104 patents
Page 6 of 6
Utility
Covalent Heterobivalent Antibody Inhibitors and Ligands
11 Dec 19
The invention provides a strategy for site specific covalent modification of antibodies using a specialized targeting covalent heterobivalent ligand (cHBL), and corresponding design for a covalent heterobivalent inhibitor (cHBI) that can be used to prevent Immunoglobulin E (IgE) mediated allergic reactions triggered by drug molecules, according to one embodiment.
Zihni Basar BILGICER, Peter Edward DEAK, Tanyel KIZILTEPE BILGICER, Michael William HANDLOGTEN, Jonathan Darryl ASHLEY
Filed: 18 Dec 16
Utility
Ac Electrosprayed Droplets for Digital and Emulsion PCR
20 Nov 19
The invention provides an alternating current electrospray technology that can generate micron sized droplets in oil at very high throughput for emulsion or digital PCR (Polymerase Chain Reaction).
Hsueh-Chia CHANG, David B. GO, Zdenek SLOUKA, Satyajyoti SENAPATI, Yongfan MEN, Zehao PAN
Filed: 8 May 17
Utility
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20 Nov 19
Marvin J. MILLER, Cheng JI, Paul BOHN, Sean BRANAGAN, Yang YANG
Filed: 11 Dec 18
Utility
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30 Oct 19
A method of crosslinking a hetero-bifunctional photo crosslinking compound to an immunoglobulin having at least one heterocyclic photo reactive group and at least one non-photo reactive group where the non-photo reactive group is coupled to an effector molecule and the photo reactive group is coupled to the nucleotide binding site of an immunoglobulin.
Zihni Basar BILGICER, Nathan J. ALVES
Filed: 23 Jun 19