17 patents
Utility
Therapeutic Agent for COVID-19
7 Dec 23
The present invention aims to develop a method for treating COVID-19 caused by SARS-CoV-2 or a mutant strain thereof, and provides an agent for preventing and/or treating COVID-19 caused by SARS-CoV-2 or a mutant strain thereof, the agent comprising a specific compound.
Mitsuyoshi AZUMA, Chiho FUKIAGE, Takashi IMADA, Yayoi KISHIMOTO, Noriyasu HIRASAWA, Yoshiro SAITO, Takashi TOYAMA
Filed: 29 Oct 21
Utility
Corneal Endothelium Ecm Therapeutic Medicaments
5 Oct 23
The present invention provides medicaments for treating or preventing a disease, disorder, or condition associated with extracellular matrix (ECM) abnormality in a corneal endothelium, wherein the medicaments comprise a TGF-beta signal inhibiting agent.
Noriko KOIZUMI, Naoki OKUMURA, Shigeru KINOSHITA
Filed: 7 Jun 23
Utility
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6 Jul 23
The invention provides an agent for promoting adhesion of a corneal endothelial cell, containing a Rho kinase inhibitor, as well as a culture medium for a corneal endothelial cell, a solution for preservation of cornea, and a method of producing a corneal endothelial preparation, which includes culturing the corneal endothelial cell using the aforementioned culture medium.
Noriko KOIZUMI, Shigeru KINOSHITA, Morio UENO
Filed: 13 Mar 23
Utility
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4 May 23
Provided are a bodily fluid-collecting device that is capable of collecting a fixed amount of bodily fluid while minimizing damage to a living body, a method for collecting a bodily fluid using the device, and a method for collecting an aqueous humor using the device A bodily fluid-collecting device 1 comprises a needle part 2 having a needle tube 3 with a needle tip 32, and a capillary 5 removably connected to a base end part 33 of the needle tube 3 in its longitudinal direction on a side opposite to the needle tip 32.
Ryo YOSHINAGA, Tatsuya SAKAI
Filed: 26 Mar 21
Utility
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30 Mar 23
The present disclosure provides the use of a polyether compound.
Noriaki NISHIDA
Filed: 2 Feb 21
Utility
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26 Jan 23
Tomoyo MIYABE, Shinnosuke MACHIDA, Yuka OBA
Filed: 3 Jul 20
Utility
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24 Nov 22
This disclosure provides a means for treating dry eye.
Takeshi TARUI, Shinya KOBAYASHI
Filed: 2 Oct 20
Utility
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24 Nov 22
The present disclosure provides a novel use of nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR).
Masao Doi, Takeshi Nakajima, Mamiko Machida
Filed: 24 Jun 20
Utility
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22 Sep 22
The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress.
Noriko KOIZUMI, Naoki OKUMURA, Shigeru KINOSHITA
Filed: 3 Jun 22
Utility
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14 Jul 22
The present disclosure provides a marker that shows a relationship with changes in the nerve density and morphology in the cornea.
Jun SHIMAZAKI
Filed: 24 Apr 20
Utility
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30 Jun 22
The purpose of the present invention is to provide a composition for preventing or treating neurotrophic keratitis.
Takeshi NAKAJIMA, Mamiko MACHIDA, Shuhei YAMADA
Filed: 14 May 20
Utility
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11 Nov 21
The present invention relates to a retinal ganglion cell death suppressor comprising a BMPR signal transduction inhibitor, a drug comprising a BMPR signal transduction inhibitor for protecting retinal neurons, and a pharmaceutical composition using these for preventing or treating a disease involving retinal ganglion cell death, such as glaucoma, diabetic retinopathy and retinal vascular occlusion.
Yayoi KISHIMOTO, Chiho YABUTA
Filed: 28 Oct 19
Utility
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2 Sep 21
The objective of the present invention is to provide a hydrogel having a favorable shape stability not only after releasing an anionic drug contained but also in the process of releasing such an anionic drug, compared with the conventional techniques; and an anionic drug-containing ophthalmic device obtained by applying the hydrogel.
Yuki ITO, Yasuka WATANABE, Sho KODA, Toru MATSUNAGA, Takao SATO
Filed: 25 Jun 19
Utility
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18 Mar 21
The present disclosure provides a composition for treating or preventing symptoms, disorders, or diseases of the corneal endothelium.
Noriko KOIZUMI, Naoki OKUMURA, Mayumi YAMAMOTO
Filed: 13 Dec 18
Utility
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4 Nov 20
The purpose of the present invention is to provide a PACAP peptide having increased stability.
Shinnosuke MACHIDA, Takeshi NAKAJIMA
Filed: 13 Nov 18
Utility
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23 Sep 20
The purpose of the present invention is to provide a peptide which has a neuroprotective action, a neuroprotective drug and neuropathic treatment containing said peptide, and a preventive or alleviative pharmaceutical composition.
Takeshi NAKAJIMA, Mamiko MACHIDA, Yujiro HAYASHI
Filed: 29 Mar 17
Utility
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26 Aug 20
Noriyuki Azuma, Taku Tanaka, Tadashi Yokoi
Filed: 2 Mar 20
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