Fidelity Advisor Health Care Fund

Fund Profile

Fund profile

Tickers

FACDX, FHCCX, FACTX, FHCIX, FIKCX

Fund manager

Fidelity Advisor Biotechnology Fund

Total assets

$4.69 bn

Liabilities

$158.30 mm

Net assets

$4.53 bn

Number of holdings

117.00

117 Holdings

As of Oct 2024

Security	$Holding	Balance	% of Fund	Category	Position	Country
BSX Boston Scientific Corporation	443.63 mm	5.28 mm shares	9.80	Common equity	Long	USA
UNH UnitedHealth Group Incorporated	352.81 mm	625.00 k shares	7.79	Common equity	Long	USA
LLY Eli Lilly and Company	315.30 mm	380.00 k shares	6.96	Common equity	Long	USA
DHR Danaher Corporation	257.94 mm	1.05 mm shares	5.70	Common equity	Long	USA
PEN Penumbra, Inc.	187.67 mm	820.00 k shares	4.14	Common equity	Long	USA
Fidelity Securities Lending Cash Central Fund	153.14 mm	153.12 mm shares	3.38	Short-term investment vehicle	Long	USA
PODD Insulet Corporation	138.92 mm	600.00 k shares	3.07	Common equity	Long	USA
SYK Stryker Corporation	119.35 mm	335.00 k shares	2.64	Common equity	Long	USA
MASI Masimo Corporation	115.21 mm	800.00 k shares	2.54	Common equity	Long	USA
REGN Regeneron Pharmaceuticals, Inc.	112.32 mm	134.00 k shares	2.48	Common equity	Long	USA
TMO Thermo Fisher Scientific Inc.	109.26 mm	200.00 k shares	2.41	Common equity	Long	USA
ARGX argenx SE	102.02 mm	174.00 k shares	2.25	Common equity	Long	Netherlands
MCK McKesson Corporation	100.12 mm	200.00 k shares	2.21	Common equity	Long	USA
ALNY Alnylam Pharmaceuticals, Inc.	98.64 mm	370.00 k shares	2.18	Common equity	Long	USA
Cigna Holding Co	96.96 mm	308.00 k shares	2.14	Common equity	Long	USA
EXAS Exact Sciences Corporation	90.99 mm	1.32 mm shares	2.01	Common equity	Long	USA
MRK Merck & Co., Inc.	79.81 mm	780.00 k shares	1.76	Common equity	Long	USA
PCVX Vaxcyte, Inc.	74.44 mm	700.00 k shares	1.64	Common equity	Long	USA
UCB SA	74.04 mm	385.00 k shares	1.63	Common equity	Long	Belgium
LEGN Legend Biotech Corporation	72.03 mm	1.60 mm shares	1.59	Common equity	Long	Cayman Islands
VEEV Veeva Systems Inc.	69.96 mm	335.00 k shares	1.54	Common equity	Long	USA
GKOS Glaukos Corporation	69.83 mm	528.00 k shares	1.54	Common equity	Long	USA
SGRY Surgery Partners, Inc.	66.82 mm	2.32 mm shares	1.48	Common equity	Long	USA
ASND Ascendis Pharma A/S	63.25 mm	515.00 k shares	1.40	Common equity	Long	Denmark
Fidelity Cash Central Fund	59.25 mm	59.24 mm shares	1.31	Short-term investment vehicle	Long	USA
ISRG Intuitive Surgical, Inc.	54.41 mm	108.00 k shares	1.20	Common equity	Long	USA
ELV Elevance Health Inc.	51.94 mm	128.00 k shares	1.15	Common equity	Long	USA
PRVA Privia Health Group, Inc.	45.90 mm	2.50 mm shares	1.01	Common equity	Long	USA
INSP Inspire Medical Systems, Inc.	44.47 mm	228.00 k shares	0.98	Common equity	Long	USA
ASTRAZENECA PLC	43.83 mm	308.00 k shares	0.97	Common equity	Long	UK
MOH Molina Healthcare, Inc.	41.76 mm	130.00 k shares	0.92	Common equity	Long	USA
BRKR Bruker Corporation	41.33 mm	730.00 k shares	0.91	Common equity	Long	USA
ALHC Alignment Healthcare, Inc.	38.94 mm	3.14 mm shares	0.86	Common equity	Long	USA
NUVL Nuvalent, Inc.	37.63 mm	425.30 k shares	0.83	Common equity	Long	USA
PRCT PROCEPT BioRobotics Corporation	36.00 mm	400.00 k shares	0.79	Common equity	Long	USA
CYTK Cytokinetics, Incorporated	35.70 mm	700.00 k shares	0.79	Common equity	Long	USA
BNTX BioNTech SE	33.93 mm	300.00 k shares	0.75	Common equity	Long	Germany
MERUS B.V.	33.00 mm	660.87 k shares	0.73	Common equity	Long	Netherlands
XENE Xenon Pharmaceuticals Inc.	32.07 mm	780.00 k shares	0.71	Common equity	Long	Canada
ROYALTY PHARMA PLC	31.86 mm	1.18 mm shares	0.70	Common equity	Long	UK
LFST LifeStance Health Group, Inc.	28.72 mm	4.28 mm shares	0.63	Common equity	Long	USA
BTSG BrightSpring Health Services, Inc. Common Stock	27.69 mm	1.85 mm shares	0.61	Common equity	Long	USA
TXG 10x Genomics, Inc.	26.81 mm	1.67 mm shares	0.59	Common equity	Long	USA
GILD Gilead Sciences, Inc.	26.65 mm	300.00 k shares	0.59	Common equity	Long	USA
VRDN Viridian Therapeutics, Inc.	25.88 mm	1.20 mm shares	0.57	Common equity	Long	USA
ACLX Arcellx, Inc.	23.60 mm	280.00 k shares	0.52	Common equity	Long	USA
KROS Keros Therapeutics, Inc.	23.22 mm	400.00 k shares	0.51	Common equity	Long	USA
JANX Janux Therapeutics, Inc.	23.19 mm	429.50 k shares	0.51	Common equity	Long	USA
WST West Pharmaceutical Services, Inc.	20.02 mm	65.00 k shares	0.44	Common equity	Long	USA
MLTX MoonLake Immunotherapeutics	19.73 mm	425.00 k shares	0.44	Common equity	Long	Cayman Islands
GPCR Structure Therapeutics Inc.	16.95 mm	412.00 k shares	0.37	Common equity	Long	Cayman Islands
CRNX Crinetics Pharmaceuticals, Inc.	16.79 mm	300.00 k shares	0.37	Common equity	Long	USA
BPMC Blueprint Medicines Corporation	16.63 mm	190.00 k shares	0.37	Common equity	Long	USA
PHR Phreesia, Inc.	16.53 mm	903.74 k shares	0.36	Common equity	Long	USA
ORKA Oruka Therapeutics Inc.	15.73 mm	561.71 k shares	0.35	Common equity	Long	USA
NRIX Nurix Therapeutics, Inc.	14.69 mm	597.81 k shares	0.32	Common equity	Long	USA
UPB Upstream Bio, Inc.	12.95 mm	521.98 k shares	0.29	Common equity	Long	USA
RVMD Revolution Medicines, Inc.	12.84 mm	240.00 k shares	0.28	Common equity	Long	USA
RNA Avidity Biosciences, Inc.	12.68 mm	300.00 k shares	0.28	Common equity	Long	USA
CRGX CARGO Therapeutics, Inc. Common Stock	12.43 mm	637.20 k shares	0.27	Common equity	Long	USA
PHARVARIS BV	12.00 mm	482.49 k shares	0.26	Common equity	Long	Netherlands
DYN Dyne Therapeutics, Inc.	11.54 mm	400.00 k shares	0.25	Common equity	Long	USA
SLNO Soleno Therapeutics, Inc.	11.01 mm	200.00 k shares	0.24	Common equity	Long	USA
SYRE Spyre Therapeutics, Inc.	10.73 mm	330.00 k shares	0.24	Common equity	Long	USA
COGT Cogent Biosciences, Inc.	10.34 mm	900.00 k shares	0.23	Common equity	Long	USA
ICUI ICU Medical, Inc.	10.24 mm	60.00 k shares	0.23	Common equity	Long	USA
ELVN Enliven Therapeutics, Inc.	10.03 mm	360.00 k shares	0.22	Common equity	Long	USA
CLEERLY INC SER C PC PP	9.54 mm	882.09 k shares	0.21	Preferred equity	Long	USA
DAWN Day One Biopharmaceuticals, Inc.	8.83 mm	600.00 k shares	0.20	Common equity	Long	USA
CLDX Celldex Therapeutics, Inc.	8.34 mm	320.00 k shares	0.18	Common equity	Long	USA
IMCR Immunocore Holdings plc	8.05 mm	261.15 k shares	0.18	Common equity	Long	UK
ALLO Allogene Therapeutics, Inc.	7.67 mm	3.00 mm shares	0.17	Common equity	Long	USA
KARDIUM INC CONV 10% 12/31/2026 PP	7.59 mm	7.82 mm principal	0.17	Preferred equity	Long	Canada
RCUS Arcus Biosciences, Inc.	6.89 mm	450.00 k shares	0.15	Common equity	Long	USA
CARIS LIFE SCIENCES INC SER D PC PP	6.62 mm	2.08 mm shares	0.15	Preferred equity	Long	USA
MEDICAL MICROINSTRUMENTS INC SER C PC PP	6.61 mm	199.63 k shares	0.15	Preferred equity	Long	USA
SMMT Summit Therapeutics Inc.	6.51 mm	350.00 k shares	0.14	Common equity	Long	USA
INSIGHTEC LTD SER G PC PP	6.36 mm	7.39 mm shares	0.14	Preferred equity	Long	Israel
ENDEAVOR BIOMEDICINES INC SERIES C PC PP	6.20 mm	863.75 k shares	0.14	Preferred equity	Long	USA
OMADA HEALTH INC SER E PC PP	5.92 mm	1.46 mm shares	0.13	Preferred equity	Long	USA
IQV IQVIA Holdings Inc.	5.76 mm	28.00 k shares	0.13	Common equity	Long	USA
SALUDA MEDICAL INC SER E PC PP	5.50 mm	781.58 k shares	0.12	Preferred equity	Long	USA
AGL agilon health, inc.	5.10 mm	2.00 mm shares	0.11	Common equity	Long	USA
ALEDADE INC SER B1 PC PP	4.95 mm	130.62 k shares	0.11	Preferred equity	Long	USA
RNAC Cartesian Therapeutics, Inc.	4.56 mm	230.25 k shares	0.10	Common equity	Long	USA
CATX Perspective Therapeutics, Inc.	4.13 mm	350.00 k shares	0.09	Common equity	Long	USA
ELEMENT BIOSCIENCES INC SER C PC PP	4.03 mm	376.69 k shares	0.09	Preferred equity	Long	USA
RAPP Rapport Therapeutics, Inc. Common Stock	3.92 mm	160.00 k shares	0.09	Common equity	Long	USA
CARIS LIFE SCIENCES INC PP	3.49 mm	1.10 mm shares	0.08	Common equity	Long	USA
PSTX Poseida Therapeutics, Inc.	3.45 mm	1.45 mm shares	0.08	Common equity	Long	USA
VKTX Viking Therapeutics, Inc.	3.15 mm	43.40 k shares	0.07	Common equity	Long	USA
NMRA Neumora Therapeutics, Inc. Common Stock	3.08 mm	269.21 k shares	0.07	Common equity	Long	USA
SEPN Septerna, Inc. Common Stock	2.98 mm	130.20 k shares	0.07	Common equity	Long	USA
ASIMOV INC SER B PC PP	2.75 mm	67.55 k shares	0.06	Preferred equity	Long	USA
INSCRIPTA INC SER E PC PP	2.49 mm	826.42 k shares	0.05	Preferred equity	Long	USA
CANDID THERAPEUTICS INC SER B PC PP	2.35 mm	1.96 mm shares	0.05	Preferred equity	Long	USA
GALVANIZE THERAPEUTICS CONV 6% 02/28/2027 P/P	2.25 mm	2.08 mm principal	0.05	Debt	Long	USA
GALVANIZE THERAPEUTICS SER B PC PERP PP	2.17 mm	2.55 mm shares	0.05	Preferred equity	Long	USA
THRD Third Harmonic Bio, Inc.	2.16 mm	156.70 k shares	0.05	Common equity	Long	USA
CTNM Contineum Therapeutics, Inc. Class A Common Stock	2.15 mm	128.00 k shares	0.05	Common equity	Long	USA
ABOS Acumen Pharmaceuticals, Inc.	2.02 mm	700.00 k shares	0.04	Common equity	Long	USA
ELEMENT BIOSCIENCES INC SER D1 PC PP	1.93 mm	246.62 k shares	0.04	Preferred equity	Long	USA
ELEMENT BIOSCIENCES INC SER D PC PP	1.93 mm	246.62 k shares	0.04	Preferred equity	Long	USA
ALEDADE INC SER E1 PC PP	1.76 mm	46.53 k shares	0.04	Preferred equity	Long	USA
APGE Apogee Therapeutics, Inc.	1.73 mm	33.30 k shares	0.04	Common equity	Long	USA
FAHEAL THRIVE HOLDINGS LLC	1.69 mm	327.59 k shares	0.04	Common equity	Long	USA
JADE BIOSCIENCES INC PIPE	1.59 mm	320.77 k shares	0.04	Common equity	Long	USA
WUGEN INC CONV 10% 06/14/2025 PP	1.50 mm	1.43 mm principal	0.03	Debt	Long	USA
ORUKA THERAPEUTICS INC PIPE	1.37 mm	48.98 k shares	0.03	Common equity	Long	USA
DMED BIOPHARMACEUTICAL CO LTD SER C PC PP	1.28 mm	236.14 k shares	0.03	Preferred equity	Long	China
SRRK Scholar Rock Holding Corporation	1.27 mm	44.74 k shares	0.03	Common equity	Long	USA
WUGEN INC SER B PC PP	1.26 mm	300.05 k shares	0.03	Preferred equity	Long	USA
ZEALAND PHARMA A/S	1.05 mm	9.10 k shares	0.02	Common equity	Long	Denmark
ORUKA THERAPEUTICS INC SER A PC PP	532.00 k	19.00 shares	0.01	Preferred equity	Long	USA
ELEVATEBIO LLC SER C PC PP	509.50 k	163.30 k shares	0.01	Preferred equity	Long	USA
MEDICAL MICROINSTRUMENTS INC WT 02/16/2031 PP	121.88 k	9.98 k shares	0.00	Common equity	Long	USA
ANNX Annexon, Inc.	102.79 k	14.04 k shares	0.00	Common equity	Long	USA