39 patents
Utility
System for Electrospray Ionization with Integrated LC Column and Electrospray Emitter
26 Oct 23
An integrated system for liquid separation and electrospray ionization includes an emitter-enabled capillary column including an emitter portion and a column portion; and a retractable protective sleeve for covering and/or supporting the emitter portion along at least a portion of its axis.
Brandon Howard Robson, Xuefei Sun, Carla Marie Medlin, Shane Bechler
Filed: 26 Jun 23
Utility
Monitoring and Mitigating Suppressor Failure
26 Oct 23
A suppressor comprising one or more channels, a flow path for each of the channels, and one or more measurement probes positioned in the flow path is described.
Yongjing Chen, Yan Liu
Filed: 20 Mar 23
Utility
Extraction Cell Cap Assembly with Toolless Disassembly
31 Aug 23
An extraction cell cap assembly allows for toolless disassembly.
Weichiat Chen, Kannan Srinivasan
Filed: 10 May 23
Utility
Configuration for Ultra High Pressure Electrolytic Eluent Generators
6 Jul 23
An electrolytic eluent generator includes an electrolyte reservoir and at least one eluent generation cartridge.
Zhongqing Lu, Yan Liu, Angelo Rubero, Rong Lin
Filed: 30 Dec 21
Utility
Identification of Sample Cells In a Chromatography Autosampler
29 Jun 23
Methods and systems are provided for the identification of sample cells in a sample tray that is placed in a chromatography autosampler.
Daniel Hoffmeyer, Husam Al-Esawi, Tobias Metz, Til Richardsen, Christoph Hollnagel
Filed: 28 Dec 21
Utility
Identification of Sample Cells In a Chromatography Autosampler
29 Jun 23
Methods and systems are provided for the identification of sample cells in a sample tray that is placed in a chromatography autosampler.
Daniel Hoffmeyer, Husam Al-Esawi, Tobias Metz, Til Richardsen, Christoph Hollnagel
Filed: 24 Feb 22
Utility
Electrolytic Buffer Generator
4 May 23
Buffer generators are described based on electrodialytic devices.
Purnendu K. Dasgupta, Yongjing Chen, Kannan Srinivasan
Filed: 6 Sep 22
Utility
Electrolytic Eluent Generators with Stabilized Operating Voltages
30 Mar 23
An electrolytic eluent generator includes an electrolyte reservoir, an eluent generation chamber, and an ion exchange membrane stack.
Zhongqing LU, Yan LIU, Christopher A. POHL, Jinhua CHEN, Jun CHENG
Filed: 4 Nov 22
Utility
Self-directed Computer System Validation
16 Mar 23
A system for self-directed computer system validation includes first logic to provide a graphical user interface to enable a user to select a set of selected requirements from a plurality of available requirements; second logic to select a set of procedures to satisfy the need to test against each of the requirements and document evidence of the outcomes and generate a set of documents for installing and configuring the system and test protocols including all methods and objects needed to validate the system; and third logic to provide the set of documents for installing and configuring the system and test protocols including all methods and objects needed to validate the system.
Shaun Anders QUINN, Matthew A. GRULKE, Patrick Michael KENNY
Filed: 13 Sep 21
Utility
Novel Automated Valve Switching Setup for Ion Chromatography (IC) that Facilitates Equilibration of Consumables or Allows for Normal IC Operation
9 Mar 23
A chromatography system includes an electrolytic eluent generator; a first valve configured to switch between an operating position which directs an output of the electrolytic eluent generator to a continuously generated trap column and a waste position which directs the output of the electrolytic eluent generator to waste; the continuously regenerated trap column; a degasser; a sample injector including a sample injector valve assembly, the sample injector valve assembly configured to switch between an operation mode which directs an output of the degasser to a separation column, a load mode which loads a sample onto the separation column, and a regenerant mode which directs the output of the degasser to a regenerant line; the separation column; a suppressor; and a detector.
Kannan SRINIVASAN
Filed: 8 Sep 21
Utility
Check Standard Recycle Setup for Ion Chromatography
9 Mar 23
An ion chromatography system includes a separation column configured to separate components of a solution; a non-destructive detector; and a concentrator configured to capture components of a check standard after they leave the conductivity non-destructive detector; and release the components of the check standard to the separation column.
Kannan SRINIVASAN
Filed: 9 Sep 21
Utility
Ion Exchange Stationary Phases For Analyzing Polyvalent Ions
27 Oct 22
Ion exchange stationary phases are prepared with diprimary diamines for applications such as separating samples that contain polyvalent anions.
Christopher A Pohl
Filed: 27 Jun 22
Utility
Coated Poly-olefins
6 Oct 22
A coated substrate that comprises a polyolefin substrate having a functional polymer layer disposed thereon.
John M. Riviello, Christopher A. Pohl
Filed: 22 Dec 21
Utility
Analyte Concentrator System and Methods of Use
28 Jul 22
Systems and methods for concentrating an analyte preparatory to analysis thereof include processing the effluent of an analyte concentrator to produce an eluent for eluting an analyte retained in the same or separate concentrator, and systems implementing the same.
Kannan SRINIVASAN
Filed: 17 Jan 22
Utility
Bioinert Sampling Needle
30 Jun 22
A sampling needle is provided for piercing a septum of a vial containing a sample and aspirating the sample from the vial.
Daniel Hoffmeyer, Licheng Tseng
Filed: 29 Dec 20
Utility
Electrochemical Cell Configured To Have A Dynamically Renewed Electrode
30 Jun 22
An electrochemical cell comprises a chamber, an inlet port, an outlet port, an electrode port, and a counter electrode.
Purnendu Dasgupta, Charles P. Shelor, Kannan Srinivasan, Christopher A. Pohl
Filed: 27 Dec 21
Utility
Method of Separating Viral Vectors
12 May 22
A method of separating a liquid sample containing viral vectors includes flowing the liquid sample into an anion exchange column.
Kenneth George COOK, Alexander Boris SCHWAHN, Jung Un BAEK, Shanhua Lin LIEHR
Filed: 10 Nov 20
Utility
Extraction Cell Cap Assembly with Toolless Disassembly
31 Mar 22
An extraction cell cap assembly allows for toolless disassembly.
Weichiat Chen, Kannan Srinivasan
Filed: 30 Sep 20
Utility
Method for Preparing Monolithic Coated Surfaces
31 Mar 22
A carrier for adsorption a compound, comprising a support; and a shrink-fitted monolithic body attached to and surrounding at least a portion of the support.
Christopher A. POHL, John M. RIVIELLO
Filed: 8 Dec 21
Utility
Peak Profile for Identifying an Analyte in a Chromatogram
10 Feb 22
A method of determining an identity of a first analyte in a sample is described that includes passing the first analyte through a chromatographic column and detecting a signal curve of the first analyte by a chromatographic detector, wherein the signal curve includes a peak profile of the first analyte.
Akinde F. Kadjo, Kannan Srinivasan, Purnendu K. Dasgupta
Filed: 4 Aug 20