reducing or preventing gastrointestinal pain in a subject.

Eamonn Conolly, Wolfgang Kunze, John Bienenstock

Filed: 15 May 18

Utility

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20 Jan 20

The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method.

Eamonn Connolly, Robert Allen Britton, Laura Rae McCabe

Filed: 22 Jan 19