97 patents
Utility
Methods of Penning Micro-objects Using Positive Dielectrophoresis
23 Mar 23
Methods of selectively positioning a micro-object in a microfluidic device are described in this application.
Volker L.S. Kurz, John A. Tenney, Long Van Le
Filed: 17 Jun 22
Utility
Methods of Amplifying Paired Transcript Sequences from Single Cells
16 Mar 23
The disclosure provides methods for amplification of paired transcript sequences from a single cell, such as, but not limited to alpha and beta T cell receptor (TCR) sequences from a single T cell.
Duane Smith, Jason M. McEwen
Filed: 12 Sep 22
Utility
Lateral/vertical transistor structures and process of making and using same
7 Mar 23
A microfluidic device can include a base an outer surface of which forms one or more enclosures for containing a fluidic medium.
Eric D. Hobbs, Justin K. Valley
Filed: 5 Oct 20
Utility
Microfluidic devices having isolation pens and methods of testing biological micro-objects with same
31 Jan 23
A microfluidic device can comprise at least one swept region that is fluidically connected to unswept regions.
Mark P. White, Eric D. Hobbs, J. Tanner Nevill, Daniele Malleo, Steven W. Short
Filed: 14 Nov 19
Utility
In-situ Generated Microfluidic Assay Structures, Related Kits, and Methods of Use Thereof
26 Jan 23
In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described.
Kristin G. BEAUMONT, Peter J. BEEMILLER, Volker L.S. KURZ, Gregory G. LAVIEU, Xiaohua WANG, Aathavan KARUNAKARAN
Filed: 8 Sep 22
Utility
Systems for Operating Microfluidic Devices
22 Dec 22
Systems for operating a microfluidic device are described.
Angel Navas Angeles, Johannes Paul Sluis, John A. Tenney, Yogesh Khemchandra Dhande, Patrick N. Ingram, Erin Chia-wei Hsi, Christopher C. Shing, John Junyeon Kim, Keith J. Breinlinger, Raziel Solomon Alon
Filed: 25 Apr 22
Utility
Micro-Fluidic Devices for Assaying Biological Activity
8 Dec 22
Biological activity in holding pens in a micro-fluidic device can be assayed by placing in the holding pens capture objects that bind a particular material of interest produced by the biological activity.
Kevin T. Chapman, Daniele Malleo, J. Tanner Nevill, Steven W. Short, Mark P. White, M. Jimena Loureiro
Filed: 24 Mar 22
Utility
Systems and methods for analyses of biological samples
6 Dec 22
Disclosed are methods, systems, and articles of manufacture for performing a process on biological samples.
Darshan Thaker, Keith J. Breinlinger, Vincent Haw Tien Pai, Christoph Andreas Neyer, Thomas M. Vetterli, Hayley M. Bennett, Elisabeth Marie Walczak, Alexander Gerald Olson, Wesley Arthur Zink, John A. Tenney, Oleksandr Tokmakov, Igor Fastnacht, Yuriy Nicheporuk, Andriy Koval, Khrystyna Andres, Alona Kostenko
Filed: 19 May 21
Utility
Capturing Specific Nucleic Acid Materials from Individual Biological Cells In a Micro-fluidic Device
1 Dec 22
Individual biological cells can be selected in a micro-fluidic device and moved into isolation pens in the device.
Kevin T. Chapman, Eric D. Hobbs, Steven W. Short, Mark P. White, Daniele Malleo
Filed: 15 Mar 22
Utility
Microfluidic Cell Culture
10 Nov 22
Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof.
Randall D. LOWE, JR., Kristin G. BEAUMONT, Aathavan KARUNAKARAN, Natalie C. MARKS, Jason M. MCEWEN, Mark P. WHITE, J. Tanner NEVILL, Gang F. WANG, Andrew W. MCFARLAND, Daniele Malleo, Keith J. BREINLINGER, Xiao GUAN, Kevin T. CHAPMAN
Filed: 12 May 22
Utility
Well plate incubator
8 Nov 22
Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed.
Russell A. Newstrom, Andrew W. McFarland, Darcy K. Kelly-Greene, J. Tanner Nevill, Gang F. Wang
Filed: 9 Aug 19
Design
Display screen with graphical user interface
1 Nov 22
Pavan Ramkumar, Michael J. Stone, Keith J. Breinlinger
Filed: 17 Jun 21
Design
Processing instrument
1 Nov 22
Raziel Solomon Alon, Angel Navas Angeles, Ken Huynh, Christopher C. Shing
Filed: 12 Aug 20
Design
Processing instrument
1 Nov 22
Raziel Solomon Alon, Angel Navas Angeles, Ken Huynh, Christopher C. Shing, David Aaron Weisbach
Filed: 12 Aug 20
Design
Processing instrument
1 Nov 22
Raziel Solomon Alon, Angel Navas Angeles, Ken Huynh, Christopher C. Shing, David Aaron Weisbach
Filed: 12 Aug 20
Utility
Systems, Apparatuses, and Methods for Cellular Therapeutics Manufacture
13 Oct 22
Cartridges for manufacturing a population of cells suitable for formulation as a cellular therapeutic are disclosed herein, along with systems and instruments for operating the cartridges and performing methods to generate the population of cells suitable for formulation as a cellular therapeutic.
Andrew W. McFarland, Peter J. Beemiller, Guido K. Stadler, Alexander J. Mastroianni, Joshua J. Cardiel Rivera, Darcy K. Kelly-Greene, Jonathan Cloud Dragon Hubbard, Natalie C. Marks, Long Van Le, Ke-Chih Lin
Filed: 12 Jan 22
Utility
In situ-generated microfluidic assay structures, related kits, and methods of use thereof
27 Sep 22
In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described.
Kristin G. Beaumont, Peter J. Beemiller, Volker L. S. Kurz, Gregory G. Lavieu, Xiaohua Wang, Aathavan Karunakaran
Filed: 22 Jun 20
Utility
Well-plate incubator
6 Sep 22
Incubators are disclosed which include an enclosure with an internal chamber configured to support a cell culture plate and provide an environment suitable for maintaining and/or culturing biological cells.
Darcy K. Kelly-Greene, Russell A. Newstrom, Andrew W. McFarland, J. Tanner Nevill, Gang F. Wang
Filed: 31 May 19
Utility
Methods, Systems and Kits for In-pen Assays
11 Aug 22
Methods, systems and kits are described herein for detecting the results of an assay.
Troy A. LIONBERGER, Matthew E. FOWLER, Phillip J. M. ELMS, Kevin D. LOUTHERBACK, Randall D. LOWE, JR., Jian GONG, J. Tanner NEVILL, Gang F. WANG, Gregory G. LAVIEU, John A. TENNEY, Aathavan KARUNAKARAN, Anupam SINGHAL, I-Jong LIN
Filed: 23 Nov 21
Utility
Light sequencing and patterns for dielectrophoretic transport
5 Jul 22
Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells.
Troy A. Lionberger, Brandon R. Bruhn, John A. Tenney, Eric D. Hobbs
Filed: 5 Jun 20