79 patents
Page 4 of 4
Utility
Hydrophilic Anion Exchange Chromatography Media
30 Sep 20
An anion exchange stationary phase comprises substrate particles, a based condensation polymer layer attached to the substrate particles, one or more alkylamine condensation polymer layers covalently attached to base condensation polymer layer, and a terminating condensation layer covalently attached to the alkylamine condensation polymer layer.
Christopher A. Pohl, Manikandan JAYARAMAN
Filed: 28 Mar 19
Utility
Anion exchange stationary phases based on crosslinked hydroxyalkylamine layer and glycidol
14 Sep 20
An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer.
Charanjit Saini, Christopher A. Pohl
Filed: 21 Mar 18
Utility
Anion exchange stationary phases based on crosslinked hydroxyalkylamine layer and glycidol
7 Sep 20
An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer.
Charanjit Saini, Christopher A. Pohl
Filed: 9 Aug 18
Utility
Ion Exchange Chromatography Column, Method, and System Thereof
19 Aug 20
An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles.
Manikandan JAYARAMAN, Christopher A. POHL, Charanjit SAINI
Filed: 3 May 20
Utility
Method and device to extract an analyte from a sample with gas assistance
17 Aug 20
A method of extracting an analyte from a sample is described.
Kannan Srinivasan, SM Rahmat Ullah
Filed: 9 Aug 16
Utility
Suppressors with Eluent Screens for Use In Ion Chromatography
29 Jul 20
A suppressor for use in reducing a background signal while detecting analytes in a liquid sample for ion chromatography is described.
Kannan SRINIVASAN, Sheetal BHARDWAJ, Glenn M. KUSE
Filed: 24 Jan 19
Utility
Ion exchange chromatography column, method, and system thereof
4 May 20
An ion exchange chromatographic packing material is described that includes support resin particles and a copolymer grafted to the support resin particles.
Manikandan Jayaraman, Christopher A. Pohl, Charanjit Saini
Filed: 18 Jun 15
Utility
Systems, methods and devices for width-based analysis of peak traces
27 Apr 20
Systems, methods and devices are taught for providing analytical methods for peak-shaped responses separated in time or space, including quantitation of chromatographic peaks based on a width measurement of a peak trace at a selected height as a quantitation element.
Purnendu K. Dasgupta, Akinde F. Kadjo, Kannan Srinivasan
Filed: 27 Nov 17
Utility
Replaceable emitter assembly for interfacing a separation column to a mass spectrometer
20 Apr 20
An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed.
Brandon Howard Robson, Xuefei Sun, Xiaodong Liu
Filed: 12 Jul 17
Utility
Automated method of calibrating a chromatography system and analysis of a sample
30 Mar 20
An automated method of calibrating a chromatography system and analyzing a sample is described.
Kannan Srinivasan, Christopher A. Pohl
Filed: 25 Sep 17
Utility
Vial Cap and Method for Removing Matrix Components from a Liquid Sample
4 Mar 20
A vial cap for removing a matrix component from a liquid sample is described.
Christopher A. POHL, Rosanne W. SLINGSBY
Filed: 6 Nov 19
Utility
Method and device to extract an analyte from a sample with gas assistance
24 Feb 20
A method of extracting an analyte from a sample is described.
Kannan Srinivasan, SM Rahmat Ullah
Filed: 9 Aug 16
Utility
Suppressor device
24 Feb 20
An apparatus for detecting analytes in a liquid sample may include an elongated primary channel through which an ionic species flows, the primary channel extending through a primary channel member, a first regenerant channel through which a regenerant flows, the first regenerant channel extending adjacent to the primary channel and being formed in a first block, a first charged barrier having exchangeable ions capable of passing ions of only one charge, positive or negative, and of blocking bulk liquid flow, the first charged barrier disposed between the primary channel member and the first block for separating the primary channel from the first regenerant channel, and a first sealing member disposed between the first charged barrier and the first block defining the first regenerant channel.
Kannan Srinivasan, Glenn M. Kuse, Rong Lin, Sheetal Bhardwaj
Filed: 15 Jul 18
Utility
Anion Exchange Stationary Phases Based on Crosslinked Hydroxyalkylamine Layer and Glycidol
12 Feb 20
An anion exchange stationary phase includes a negatively charged substrate particle, a base condensation polymer layer, a crosslinked ethanolamine condensation polymer, and a glycidol condensation layer.
Charanjit SAINI, Christopher A. POHL
Filed: 9 Aug 18
Utility
Anion Exchange Stationary Phases Based on a Polyalkylpolyamine Polymer Layer
29 Jan 20
An anion exchange for separating a plurality of carbohydrates includes a negatively charged substrate particle.
Christopher A. POHL, Jinhua CHEN
Filed: 29 Jul 18
Utility
Vial cap and method for removing matrix components from a liquid sample
2 Dec 19
A vial cap for removing a matrix component from a liquid sample is described.
Christopher A. Pohl, Rosanne W. Slingsby
Filed: 29 Dec 14
Utility
Multimodal Chromatographic Media for Protein Separation
27 Nov 19
A chromatographic media for separating bio-polymers, the chromatographic media having cationic exchange properties and anionic exchange properties, the chromatographic media comprising: (a) non-porous substrate particles including an organic polymer, the substrate particles having a neutral hydrophilic layer at a surface of the non-porous substrate particles, in which the neutral hydrophilic layer is configured to reduce a binding of the bio-polymers directly to the non-porous substrate particles compared to a binding of the bio-polymer to the non-porous substrate particles without the neutral hydrophilic layer; (b) a charged first ion exchange layer bound to the substrate particles on top of the hydrophilic layer, the first ion exchange layer comprising first ion exchange groups; and (c) a charged second ion exchange layer bound to the substrate particles on top of the first ion exchange layer.
Christopher A. Pohl, Xiaodong Liu, Shanhua Lin Liehr
Filed: 17 Jan 18
Utility
Ion Exchange Based Volatile Component Removal Device for Ion Chromatography
23 Oct 19
A method, device, and system for removing a volatile component from a liquid solution for a chromatographic separation are described.
Kannan SRINIVASAN, Sheetal BHARDWAJ
Filed: 25 Apr 19
Utility
Methods and systems for detection of non-volatile solutes
30 Sep 19
A system for detection of non-volatile solutes dissolved in solution comprises: a spray emitter system configured to receive a flow of the solution and generate an aerosol comprising droplets thereof, the generated droplets comprising a restricted size range; a spray chamber configured to receive the aerosol and emit a modified aerosol comprising droplets having a diameter smaller than a predetermined value; a conduit configured to receive a flow of the modified aerosol and to evaporate the solvent so as to generate an aerosol comprising solid particles of the solutes; a charging chamber configured to receive the aerosol and impart electric charge to the solid particles; and a detector configured to measure a quantity of charge imparted to the solid particles, wherein the restricted size range is such that solid particles having diameters greater than 10 nm comprise a substantial portion of all particles received by the charging chamber.
Paul H. Gamache
Filed: 21 Jun 16