1904 patents
Page 2 of 96
Utility
Sampler for liquid chromatography
9 Jan 24
A sampler for liquid chromatography is described.
Thomas Wachinger
Filed: 7 Apr 22
Utility
Fluorogenic pH sensitive dyes and their method of use
9 Jan 24
Jeffrey Dzubay, Kyle Gee, Vladimir Martin, Aleksey Rukavishnikov, Daniel Beacham
Filed: 21 Sep 20
Utility
Lipid Compositions For In Vivo Delivery
4 Jan 24
Provided herein, are compositions, methods and kits for inducing an immune response in a subject.
Evgenia VEROVSKAYA, Joel JESSEE
Filed: 29 Jun 23
Utility
Charged Particle Beam Device for Inspection of a Specimen with a Plurality of Charged Particle Beamlets
4 Jan 24
The invention relates to a charged particle beam device for inspection of a specimen with a plurality of charged particle beamlets.
Ali Mohammadi-Gheidari, Erik René Kieft, Pieter Kruit
Filed: 26 Jul 22
Utility
Enzymatic Ligation of Nucleic Acids
4 Jan 24
Methods, assays, compositions and kits for the ligation of short polynucleotides are presented herein.
Stephen HENDRICKS, David J. KING
Filed: 20 Apr 23
Utility
Switchable-path Ion Guide
4 Jan 24
An ion guide with a switchable ion path for a spectrometer includes a first ion transport aperture configured to receive an ion beam.
Hamish Stewart
Filed: 28 Jun 23
Utility
Systems and Methods for Annotating Biomolecule Data
4 Jan 24
Systems, methods, software and computer-usable media for annotating biomolecule-related data are disclosed.
Liviu POPESCU, Flona HYLAND
Filed: 21 Jun 23
Utility
Methods for Assessing Genomic Instability
4 Jan 24
Methods for assessing genomic instability (GI) may include selectively amplifying nucleic acid sequences at targeted locations in a tumor sample genome by a targeted panel with a low sample input to generate a plurality of nucleic acid sequence reads; dividing the genome into segments having homogeneous copy numbers using log odds of heterozygous SNPs and CNV log ratios determined for the nucleic acid sequence reads; applying a threshold count to squared allelic log odds of each segment in autosomes of the genome to identify unbalanced copy number (UCN) segments; adding numbers of bases in the UCN segments to produce a sum of UCN bases; and dividing the sum of UCN bases by the total number of bases in all the segments identified in the autosomes of the sample genome to produce a ratio indicative of genomic instability.
Mohit GUPTA
Filed: 29 Jun 23
Design
Cell counter display screen with graphical user interface
2 Jan 24
Laurel Stone, Emily Zink, Sean Zimmerman, Nicholas Diliani
Filed: 24 Mar 23
Utility
Compositions and methods for enhanced fluorescence
2 Jan 24
This disclosure relates to the field of fluorescent dyes, and in particular, compositions and methods for increasing fluorescent signals and the reduction of fluorescent quenching.
Surbhi Desai, Marie Christine Nlend, Kyle Gee, Matthew Baker, Robert Aggeler, Scott Sweeney, Aleksey Rukavishnikov, Shih-Jung Huang
Filed: 11 Mar 20
Utility
Method of carrying out a bioreaction with multiple coupled vessels
2 Jan 24
A method of carrying out a bioreaction in a multivessel bioreactor system may include flowing a culture medium at an initial flow rate through one or more fluidic paths between a master vessel and one or more slave vessels, detecting a first culture medium parameter value in the master vessel or the slave vessels, transmitting the first culture medium parameter value to a control system, determining an adjusted flow rate of the culture medium at the control system based on the first culture medium parameter value, and controlling a bidirectional fluid transfer device with the control system to adjust the flow rate of the culture medium through the one or more fluidic paths.
Barbara Paldus, Mark Selker
Filed: 22 Feb 22
Utility
Optical systems and methods for sample separation
2 Jan 24
A system for separating biological molecules includes a plurality of capillaries, a capillary mount, a plurality of optical fibers, a fiber mount, an optical detector, and a motion stage.
Shaohong Wang
Filed: 17 Jan 23
Utility
Switchable ion guide
2 Jan 24
An ion optical arrangement (1) for use in a mass spectrometer comprises a collision cell defining an ion optical axis along which ions may pass, electrodes comprising a set of parallel poles (11A, 11B, 11C) arranged in the collision cell, and a voltage source for providing voltages to the electrodes to produce electric fields.
Henning Wehrs, Johannes Schwieters, Gerhard Jung
Filed: 19 May 20
Utility
Method implemented by a data processing apparatus, and charged particle beam device for inspecting a specimen using such a method
2 Jan 24
The invention relates to a method implemented by a data processing apparatus, comprising the steps of receiving an image; providing a set-point for a desired image quality parameter of said image; and processing said image using an image analysis technique for determining a current image quality parameter of said image.
Remco Schoenmakers, Maurice Peemen, Pavel Poto{hacek over (c)}ek
Filed: 20 Apr 21
Utility
Compositions and Methods for Immune Repertoire Monitoring
28 Dec 23
The present disclosure provides methods, compositions, kits, and systems useful in the determination and evaluation of the immune repertoire.
Geoffrey Lowman, Chenchen Yang, Timothy Looney
Filed: 15 May 23
Utility
Ultra-high-speed Rotor
28 Dec 23
A rotor (10) for use in a centrifuge includes a rotor body (12), a drive hub (20), and a balance ring (16, 160).
Sina PIRAMOON
Filed: 27 Oct 21
Utility
Combined Laser and Broad Ion Beam (Bib) Systems for More Efficient Processing of Multiple Samples
28 Dec 23
Systems and methods for operating a combined laser and broad ion beam (BIB) polisher in a sample preparation workflow, are disclosed.
Krishna Kanth NEELISETTY, Petr WANDROL, Ondrej KLVAC, Yakub FAM, Libor NOVAK, Michal HROUZEK
Filed: 19 May 22
Utility
Methods and Apparatus for Processing Fluids
28 Dec 23
A method for processing a fluid includes removably securing a retention member to a vessel that bounds a chamber; inserting a collapsible bag within the chamber of the vessel; securing the bag to the retention member so that the bag is supported within the chamber of the vessel; and dispensing a fluid into a compartment of the collapsible bag supported within the chamber of the vessel.
Michael E. Goodwin, Jacob D. Lee, Whitt F. Woods, Patrick L. Draper
Filed: 12 Sep 23
Utility
Focused Ion Beam System and Method
28 Dec 23
An ion beam system for modifying a sample or workpiece surface, comprises: an ion source for generating ions; an ion beam focusing column configured to direct ions from the ion source to form an ion beam and focus the ion beam towards a target area; and a sample stage for receiving and positioning the sample or workpiece at the target area, wherein the ion beam focusing column comprises: an aperture plate having a non-circular beam limiting aperture configured to limit the extent of a transmitted ion beam; and a multipole aberration compensator configured to apply a four-fold astigmatism to the ion beam to compensate spherical aberration produced by one or more lenses in the ion beam focusing column.
Alexander HENSTRA, Galen GLEDHILL
Filed: 22 Jun 23
Utility
Apparatuses, Systems And Methods For Imaging Flow Cytometry
28 Dec 23
The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.
Gregory Kaduchak, Michael Ward
Filed: 8 Sep 23