8 patents
Utility
Reusable Initiators for Synthesizing Nucleic Acids
20 Jul 23
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
J. William Efcavitch, Kim F. Albizati, Natasha Paul, Sanjay Agarwalla
Filed: 11 Jul 22
Utility
Reusable Initiators for Synthesizing Nucleic Acids
6 Apr 23
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
J. William Efcavitch, Matthew T. Holden
Filed: 16 May 22
Utility
Methods and Apparatus for Synthesizing Nucleic Acids
4 Nov 21
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using enzymes and specially designed nucleotide analogs.
J. William Efcavitch, Suhaib Siddiqi
Filed: 12 Jul 21
Utility
Modified Template-independent Enzymes for Polydeoxynucleotide Synthesis
14 Jan 21
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
Julie L. Tubbs, Prem Sinha, Boguslaw Stec, Christopher Wilson, J. William Efcavitch, Deanne W. Sammond
Filed: 3 Jun 20
Utility
Reusable Initiators for Synthesizing Nucleic Acids
9 Dec 20
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
Sanjay Agarwalla
Filed: 5 Apr 20
Utility
Modified Template-independent Enzymes for Polydeoxynucleotide Synthesis
17 Jun 20
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
J. William Efcavitch, Julie L. Tubbs, Prem Sinha, Boguslaw Stec
Filed: 26 Aug 18
Utility
Modified Template-independent Enzymes for Polydeoxynucleotide Synthesis
17 Jun 20
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
J. William Efcavitch, Julie L. Tubbs, Prem Sinha, Boguslaw Stec
Filed: 18 Oct 18
Utility
Homopolymer Encoded Nucleic Acid Memory
13 Nov 19
Nucleic acid memory strands encoding digital data using a sequence of homopolymer tracts of repeated nucleotides provides a cheaper and faster alternative to conventional digital DNA storage techniques.
J. William Efcavitch, Sanjay Agarwalla, Kim Albizati, Alan W. Grubbs, Matthew T. Holden, Patrycja A. Hopkins, Jay K. Singh
Filed: 23 Apr 19
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