Health Sciences Portfolio

Fund Profile

Fund profile

Fund manager

Pacific Select Fund

Total assets

$419.01 mm

Liabilities

$449.02 k

Net assets

$418.56 mm

Number of holdings

120.00

120 Holdings

As of Sep 2024

Security	$Holding	Balance	% of Fund	Category	Position	Country
UNH UnitedHealth Group Incorporated	39.65 mm	67.82 k shares	9.47	Common equity	Long	USA
LLY Eli Lilly and Company	38.63 mm	43.61 k shares	9.23	Common equity	Long	USA
BSX Boston Scientific Corporation	25.30 mm	301.93 k shares	6.04	Common equity	Long	USA
AMGN Amgen Inc.	16.42 mm	50.95 k shares	3.92	Common equity	Long	USA
DHR Danaher Corporation	14.93 mm	53.70 k shares	3.57	Common equity	Long	USA
ISRG Intuitive Surgical, Inc.	14.73 mm	29.99 k shares	3.52	Common equity	Long	USA
ABBV AbbVie Inc.	14.56 mm	73.73 k shares	3.48	Common equity	Long	USA
TMO Thermo Fisher Scientific Inc.	12.82 mm	20.72 k shares	3.06	Common equity	Long	USA
SYK Stryker Corporation	12.15 mm	33.64 k shares	2.90	Common equity	Long	USA
ELV Elevance Health Inc.	12.04 mm	23.16 k shares	2.88	Common equity	Long	USA
MRK Merck & Co., Inc.	11.19 mm	98.57 k shares	2.67	Common equity	Long	USA
COR Cencora	9.48 mm	42.10 k shares	2.26	Common equity	Long	USA
ABT Abbott Laboratories	9.30 mm	81.57 k shares	2.22	Common equity	Long	USA
JNJ Johnson & Johnson	9.18 mm	56.65 k shares	2.19	Common equity	Long	USA
GILD Gilead Sciences, Inc.	8.61 mm	102.67 k shares	2.06	Common equity	Long	USA
VRTX Vertex Pharmaceuticals Incorporated	8.49 mm	18.25 k shares	2.03	Common equity	Long	USA
REGN Regeneron Pharmaceuticals, Inc.	7.57 mm	7.21 k shares	1.81	Common equity	Long	USA
Cigna Holding Co	7.43 mm	21.45 k shares	1.78	Common equity	Long	USA
ALNY Alnylam Pharmaceuticals, Inc.	6.67 mm	24.27 k shares	1.59	Common equity	Long	USA
PFE Pfizer Inc.	6.29 mm	217.35 k shares	1.50	Common equity	Long	USA
MCK McKesson Corporation	6.14 mm	12.42 k shares	1.47	Common equity	Long	USA
ARGX argenx SE	5.95 mm	10.97 k shares	1.42	Common equity	Long	Netherlands
BIIB Biogen Inc.	5.53 mm	28.53 k shares	1.32	Common equity	Long	USA
BDX Becton, Dickinson and Company	5.49 mm	22.76 k shares	1.31	Common equity	Long	USA
EW Edwards Lifesciences Corporation	5.41 mm	81.91 k shares	1.29	Common equity	Long	USA
ZTS Zoetis Inc.	5.35 mm	27.41 k shares	1.28	Common equity	Long	USA
HCA HCA Healthcare, Inc.	5.25 mm	12.91 k shares	1.25	Common equity	Long	USA
FIXED INC CLEARING CORP.REPO Fixed Income Clearing Corp.	4.47 mm	4.47 mm principal	1.07	Repurchase agreement	Long	USA
Medtronic PLC	4.46 mm	49.49 k shares	1.06	Common equity	Long	Ireland
GEHC GE HealthCare Technologies Inc.	4.24 mm	45.23 k shares	1.01	Common equity	Long	USA
COO The Cooper Companies, Inc.	3.53 mm	32.02 k shares	0.84	Common equity	Long	USA
Sanofi SA	3.42 mm	29.70 k shares	0.82	Common equity	Long	France
HUM Humana Inc.	3.17 mm	10.01 k shares	0.76	Common equity	Long	USA
CNC Centene Corporation	2.94 mm	39.08 k shares	0.70	Common equity	Long	USA
SRPT Sarepta Therapeutics, Inc.	2.92 mm	23.36 k shares	0.70	Common equity	Long	USA
AstraZeneca PLC	2.69 mm	17.25 k shares	0.64	Common equity	Long	UK
NTRA Natera, Inc.	2.37 mm	18.64 k shares	0.57	Common equity	Long	USA
IDXX IDEXX Laboratories, Inc.	2.27 mm	4.49 k shares	0.54	Common equity	Long	USA
INSM Insmed Incorporated	2.24 mm	30.68 k shares	0.53	Common equity	Long	USA
WST West Pharmaceutical Services, Inc.	2.10 mm	6.99 k shares	0.50	Common equity	Long	USA
Roche Holding AG	2.09 mm	6.54 k shares	0.50	Common equity	Long	Switzerland
Novo Nordisk A/S	1.94 mm	16.38 k shares	0.46	Common equity	Long	Denmark
NUVL Nuvalent, Inc.	1.94 mm	18.93 k shares	0.46	Common equity	Long	USA
PCVX Vaxcyte, Inc.	1.83 mm	15.98 k shares	0.44	Common equity	Long	USA
RYTM Rhythm Pharmaceuticals, Inc.	1.75 mm	33.40 k shares	0.42	Common equity	Long	USA
BPMC Blueprint Medicines Corporation	1.66 mm	17.98 k shares	0.40	Common equity	Long	USA
ACLX Arcellx, Inc.	1.60 mm	19.21 k shares	0.38	Common equity	Long	USA
STERIS PLC	1.60 mm	6.58 k shares	0.38	Common equity	Long	Ireland
PEN Penumbra, Inc.	1.57 mm	8.09 k shares	0.38	Common equity	Long	USA
WAT Waters Corporation	1.54 mm	4.28 k shares	0.37	Common equity	Long	USA
A Agilent Technologies, Inc.	1.54 mm	10.36 k shares	0.37	Common equity	Long	USA
ALGN Align Technology, Inc.	1.41 mm	5.54 k shares	0.34	Common equity	Long	USA
RGEN Repligen Corporation	1.39 mm	9.37 k shares	0.33	Common equity	Long	USA
DXCM DexCom, Inc.	1.27 mm	19.02 k shares	0.30	Common equity	Long	USA
DGX Quest Diagnostics Incorporated	1.20 mm	7.75 k shares	0.29	Common equity	Long	USA
MTD Mettler-Toledo International Inc.	1.20 mm	800.00 shares	0.29	Common equity	Long	USA
IQV IQVIA Holdings Inc.	1.08 mm	4.57 k shares	0.26	Common equity	Long	USA
EXAS Exact Sciences Corporation	1.08 mm	15.84 k shares	0.26	Common equity	Long	USA
ONC BeiGene, Ltd.	1.03 mm	4.59 k shares	0.25	Common equity	Long	Cayman Islands
LH Laboratory Corporation of America Holdings	1.02 mm	4.57 k shares	0.24	Common equity	Long	USA
BMRN BioMarin Pharmaceutical Inc.	1.02 mm	14.46 k shares	0.24	Common equity	Long	USA
XENE Xenon Pharmaceuticals Inc.	954.76 k	24.25 k shares	0.23	Common equity	Long	Canada
TECH Bio-Techne Corporation	900.49 k	11.27 k shares	0.22	Common equity	Long	USA
Zealand Pharma A/S	883.33 k	7.26 k shares	0.21	Common equity	Long	Denmark
INSP Inspire Medical Systems, Inc.	838.29 k	3.97 k shares	0.20	Common equity	Long	USA
Biohaven Ltd	829.50 k	16.60 k shares	0.20	Common equity	Long	Virgin Islands (British)
PTGX Protagonist Therapeutics, Inc.	795.11 k	17.67 k shares	0.19	Common equity	Long	USA
Daiichi Sankyo Co Ltd	789.47 k	23.90 k shares	0.19	Common equity	Long	Japan
Merus NV	776.48 k	15.54 k shares	0.19	Common equity	Long	Netherlands
NBIX Neurocrine Biosciences, Inc.	771.74 k	6.70 k shares	0.18	Common equity	Long	USA
DNLI Denali Therapeutics Inc.	698.07 k	23.96 k shares	0.17	Common equity	Long	USA
INCY Incyte Corporation	693.12 k	10.49 k shares	0.17	Common equity	Long	USA
NRIX Nurix Therapeutics, Inc.	685.60 k	30.51 k shares	0.16	Common equity	Long	USA
BNTX BioNTech SE	614.63 k	5.18 k shares	0.15	Common equity	Long	Germany
DYN Dyne Therapeutics, Inc.	596.67 k	16.61 k shares	0.14	Common equity	Long	USA
STOK Stoke Therapeutics, Inc.	587.89 k	47.84 k shares	0.14	Common equity	Long	USA
RNA Avidity Biosciences, Inc.	554.10 k	12.06 k shares	0.13	Common equity	Long	USA
RARE Ultragenyx Pharmaceutical Inc.	538.28 k	9.69 k shares	0.13	Common equity	Long	USA
IONS Ionis Pharmaceuticals, Inc.	515.05 k	12.86 k shares	0.12	Common equity	Long	USA
PTCT PTC Therapeutics, Inc.	505.12 k	13.62 k shares	0.12	Common equity	Long	USA
ASND Ascendis Pharma A/S	482.57 k	3.23 k shares	0.12	Common equity	Long	Denmark
GKOS Glaukos Corporation	466.40 k	3.58 k shares	0.11	Common equity	Long	USA
RVMD Revolution Medicines, Inc.	455.31 k	10.04 k shares	0.11	Common equity	Long	USA
Roivant Sciences Ltd	452.95 k	39.25 k shares	0.11	Common equity	Long	Bermuda
Helix Acquisition Corp II	440.52 k	42.16 k shares	0.11	Common equity	Long	Cayman Islands
LEGN Legend Biotech Corporation	433.36 k	8.89 k shares	0.10	Common equity	Long	Cayman Islands
GPCR Structure Therapeutics Inc.	423.28 k	9.64 k shares	0.10	Common equity	Long	Cayman Islands
SLNO Soleno Therapeutics, Inc.	420.08 k	8.32 k shares	0.10	Common equity	Long	USA
VKTX Viking Therapeutics, Inc.	390.69 k	6.17 k shares	0.09	Common equity	Long	USA
GH Guardant Health, Inc.	381.86 k	16.65 k shares	0.09	Common equity	Long	USA
MLTX MoonLake Immunotherapeutics	349.21 k	6.93 k shares	0.08	Common equity	Long	Cayman Islands
BEAM Beam Therapeutics Inc.	344.27 k	14.05 k shares	0.08	Common equity	Long	USA
Novocure Ltd	314.68 k	20.13 k shares	0.08	Common equity	Long	Jersey
BBIO BridgeBio Pharma, Inc.	291.52 k	11.45 k shares	0.07	Common equity	Long	USA
IMCR Immunocore Holdings plc	267.28 k	8.59 k shares	0.06	Common equity	Long	UK
CGON CG Oncology, Inc. Common stock	247.85 k	6.57 k shares	0.06	Common equity	Long	USA
IRON Disc Medicine, Inc.	245.95 k	5.01 k shares	0.06	Common equity	Long	USA
RCKT Rocket Pharmaceuticals, Inc.	232.76 k	12.60 k shares	0.06	Common equity	Long	USA
LBPH Longboard Pharmaceuticals, Inc.	227.84 k	6.84 k shares	0.05	Common equity	Long	USA
ALLO Allogene Therapeutics, Inc.	204.27 k	72.96 k shares	0.05	Common equity	Long	USA
AC Immune SA	200.91 k	53.15 k shares	0.05	Common equity	Long	Switzerland
NARI Inari Medical, Inc.	197.33 k	4.79 k shares	0.05	Common equity	Long	USA
Nyxoah SA	193.34 k	20.25 k shares	0.05	Common equity	Long	Belgium
Immatics NV	168.86 k	14.80 k shares	0.04	Common equity	Long	Netherlands
TCRX TScan Therapeutics, Inc.	167.30 k	33.60 k shares	0.04	Common equity	Long	USA
AUTL Autolus Therapeutics plc	159.71 k	44.00 k shares	0.04	Common equity	Long	UK
RGNX REGENXBIO Inc.	134.11 k	12.79 k shares	0.03	Common equity	Long	USA
VYGR Voyager Therapeutics, Inc.	129.34 k	22.11 k shares	0.03	Common equity	Long	USA
CABA Cabaletta Bio, Inc.	94.45 k	20.01 k shares	0.02	Common equity	Long	USA
FDMT 4D Molecular Therapeutics, Inc.	85.90 k	7.95 k shares	0.02	Common equity	Long	USA
SAGE Sage Therapeutics, Inc.	67.69 k	9.38 k shares	0.02	Common equity	Long	USA
PRME Prime Medicine, Inc.	63.86 k	16.50 k shares	0.02	Common equity	Long	USA
OBIO Orchestra BioMed Holdings, Inc.	63.83 k	12.42 k shares	0.02	Common equity	Long	USA
SGMT Sagimet Biosciences Inc.	41.55 k	15.00 k shares	0.01	Common equity	Long	USA
KYTX Kyverna Therapeutics, Inc.	32.23 k	6.59 k shares	0.01	Common equity	Long	USA
CONTRA ABIOMED INC	17.95 k	11.08 k shares	0.00	Equity derivative	N/A	USA
CONTRA MIRATI THERAPEU	8.11 k	10.82 k shares	0.00	Equity derivative	N/A	USA
NUVB Nuvation Bio Inc.	339.91	3.47 k shares	0.00	Equity derivative	N/A	USA
CMAXQ CareMax, Inc.	36.10	3.65 k shares	0.00	Equity derivative	N/A	USA
CONTRA FREQUENCY THERA	0.02	19.74 k shares	0.00	Equity derivative	N/A	USA