8 patents
Utility
Homopolymer encoded nucleic acid memory
28 Mar 23
Nucleic acid memory strands encoding digital data using a sequence of homopolymer tracts of repeated nucleotides provides a cheaper and faster alternative to conventional digital DNA storage techniques.
J. William Efcavitch, Sanjay Agarwalla, Kim Albizati, Alan W. Grubbs, Matthew T. Holden, Patrycja A. Hopkins, Jay K. Singh
Filed: 24 Apr 19
Utility
Modified template-independent enzymes for polydeoxynucleotide synthesis
19 Jul 22
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
Julie L. Tubbs, Prem Sinha, Boguslaw Stec, Christopher Wilson, J. William Efcavitch, Deanne W. Sammond
Filed: 3 Jun 20
Utility
Reusable initiators for synthesizing nucleic acids
12 Jul 22
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
J. William Efcavitch, Kim Albizati, Natasha Paul, Sanjay Agarwalla
Filed: 6 Apr 20
Utility
Reusable initiators for synthesizing nucleic acids
17 May 22
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
J. William Efcavitch, Matthew T. Holden
Filed: 29 Jan 19
Utility
Homopolymer encoded nucleic acid memory
16 Nov 21
Nucleic acid memory strands encoding digital data using a sequence of homopolymer tracts of repeated nucleotides provides a cheaper and faster alternative to conventional digital DNA storage techniques.
J. William Efcavitch, Matthew T. Holden
Filed: 21 Aug 18
Utility
Modified template-independent enzymes for polydeoxynucleotide synthesis
14 Sep 20
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
J. William Efcavitch, Julie L. Tubbs, Prem Sinha, Boguslaw Stec
Filed: 18 Oct 18
Utility
Modified template-independent enzymes for polydeoxynucleotide synthesis
31 Aug 20
The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3′-O-blocking moieties to a nucleic acid initiator, without the use of a template.
J. William Efcavitch, Julie L. Tubbs, Prem Sinha, Boguslaw Stec
Filed: 26 Aug 18
Utility
Reusable initiators for synthesizing nucleic acids
15 Jun 20
The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support.
J. William Efcavitch
Filed: 17 Aug 15
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