275 patents
Utility
Glucocorticoid Receptor Agonists
18 Jan 24
Adel Ahmed Rashad AHMED, Joshua Ryan CLAYTON, Jose Eduardo LOPEZ, William Thomas MCMILLEN, Ryan Edward STITES, Takako WILSON, Jacqueline Mary WURST
Filed: 8 Sep 23
Utility
Devices and Processes for Delivery of Therapeutic Fluids
11 Jan 24
A therapeutic agent delivery system includes a therapeutic agent delivery assembly carried by a housing.
William Godwin ATTERBURY, Corrie Jo BENNISON, Yelena N. DAVIS, David Arthur HOLLEY, John Paul TALLARICO, Jessica Diane YOUNG
Filed: 1 Sep 21
Utility
ANTI-N3pGlu AMYLOID BETA ANTIBODIES AND USES THEREOF
11 Jan 24
The invention is directed to treatment or prevention of a disease characterized by deposition of Aβ in the brain using anti-N3pGlu Aβ antibodies.
Adam S. FLEISHER, Mark MINTUN, John Randall SIMS, II, JonDavid SPARKS
Filed: 11 Jan 22
Utility
Hub for Reusable Drug-delivery Device
4 Jan 24
A recharging and medication storage hub for a re-usable drug-delivery device is provided.
Alexander Joseph BAKER, Kevin Harrison DUFFY, Kaitlyn Mary EDDY, Dae Il KWON, Labi SHRESTHA, Rhea SIRKAR
Filed: 5 Jan 22
Utility
Methods for Reducing Host Cell Protein Content In Antibody Purification Processes and Antibody Compositions Having Reduced Host Cell Protein Content
21 Dec 23
The present disclosure relates to methods for reducing host cell protein content in antibody preparation recombinantly produced in a host cell in the manufacturing process of antibodies intended for administration to a patient.
Brian David BOWES, Lara Ellen KREBS, Lihua HUANG, Steven A. PLICHTA, Sarah M. RICHER
Filed: 4 Oct 21
Utility
Devices and Processes for Delivery of Therapeutic Fluids
14 Dec 23
A therapeutic agent delivery system includes a therapeutic agent delivery assembly carried by a housing.
William Godwin ATTERBURY, Timothy Mark BLUM, Yelena N. DAVIS, David Arthur HOLLEY, John Paul TALLARICO, Jessica Diane YOUNG
Filed: 1 Sep 21
Utility
Medication Delivery Device with Moisture Sensing System
7 Dec 23
Medication delivery devices are provided having a housing comprising a reservoir sized sufficiently to hold medication, a dose button being rotatable relative to the housing to select a dose size of the medication for an injection, a printed circuit board, a conductive trace, and a microcontroller.
Matthew James ASH, Emil PREDA, Andrew Eric BOWYER, Robert Eugene TRZYBINSKI
Filed: 19 Oct 21
Utility
cGAS INHIBITORS
7 Dec 23
The present invention relates to novel cGAS inhibitor compounds, to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions.
Adel AHMED, Christina MARTINEZ BROKAW, Cheryl Ann CARSON, Scott E. CONNER, Kevin Charles FORTNER, Jeffry B. FRANCISKOVICH, Douglas L. GERNERT, Steven J. GREEN, Charles W. LUGAR, III, Jothirajah MARIMUTHU, Shanthi NAGARAJAN, Christodoulos NICOLAOU, Emmanuel ONOBUN, Stephanie Lange STOUT, Eric G. TROMICZAK, Thibault VARIN
Filed: 1 Jun 23
Utility
Oral Drug Delivery Device with Expanding Arms
30 Nov 23
The present disclosure provides a drug delivery device.
Maria Fernandez-Martos BALSON, Matthew Keith FORDHAM, Jack Alexander HORNSBY, Nikolaos Sotirios VASILAKIS, Sarah Louise CLARK
Filed: 15 Sep 21
Utility
Lasofoxifene Combination Treatment of Er+ Breast Cancer That Has Progressed on a CDK4/6 Inhibitor
30 Nov 23
Methods for reducing the progression of ER+ breast cancer in a patient are provided, the methods comprising administering to the patient an effective amount of lasofoxifene or a pharmaceutically acceptable salt thereof and an effective amount of a CDK4/6 inhibitor (CDK4/6i), wherein the breast cancer: (i) is estrogen receptor positive (ER+); (ii) has at least one gain of function missense mutation within the ligand binding domain (LBD) of the Estrogen Receptor 1 (ESR1) gene; and (iii) has progressed during prior CDK4/6 inhibitor therapy and/or has an oncogenic mutation in a gene other than ESR1.
David J. PORTMAN, Paul PLOURDE, Simon JENKINS
Filed: 25 May 23
Utility
Phenyl-3,4-dihydroisoquinolin-2(1h)-yl-ethan-1-one derivatives as dopamine d1receptor positive allosteric modulators
30 Nov 23
Junliang HAO, Richard D. JOHNSTON, Gregory Lawrence LACKNER, Erik J. HEMBRE, Kjell A. SVENSSON
Filed: 5 Oct 21
Utility
Secured Medication Transfer System
23 Nov 23
A vial adaptor and needle assembly are disclosed for use with a vial containing a medication, such as insulin.
Keith Daniel Alsberg, Christopher John DeMaria, Kenneth James Micklash, II, Gary Harlan Paulsen
Filed: 2 Aug 23
Utility
Methods for Reducing Host Cell Protein Content In Protein Purification Processes
23 Nov 23
The present disclosure relates to methods for reducing host cell protein content in a protein preparation recombinantly produced in a host cell in the manufacturing process of proteins intended for administration to a patient.
Brian David Bowes, Lara Ellen Krebs
Filed: 4 Oct 21
Utility
PHENYL-2-HYDROXY-ACETYLAMINO-2-METHYL-PHENYL Compounds for the Treatment of Pancreatic Cancer
23 Nov 23
The present invention provides phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds, to pharmaceutical compositions comprising the compounds, to methods of using the compounds to treat physiological disorders such as cancer.
Marta Maria Cifuentes-Garcia, Maria Cristina Garcia Paredes
Filed: 13 Apr 23
Utility
6-METHOXY-3,4-DIHYDRO-1H-ISOQUINOLIN Compounds
23 Nov 23
Ana Belén BUENO MELENDO, Jayana Pankajkumar LINESWALA, Gema RUANO PLAZA, Nuria Diaz BUEZO
Filed: 6 Oct 21
Utility
AT2R Antagonists and Uses Thereof
23 Nov 23
Thomas James BEAUCHAMP, Zhaogen CHEN, Scott Eugene CONNER, Jon Andre ERICKSON, Maria Cristina GARCIA PAREDES, Jayana Pankajkumar LINESWALA, Emanuele SHER, Bishnu THAPA, Leonard Larry WINNEROSKI, II
Filed: 11 May 23
Utility
Devices and Processes for Delivery of Therapeutic Fluids
16 Nov 23
A therapeutic agent delivery system includes a therapeutic agent delivery assembly carried by a housing.
William Godwin ATTERBURY, Corrie Jo BENNISON, Yelena N. DAVIS, Jeffrey LeClair ELLIS, David Arthur HOLLEY, John Paul TALLARICO, Jessica Diane YOUNG
Filed: 1 Sep 21
Utility
Oral Drug Delivery Device with Expanding Band
9 Nov 23
The present disclosure provides a drug delivery device.
Eric Gustin HASSENPFLUG, Anthony David DUONG, Erik William EDWARDS, Brian R. FORTNER, Larry Keith HOOKS, Jr., Steven HUCKABY, Trevor Alan PETREL, Sarah Louise CLARK
Filed: 15 Sep 21
Utility
Medication Delivery Device with Sensing System
9 Nov 23
Medication delivery devices are provided having a sensor in the form of a single-pole double-throw (SPDT) switch, a conversion control module that receives signals from the SPDT switch and generates an outputs a signal, and related power control circuitry.
Andrew Eric BOWYER, Joseph Edward KATUIN
Filed: 23 Aug 21
Utility
Therapeutic Uses of Tirzepatide
9 Nov 23
The present invention relates to methods for treating, preventing or delaying disorders relating to cognition, such as cognitive decline, cognitive impairment or dementia.
Matthew Paul COGHLAN, Axel HAUPT, Masahiro MURAKAMI, Jeffrey Scott RIESMEYER
Filed: 22 Jan 21