1002 patents
Page 19 of 51
Utility
Ion Guide
15 Sep 22
An ion guide may comprise a set of plate electrodes, each plate electrode having a plurality of apertures formed therethrough.
Hamish STEWART, Alexander WAGNER, Alexander A. MAKAROV
Filed: 31 May 22
Utility
Optimizing Mass Spectra Signal Quality
15 Sep 22
An optimization control system may receive mass spectra of ions emitted from an ionization emitter toward an inlet of a mass spectrometer and control, based on the mass spectra, an automated motion system to adjust a position of the emitter relative to the inlet.
Bennett S. Kalafut, Joshua A. Silveira, Abhishek Joshi, Eloy R. Wouters
Filed: 10 Mar 21
Utility
Smart Sample Container for Complex Sample Evaluation Workflows
8 Sep 22
Systems and methods for using smart sample containers to manage complex sample evaluation workflows, are disclosed.
Remco SCHOENMAKERS, Engelbertus van WILLIGEN, Reinier PERQUIN, Pepijn KRAMER, Egbert ALGRA, James MCCORMACK, Trond K. VARSLOT, Faruk CAGLAR
Filed: 5 Mar 21
Utility
Support Structure and Method for Focus Adjustment
8 Sep 22
An embodiment of a support structure for adjusting the position of a plurality of optical elements is described that comprises a base plate comprising a centering pin, a first translation slot, and a second translation slot; and a translatable plate configured to operatively couple with a plurality of the optical elements and move relative to the base plate, wherein the translatable plate comprises a centering slot configured to engage with the centering pin, a first cam configured to engage with the first translation slot and control movement of the translatable plate along a first axis, and a second cam configured to engage with the second translation slot and control movement of the translatable plate along a second axis.
Matthew Meyer, Francis Deck
Filed: 2 Mar 22
Utility
Systems and Methods for Identifying Exon Junctions from Single Reads
8 Sep 22
Identification of exon junctions includes obtaining a first read sequence based on a detected plurality of signals of a first sequence.
Paolo Vatta, Onur Sakarya, Heinz Breu, Liviu Popescu, Asim Siddiqui, Fiona Hyland
Filed: 21 Mar 22
Utility
Capillary Electrophoresis Systems, Related Devices, and Related Methods
8 Sep 22
A biological analysis device for performing capillary electrophoresis includes a voltage section configured to generate a voltage differential across a cathode connector and an anode connector, an optical detector system configured to detect light emission from a sample, a temperature regulation section, and a cartridge holding portion configured to receive at least a portion of a removable cartridge comprising one or more capillaries and a separation medium container.
Gary LIM, David LIU, Peng LI, Bin CAO, Kirk HIRANO, Alexander DUKHOVNY, John DIXON
Filed: 24 Mar 22
Utility
Methods, Systems, and Computer Readable Media for Nucleic Acid Sequencing
8 Sep 22
A method for nucleic acid sequencing includes receiving a plurality of signals indicative of a parameter measured for a plurality of defined spaces, at least some of the defined spaces including one or more sample nucleic acids, the signals being responsive to a plurality of nucleotide flows introducing nucleotides to the defined spaces; determining, for at least some of the defined spaces, whether the defined space includes a sample nucleic acid; processing, for at least some of the defined spaces determined to include a sample nucleic acid, the received signals to improve a quality of the received signals; and predicting a plurality of nucleotide sequences corresponding to respective sample nucleic acids for the defined spaces based on the processed signals and the nucleotide flows.
Melville Davey, Simon Cawley, Alan Williams
Filed: 14 Feb 22
Utility
Simplified Source Control Interface
1 Sep 22
A mass spectrometry system having a simplified control interface includes a processor and a memory.
Joshua T. MAZE, Scott T. QUARMBY
Filed: 18 May 22
Utility
Cell Culture Medium Comprising Small Peptides
1 Sep 22
Cell culture media, concentrated media and feeds, methods of manufacturing cell culture media and feeds, and methods of culturing cells are provided.
Shawn BARRETT, Scott JACOBIA
Filed: 16 May 22
Utility
Deconvolution of Mass Spectrometry Data
1 Sep 22
A method for deconvoluting measured mass spectrometry data, the method comprising: receiving measured mass spectrometry data representing at least two molecular moieties each having a respective isotopic pattern, wherein at least two of said isotopic patterns overlap; iteratively filling a set of mass channels to produce an approximated version of the mass spectrometry data, said iterative filling comprising a number of iterations, each iteration comprising filling one or more of the mass channels with a chunk of intensity data according to the isotopic pattern of a respective one of the two or more molecular moieties selected for said iteration; terminating said iterative filling when a fitness criterion is met indicating a fit of the approximated version of the mass spectrometry data to the measured mass spectrometry data; and determining the amount of each molecular moiety that produced the measured mass spectrometry data based on the total amount of fills according to the respective isotopic pattern of said molecular moiety.
Frank Berg, Robert Malek, Kai Fritzemeier
Filed: 25 Mar 22
Utility
Swab Collection Kit
25 Aug 22
A collection system including a storage tray and a swab positioned in the storage tray, wherein the swab is configured to collect a sample comprising one or more microorganisms.
John Marshall STATON
Filed: 5 May 22
Utility
Methods and Systems for Tuning a Mass Spectrometer
25 Aug 22
A tuning system may acquire, from a mass spectrometer during a batch of one or more analytical runs performed with the mass spectrometer, tune data associated with an operating characteristic of the mass spectrometer.
Scott T. QUARMBY, Giacinto ZILIOLI, Charles H. VOGT, Dustin J. KREFT, Nathaniel L. SANDERS, George B. GUCKENBERGER, John G. VOSS
Filed: 2 Mar 22
Utility
Autosamplers for Sampling Liquids
25 Aug 22
An autosampler for sampling liquids is disclosed.
George B. GUCKENBERGER, Giuliano ANTONINI, Riccardo FACCHETTI
Filed: 24 Feb 21
Utility
Microcarrier Filter Bag Assemblies and Methods of Use
25 Aug 22
A filter bag assembly includes: a flexible first sheet; a flexible second sheet overlying and secured to the first sheet so that a compartment is formed therebetween; a porous filter sheet disposed between the first sheet and the second sheet so as to divide the compartment into a first compartment and a second compartment; a first port secured to the second sheet so as to communicate directly with the first compartment; and a second port secured to the second sheet so as to communicate directly with the second compartment, the second port being spaced apart from the first port.
Charles R. Rhodes
Filed: 10 May 22
Utility
Methods, Compositions and Kits for Small Rna Capture, Detection and Quantification
25 Aug 22
Methods, compositions and kits for capturing, detecting and quantifying mature small RNAs are provided herein.
Chunmei LIU, Shoulian DONG, Linda WONG
Filed: 3 Mar 22
Utility
Feedback Mechanism for Biological Safety Cabinet
25 Aug 22
The present invention relates to a feedback mechanism for a biological safety cabinet comprising a glass window and a cover plate in front of the glass window, the feedback mechanism comprises a monitor control component comprising a roller element being fixedly disposed with respect to the cover plate and comprising a rollable roller, and a contact component being fixedly disposed relative to the glass window so that the contact component can move relative to the roller with movement of the glass window, the contact component comprising a recess for receiving the roller, wherein the contact component moves with the glass window to a position corresponding to the roller when the glass window moves relative to the cover plate, such that the roller rolls into the recess, allowing the feedback mechanism to generate tactile feedback.
Max Yao, Sean Shang, Yi Zhou, Julia Geng
Filed: 18 Feb 22
Utility
Method and Apparatus for Analysing Samples of Biomolecules Using Mass Spectrometry with Data-Independent Acquisition
18 Aug 22
A mass spectrometry method comprises: providing a multiplexed sample comprising a mixture of biomolecule-containing samples respectively tagged with mass tags; acquiring MS2 spectra by data-dependent acquisition (DDA) of the multiplexed sample or another mass tagged mixture of the samples during chromatographic elution; acquiring MS2 spectra by data-independent acquisition (DIA) during the elution; forming a spectral library from the DDA MS2 spectra comprising a plurality of the MS2 spectra and the biomolecule retention times; matching fragment-ion peaks in the DIA MS2 spectra to fragment-ion peaks in the MS2 library spectra to find matched biomolecules; determining a total abundance for each matched biomolecule from the DIA MS2 spectra at each of a plurality of retention times; determining abundances of respective reporter ions from the DIA MS2 spectra at the plurality of retention times; and deconvoluting relative abundances of the biomolecules in each respectively tagged biomolecule-containing sample based on the determined abundances.
Roman ZUBAREV, Christian BEUSCH
Filed: 16 Feb 22
Utility
Methods and Apparatus for Detecting Molecular Interactions Using Fet Arrays
18 Aug 22
Methods and apparatuses relating to large scale FET arrays for analyte detection and measurement are provided.
Jonathan M. ROTHBERG, Wolgang Hinz
Filed: 2 Mar 22
Utility
a Sliding Door Assembly for an Icp Torch Box
18 Aug 22
A sliding door assembly (50) for an inductively coupled plasma torch box (40) reduces the risk of heat related injuries and facilitates the handling of the torch box.
Tobias Wolf, Jan RATHKAMP, Yannick PIERO
Filed: 30 Jul 20
Utility
3D Fiducial for Precision 3D Nand Channel Tilt/shift Analysis
11 Aug 22
Systems for and methods for generating precise structure reconstruction using slice and view images, are disclosed.
Mark NAJARIAN, Victoriea BIRD, Peter D. CARLESON, Sean MORGAN-JONES
Filed: 9 Feb 21