154 patents
Page 7 of 8
Utility
Amplification of Cell-free Dna Using Nested PCR
17 Jun 20
Methods for non-invasive prenatal paternity testing are disclosed herein.
Allison Ryan, Styrmir Sigurjonsson, Milena Banjevic, George Gemelos, Matthew Hill, Johan Baner, Matthew Rabinowitz, Zachary Demko
Filed: 19 Feb 20
Utility
Methods for Non-invasive Prenatal Ploidy Calling
17 Jun 20
The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father.
Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
Filed: 26 Feb 20
Utility
System and Method for Cleaning Noisy Genetic Data and Determining Chromosome Copy Number
17 Jun 20
Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available.
Matthew RABINOWITZ, Milena BANJEVIC, Zachary DEMKO, David JOHNSON, Dusan KIJACIC, Dimitri PETROV, Joshua SWEETKIND-SINGER, Jing XU
Filed: 26 Feb 20
Utility
Methods for Non-invasive Prenatal Ploidy Calling
10 Jun 20
The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father.
Matthew RABINOWITZ, George GEMELOS, Milena BANJEVIC, Allison RYAN, Zachary DEMKO, Matthew HILL, Bernhard ZIMMERMANN, Johan BANER
Filed: 19 Feb 20
Utility
System and Method for Cleaning Noisy Genetic Data from Target Individuals Using Genetic Data from Genetically Related Individuals
3 Jun 20
A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed.
Matthew Rabinowitz, Milena Banjevic, Zachary Demko, David Johnson
Filed: 20 Jan 20
Utility
Methods for Simultaneous Amplification of Target Loci
20 May 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua BABIARZ, Tudor Pompiliu CONSTANTIN, Lane A. EUBANK, George GEMELOS, Matthew Micah HILL, Huseyin Eser KIRKIZLAR, Matthew RABINOWITZ, Onur SAKARYA, Styrmir SIGURJONSSON, Bernhard ZIMMERMANN
Filed: 29 Jan 20
Utility
Methods for simultaneous amplification of target loci
18 May 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua Babiarz, Tudor Pompiliu Constantin, Lane A. Eubank, George Gemelos, Matthew Micah Hill, Huseyin Eser Kirkizlar, Matthew Rabinowitz, Onur Sakarya, Styrmir Sigurjonsson, Bernhard Zimmermann
Filed: 13 Mar 19
Utility
System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
18 May 20
A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed.
Matthew Rabinowitz, Milena Banjevic, Zachary Demko, David Johnson
Filed: 29 Apr 19
Utility
Methods for Simultaneous Amplification of Target Loci
13 May 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua BABIARZ, Tudor Pompiliu CONSTANTIN, Lane A. EUBANK, George GEMELOS, Matthew Micah HILL, Huseyin Eser KIRKIZLAR, Matthew RABINOWITZ, Onur SAKARYA, Styrmir SIGURJONSSON, Bernhard ZIMMERMANN
Filed: 20 Jan 20
Utility
Methods for Simultaneous Amplification of Target Loci
6 May 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua BABIARZ, Tudor Pompiliu CONSTANTIN, Lane A. EUBANK, George GEMELOS, Matthew Micah HILL, Huseyin Eser KIRKIZLAR, Matthew RABINOWITZ, Onur SAKARYA, Styrmir SIGURJONSSON, Bernhard ZIMMERMANN
Filed: 14 Jan 20
Utility
Methods for Simultaneous Amplification of Target Loci
22 Apr 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua BABIARZ, Tudor Pompiliu CONSTANTIN, Lane A. EUBANK, George GEMELOS, Matthew Micah HILL, Huseyin Eser KIRKIZLAR, Matthew RABINOWITZ, Onur SAKARYA, Styrmir SIGURJONSSON, Bernhard ZIMMERMANN
Filed: 5 Jan 20
Utility
Systems and Methods for Detection of Aneuploidy
22 Apr 20
Provided herein are improved methods for detecting aneuploidy in a sample.
Styrmir SIGURJONSSON, Naresh VANKAYALAPATI, Allison RYAN, Zachary DEMKO, Milena BANJEVIC
Filed: 6 Nov 19
Utility
Methods for simultaneous amplifications of target loci
23 Mar 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Bernhard Zimmermann, Matthew Hill, Philippe Lacroute, Michael Dodd, Alexander Wong
Filed: 29 Apr 19
Utility
Methods for simultaneous amplification of target loci
23 Mar 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Bernhard Zimmermann, Matthew Hill, Philippe Lacroute, Michael Dodd, Alexander Wong
Filed: 13 May 19
Utility
Methods for simultaneous amplification of target loci
23 Mar 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua Babiarz, Tudor Pompiliu Constantin, Lane A. Eubank, George Gemelos, Matthew Micah Hill, Huseyin Eser Kirkizlar, Matthew Rabinowitz, Onur Sakarya, Styrmir Sigurjonsson, Bernhard Zimmermann
Filed: 26 Feb 19
Utility
System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
23 Mar 20
A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed.
Matthew Rabinowitz, Milena Banjevic, Zachary Demko, David Johnson
Filed: 13 May 19
Utility
Amplification of cell-free DNA using nested PCR
16 Mar 20
Methods for non-invasive prenatal paternity testing are disclosed herein.
Allison Ryan, Styrmir Sigurjonsson, Milena Banjevic, George Gemelos, Matthew Hill, Johan Baner, Matthew Rabinowitz, Zachary Demko
Filed: 29 Apr 19
Utility
Compositions and methods for identifying nucleic acid molecules
2 Mar 20
The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs).
Bernhard Zimmermann, Ryan Swenerton, Matthew Rabinowitz, Styrmir Sigurjonsson, George Gemelos, Apratim Ganguly, Himanshu Sethi
Filed: 25 Sep 17
Utility
Cell free DNA diagnostic testing standards
2 Mar 20
Embodiments of the invention include methods and compositions for producing standards for noninvasive prenatal genetic diagnostics and for the detection and monitoring of cancer.
Joshua Babiarz, Bernhard Zimmermann, Tudor Pompiliu Constantin
Filed: 13 Jan 16
Utility
Methods for simultaneous amplification of target loci
10 Feb 20
The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods.
Joshua Babiarz, Tudor Pompiliu Constantin, Lane A. Eubank, George Gemelos, Matthew Micah Hill, Huseyin Eser Kirkizlar, Matthew Rabinowitz, Onur Sakarya, Styrmir Sigurjonsson, Bernhard Zimmermann
Filed: 29 Apr 19