75 patents
Page 3 of 4
Utility
Methods and apparatus for a shear-enhanced CNT-assembly nanosensor platform for ultra-sensitive and selective protein detection
23 Mar 21
A nanoscale protein-sensing platform with a non-equilibrium on-off switch that employs dielectrophoretic and hydrodynamic shear forces to overcome these thermodynamic limitations with irreversible kinetics.
Hsueh-Chia Chang, Diya Li, Satyajyoti Senapati
Filed: 14 Nov 17
Utility
Covalent heterobivalent antibody inhibitors and ligands
16 Mar 21
The invention provides a strategy for site specific covalent modification of antibodies using a specialized targeting covalent heterobivalent ligand (cHBL), and corresponding design for a covalent heterobivalent inhibitor (cHBI) that can be used to prevent Immunoglobulin E (IgE) mediated allergic reactions triggered by drug molecules, according to one embodiment.
Zihni Basar Bilgicer, Peter Edward Deak, Tanyel Kiziltepe Bilgicer, Michael William Handlogten, Jonathan Darryl Ashley
Filed: 19 Dec 16
Utility
Electricity generation from low grade waste heat
2 Mar 21
Systems and methods for generating electricity from low grade heat.
Tengfei Luo, Shirui Luo
Filed: 22 Mar 19
Utility
Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection
16 Feb 21
Described herein are compounds and compositions, and methods of making and their use as effective agents against mycobacterial infections.
Marvin J. Miller, Garrett C. Moraski
Filed: 19 Sep 16
Utility
Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same
9 Feb 21
Embodiments relate to the field of chemistry and biochemistry, and, more specifically, to imidazopyridine compounds, synthesis thereof, and methods of using same.
Marvin J. Miller, Garrett C. Moraski, Lowell D. Markley, George E. Davis
Filed: 5 Feb 18
Utility
Closed bipolar electrode-enabled electrochromic detector for chemical sensing
2 Feb 21
The described BPE-enabled device includes two separated chambers which perform detection and reporting independently.
Paul W. Bohn, Wei Xu, Kaiyu Fu, Chaoxiong Ma
Filed: 11 Aug 17
Utility
Additive manufacturing device for biomaterials
12 Jan 21
An additive manufacturing (AM) device for biomaterials comprises a reservoir, a shaft, and a material delivery head.
David J. Hoelzle
Filed: 11 May 17
Utility
Ionic liquids comprising heteraromatic anions
12 Jan 21
Some embodiments described herein relate to ionic liquids comprising an anion of a heteraromatic compound such as optionally substituted pyrrolide, optionally substituted pyrazolide, optionally substituted indolide, optionally substituted phospholide, or optionally substituted imidazolide.
William F. Schneider, Joan F. Brennecke, Edward J. Maginn, Elaine Vazquez, Burcu Gurkan, Erica Price, Brett Goodrich
Filed: 4 Sep 18
Utility
Exosomal biomarkers diagnostic of tuberculosis
12 Jan 21
A method for diagnosing an active Mycobacterium tuberculosis infection by detecting certain RNA biomarkers present in secreted extracellular vesicles isolated from a bodily fluid.
Jeffrey S. Schorey, Prachi Pratap Singh, Yong Cheng
Filed: 21 Nov 19
Utility
Nanoallergens and uses thereof
28 Dec 20
Embodiments of the present disclosure provide a nanoparticle based platform, and nanoallergens for identifying, evaluating and studying allergen mimotopes as multiple copies of a single mimotope or various combinations on the same particle.
Zihni Basar Bilgicer, Peter Edward Deak, Tanyel Kiziltepe Bilgicer, Jared Francis Stefanick, Jonathan Darryl Ashley
Filed: 25 Sep 16
Utility
Mitigating beam squint in millimeter wave wireless communication systems
26 Oct 20
A method for managing beam squint in a phased antenna array system operating at millimeter wavelengths using carrier aggregation includes determining a minimum array gain threshold, determining an upper bound for a fractional bandwidth for a fixed number of antennas, and constructing a codebook with a predetermined coverage range based on at least one of an angle of arrival or an angle of departure and further based on the upper bound.
Mingming Cai, J. Nicholas Laneman, Bertrand Hochwald
Filed: 3 Dec 18
Utility
Ionic liquid-based absorption cooling system with high coefficient of performance
19 Oct 20
An absorption refrigeration system (ARS), includes a sorbent-refrigerant pair that has an ionic liquid (IL) sorbent and a refrigerant that displays a lower critical lower critical solution temperature (LCST) at a temperature of 50 to 100° C., wherein the separation of the sorbent from the refrigerant occurs upon heating the sorbent-refrigerant pair to a temperature above the LCST.
Saeed Moghaddam, Abhilash Paneri, Edward Maginn
Filed: 26 Sep 16
Utility
Optical-quality surface that imparts spatial control of macrophage fusion
12 Oct 20
Methods to form a surface coating and surface pattern, which are based on adsorption of hydrocarbon chains that can be used with imaging optics to visualize macrophage fusion and multinucleated giant cell formation with living specimens are described.
James Faust, Tatiana Ugarova, Robert Ros, Wayne Christenson, Kyle Doudrick
Filed: 7 Sep 17
Utility
Enhanced cosite transmitter-receiver isolation
12 Oct 20
Systems and methods for improving isolation between a cosite transmitter-receiver system.
Thomas G. Pratt, Robert Daniel Kossler
Filed: 10 Apr 17
Utility
Use of coherent signal dispersion for signal source association
6 Jul 20
A signal source association method and receiver.
Thomas G. Pratt, Robert Daniel Kossler, Jeffrey G. Mueller, Joseph Lawrence Loof
Filed: 19 Apr 16
Utility
Method for preparing largazole analogs and uses thereof
8 Jun 20
Analogs of largazole are described herein.
Robert M. Williams, James E. Bradner, Dane Clausen, Olaf G. Wiest, Tenaya L. Newkirk, Albert A. Bowers, Jennifer Marie Guerra
Filed: 2 Mar 16
Utility
Photothermal imaging device and system
8 Jun 20
Mid-infrared photothermal heterodyne imaging (MIR-PHI) techniques described herein overcome the diffraction limit of traditional MIR imaging and uses visible photodiodes as detectors.
Zhongming Li, Gregory Hartland, Masaru Ken Kuno
Filed: 4 Apr 17
Utility
Ultra-sensitive multi-target lateral flow molecular assay with field-induced precipitation
1 Jun 20
Described are methods for detecting and quantifying biomolecules such as polynucleotides or polypeptides in an electrophoresis matrix using ion concentration polarization and nanoparticle aggregation.
Steve Marczak, Hsueh-Chia Chang, Zdenek Slouka, Satyajyoti Senapati
Filed: 30 May 18
Utility
Non-beta lactam antibiotics
25 May 20
The invention provides a newly discovered oxadiazole class of antibiotics.
Mayland Chang, Shahriar Mobashery, Edward Spink, Derong Ding, Sebastian Testero, Erika Leemans, Marc Boudreau
Filed: 24 Sep 15
Utility
Methods and systems for inferring network structure from cascades
11 May 20
Disclosed herein are systems, methods, and software for providing a network structure for a network.
Dervis Can Vural, Sushrut Ghonge
Filed: 21 Feb 18