100 patents
Page 2 of 5
Utility
Detecting Melanoma
18 May 23
Provided herein is technology for primary cutaneous melanoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of primary cutaneous melanoma.
David A. Ahlquist, John B. Kisiel, William R. Taylor, Douglas W. Mahoney, Calise K. Berger, Hatim T. Allawi, Viatcheslav Katerov
Filed: 4 May 21
Utility
Fecal sample processing and analysis comprising detection of blood
25 Apr 23
A method of processing a fecal sample from a human subject comprising removing a portion of a collected fecal sample and adding the removed portion of the sample to a buffer that prevents denaturation or degradation of blood proteins found in the sample, and detecting the presence of human blood in the removed portion of the fecal sample.
Joost Louwagie
Filed: 28 Sep 22
Utility
Detection of Lung Neoplasia by Amplification of Rna Sequences
20 Apr 23
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
Hatim Allawi, Graham P. Lidgard, Chateen Krueger, Michael W. Kaiser, Tamara J. Sander
Filed: 15 Sep 22
Utility
Fecal Sample Processing and Analysis Comprising Detection of Blood
16 Feb 23
A method of processing a fecal sample from a human subject comprising removing a portion of a collected fecal sample and adding the removed portion of the sample to a buffer that prevents denaturation or degradation of blood proteins found in the sample, and detecting the presence of human blood in the removed portion of the fecal sample.
Joost Louwagie
Filed: 28 Sep 22
Utility
Structure and Temperature-dependent Flap Endonuclease Substrates
16 Feb 23
5′ hairpin oligonucleotide substrates for reversible repression, e.g., by temperature shift, of cleavage by flap endonucleases, and methods using 5′ hairpin oligonucleotides.
Zubin Gagrat, Michael B. Matter, Nicholas J. Domanico, Michael J. Domanico
Filed: 16 Sep 20
Utility
Characterizing Methylated Dna, Rna, and Proteins In Subjects Suspected of Having Lung Neoplasia
22 Dec 22
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.
Scott Morris, David Mallery, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos, Michael W. Kaiser, David A. Ahlquist, William R. Taylor, Douglas W. Mahoney
Filed: 27 Aug 20
Utility
Method for Stabilizing Hemoglobin and Reagents for Performing the Same
24 Nov 22
A stool resuspension solution comprising a hemoglobin stabilization reagent is provided.
Keith D. Fourrier, Jacquelyn T. Hennek, Michael J. Domanico, William G. Weisburg, Graham P. Lidgard, Kathleen S. Harings, Daniel J. Simpson
Filed: 6 Jun 22
Utility
Detecting Esophageal Disorders
3 Nov 22
Provided herein is technology for screening for esophageal disorders, including but not limited to, Barrett's esophagus (BE).
William R. Taylor, Tracy C. Yab, Douglas W. Mahoney, John B. Kisiel, David A. Ahlquist, Hatim T. Allawi, Graham P. Lidgard, Maria Giakoumopoulos
Filed: 22 Apr 22
Utility
Methylated Control Dna
27 Oct 22
Provided herein is technology relating compositions and methods for analysis of methylated DNA from a subject.
Hatim T. Allawi, Graham P. Lidgard
Filed: 10 May 22
Utility
Detection of lung neoplasia by amplification of RNA sequences
25 Oct 22
Provided herein is technology for lung neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of lung cancer.
Hatim Allawi, Graham P. Lidgard, Chateen Krueger, Michael W. Kaiser, Tamara J. Sander
Filed: 23 Oct 20
Utility
Multiplex Amplification Detection Assay
25 Aug 22
Provided herein is technology relating to the amplification-based detection of bisulfite-treated DNAs and particularly, but not exclusively, to methods and compositions for multiplex amplification of low-level sample DNA prior to further characterization of the sample DNA.
Graham P. Lidgard, Hatim Allawi
Filed: 11 Mar 22
Utility
Detecting the Presence or Absence of Multiple Types of Cancer
4 Aug 22
Provided herein is technology for screening multiple types of cancer from a biological sample, and particularly, but not exclusively, to methods, compositions, and related uses for simultaneously detecting the presence of multiple types of cancer (e.g., liver cancer, esophageal cancer, lung cancer, ovarian cancer, pancreatic cancer, gastric cancer, bladder cancer, breast cancer, cervical cancer, colorectal cancer, prostate cancer, renal cancer, and uterine cancer) from a biological sample (e.g., stool sample, tissue sample, organ secretion sample, CSF sample, saliva sample, blood sample, plasma sample or urine sample).
William R. Taylor, Hatim T. Allawi, Viatcheslav E. Katerov, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist
Filed: 28 Jan 22
Utility
Method for stabilizing hemoglobin and reagents for performing the same
12 Jul 22
A stool resuspension solution comprising a hemoglobin stabilization reagent is provided.
Keith D. Fourrier, Jacquelyn T. Hennek, Michael J. Domanico, William G. Weisburg, Graham P. Lidgard, Kathleen S. Harings, Daniel J. Simpson
Filed: 15 Mar 19
Utility
Detecting colorectal neoplasm
21 Jun 22
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.
David A. Ahlquist, William R. Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi
Filed: 30 Apr 19
Utility
Methylated control DNA
31 May 22
Provided herein is technology relating compositions and methods for analysis of methylated DNA from a subject.
Hatim T. Allawi, Graham P. Lidgard
Filed: 19 Jul 17
Utility
Detecting Pancreatic Ductal Adenocarcinoma In Plasma
26 May 22
Provided herein is technology for pancreatic ductal adenocarcinoma (PDAC) screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of PDAC.
William R. Taylor, John B. Kisiel, Douglas W. Mahoney, David A. Ahlquist, Hatim T. Allawi
Filed: 3 Apr 20
Utility
Nucleic Acid Control Molecules from Non-human Organisms
5 May 22
The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods.
Hatim T. Allawi, Graham P. Lidgard, Brian Aizenstein, Melissa M. Gray
Filed: 18 Nov 21
Utility
Compositions and Methods for Performing Methylation Detection Assays
10 Feb 22
Provided herein is technology relating to performing methylation assays.
David Alan Ahlquist, William Russell Taylor, Douglas W. Mahoney, Graham P. Lidgard, Hatim T. Allawi, Abram Michael Vaccaro
Filed: 23 Aug 21
Utility
Mutation Detection Assay
30 Dec 21
A method of sample analysis is provided.
Hongzhi Zou, Graham P. Lidgard, Michael J. Domanico, Hatim Allawi
Filed: 8 Jul 21
Utility
Nucleic acid control molecules from non-human organisms
28 Dec 21
The present invention provides synthetic DNA strands that find use as process controls in DNA processing and nucleic acid testing methods.
Hatim T. Allawi, Graham P. Lidgard, Brian Aizenstein, Melissa M. Gray
Filed: 19 Jul 17