75 patents
Utility
Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection
21 Nov 23
Described herein are compounds and compositions, and methods of making and their use as effective agents against mycobacterial infections.
Marvin J. Miller, Garrett C. Moraski
Filed: 28 Dec 20
Utility
Refillable drug delivery by affinity homing
7 Nov 23
Described herein are compositions and methods for a novel drug delivery platform using affinity homing.
Matthew J. Webber, Lei Zou
Filed: 5 Apr 19
Utility
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24 Oct 23
An approach for a non-factoid question answering framework across tasks and domains may be provided.
Wenhao Yu, Lingfei Wu, Yu Deng, Qingkai Zeng, Ruchi Mahindru, Sinem Guven Kaya, Meng Jiang
Filed: 7 Jul 21
Utility
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10 Oct 23
An additive manufacturing (AM) device for biomaterials comprises a reservoir, a shaft, and a material delivery head.
David J. Hoelzle
Filed: 3 Dec 20
Utility
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26 Sep 23
Systems and methods for detecting textured contact lenses in an iris image are disclosed.
Adam Czajka, Kevin Bowyer, Zhaoyuan Fang
Filed: 24 Oct 19
Utility
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5 Sep 23
A system and methods of characterizing a population of a virus, bacteriophage, or other microbes in a microbiome that includes the steps of separating a sample of microbiota into more than one fraction by continuous capillary zone electrophoresis based on the physiochemical properties of the microbes in the microbiota using a constant voltage applied to the sample during the continuous zone electrophoresis.
Norman Dovichi, Bonnie Jaskowski Huge, Matthew Champion
Filed: 6 Aug 20
Utility
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22 Aug 23
Substituted nitrobenzothiazinones (BTZs) are potent antituberculosis prodrugs that are reductively activated to produce nitroso moieties that form covalent adducts with a cysteine residue of decaprenylphosphoryl-β-D-ribose-2′-oxi-dase (DprE1) of Mycobacterium tuberculosis (Mtb).
Marvin J. Miller, Viktor Krchnak, Rui Liu
Filed: 3 Apr 20
Utility
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30 May 23
Aspects of the subject disclosure may include, for example, receiving, by a first radio module at a first location, a wireless signal, to obtain a first received RF signal.
Ralf Bendlin, Jonathan David Chisum, Nicholas Joseph Estes, Bertrand Martyn Hochwald, Aditya Chopra
Filed: 25 Feb 22
Utility
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2 May 23
Embodiments of the present disclosure provide a nanoparticle based platform, and nanoallergens for identifying, evaluating and studying allergen mimotopes as multiple copies of a single mimotope or various combinations on the same particle.
Zihni Basar Bilgicer, Peter Edward Deak, Tanyel Kiziltepe Bilgicer, Jared Francis Stefanick, Jonathan Darryl Ashley
Filed: 18 Dec 20
Utility
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7 Mar 23
A method operating a Graphics Processing Unit (GPU) memory can be provided by accessing specified training parameters used to train a Deep Neural Network (DNN) using a GPU with a local GPU memory, the specified training parameters including at least a specified batch size of samples configured to train the DNN.
Xiaobo Sharon Hu, Danny Ziyi Chen, Xiaoming Chen
Filed: 16 Mar 20
Utility
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28 Feb 23
Methods to form a surface coating and surface pattern, which are based on adsorption of hydrocarbon chains that can be used with imaging optics to visualize macrophage fusion and multinucleated giant cell formation with living specimens are described.
James Faust, Tatiana Ugarova, Robert Ros, Wayne Christenson, Kyle Doudrick
Filed: 5 Oct 20
Utility
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28 Feb 23
Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors.
Zhongming Li, Gregory Hartland, Masaru Ken Kuno
Filed: 18 May 20
Utility
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28 Feb 23
Systems and methods for maintaining the safety of a software-based system.
Jane Huang, Michael Vierhauser, Ankit Agrawal
Filed: 15 Oct 19
Utility
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24 Jan 23
The present disclosure encompasses antibacterial compositions and methods of treating bacterial infections caused by resistant bacteria.
Gautam Dantas, Patrick Gonzales, Kevin Forsberg, Mitchell Pesesky, Mayland Chang, Shahriar Mobashery
Filed: 29 Oct 19
Utility
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10 Jan 23
Products, systems, and methods for classifying human colorectal cancer into a consensus molecular subtype (CMS) and for assessing risk of recurrence based on CMS scores and based on risk scores derived from abbreviated gene expression profiles, for determining suitable treatment protocols for human colorectal cancer patients based on the determined CMS classification and based on the determined risk of recurrence, and for administering the suitable treatment protocols.
Steven Buechler
Filed: 7 Mar 19
Utility
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20 Dec 22
An N-bit non-volatile multi-level memory cell (MLC) can include a lower electrode and an upper electrode spaced above the lower electrode.
Kai Ni, Suman Datta, Andrew Kummel
Filed: 25 Sep 20
Utility
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1 Nov 22
In a method computer storage element operation, first and second rising (or falling) clock edges are applied to first and second power inputs of the computer storage element having a transistor array between the first and second power inputs over time T1 whereupon a logic value applied to an input of the transistor array is stored therein.
Gregory Snider, Rene Celis-Cordova, Alexei Orlov, Tian Lu, Jason M. Kulick
Filed: 19 Feb 21
Utility
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25 Oct 22
Aspects of the subject disclosure may include, a non-linear energy detector that obtains baseband information from a mixed signal that corresponds to an information component of a received radio frequency (RF) signal, wherein the mixed signal comprises a local oscillator signal combined, without multiplication, with the received RF signal, wherein the received RF signal comprises a carrier wave component operating at a carrier frequency within a millimeter wave spectrum, wherein the non-linear energy detector is associated with a non-linear current-voltage (I-V) characteristic curve, and wherein the baseband information is obtained by applying the mixed signal to the non-linear I-V characteristic curve.
Ralf Bendlin, Aditya Chopra, Bertrand Martyn Hochwald, Nicholas Joseph Estes, Jonathan David Chisum, Kang Gao
Filed: 30 Jul 21
Utility
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2 Aug 22
Bromine induced lactamization of vinyl acetohydroxamates facilitated syntheses of monocyclic β-lactams suitable for incorporation of a thiomethyl and extended functionality at the C(4) position.
Marvin J. Miller, Serena Carosso, Rui Liu, Patricia Miller
Filed: 2 Oct 18
Utility
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5 Apr 22
The invention provides an alternating current electrospray technology that can generate micron sized droplets in oil at very high throughput for emulsion or digital PCR (Polymerase Chain Reaction).
Hsueh-Chia Chang, David B. Go, Zdenek Slouka, Satyajyoti Senapati, Yongfan Men, Zehao Pan
Filed: 9 May 17